782 research outputs found

    The academic thinking based on the perspective of fashion design

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    With the contemporary socio-economic, political, and cultural diversity, Fashion Design leads us toward a broader field rapidly. Under the "people-oriented" principle, Fashion design which integrating the design concept of multi-angle, multi-paradigm and multi-aspect should be on the stand of severing people so as to meet people\u27s physiological and mental needs and to enrich people\u27s spiritual and material life for the purpose. It further opens up a new vision for Modern fashion frontier and will be bound to the clothing design practice

    Cluster’s Competitiveness of Photoelectron Industry of Optics Valley of Wuhan Based on the GEM Model

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    Wuhan East Lake High-tech Zone was called Optics Valley of Wuhan ratified by the Ministry of Science and Technology of China in 2001, which became a national photoelectron industry base now. As time goes by, Optics Valley of Wuhan photoelectron industry cluster become more and more powerful, and it has become a major form of regional economy in gaining competitive advantages. This paper establishes a GEM model of optics Valley photoelectron industry Cluster, and creates its competitiveness evaluation system. At the same time, not only do we measure the cluster’s competitiveness by distributing questionnaires, but also preliminary analyze and evaluate the measurement results

    Biochemical Issues in Estimation of Cytosolic Free NAD/NADH Ratio

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    Cytosolic free NAD/NADH ratio is fundamentally important in maintaining cellular redox homeostasis but current techniques cannot distinguish between protein-bound and free NAD/NADH. Williamson et al reported a method to estimate this ratio by cytosolic lactate/pyruvate (L/P) based on the principle of chemical equilibrium. Numerous studies used L/P ratio to estimate the cytosolic free NAD/NADH ratio by assuming that the conversion in cells was at near-equilibrium but not verifying how near it was. In addition, it seems accepted that cytosolic free NAD/NADH ratio was a dependent variable responding to the change of L/P ratio. In this study, we show (1) that the change of lactate/glucose (percentage of glucose that converts to lactate by cells) and L/P ratio could measure the status of conversion between pyruvate + NADH and lactate + NAD that tends to or gets away from equilibrium; (2) that cytosolic free NAD/NADH could be accurately estimated by L/P only when the conversion is at or very close to equilibrium otherwise a calculation error by one order of magnitude could be introduced; (3) that cytosolic free NAD/NADH is stable and L/P is highly labile, that the highly labile L/P is crucial to maintain the homeostasis of NAD/NADH; (4) that cytosolic free NAD/NADH is dependent on oxygen levels. Our study resolved the key issues regarding accurate estimation of cytosolic free NAD/NADH ratio and the relationship between NAD/NADH and L/P

    Concession Period Decision Models for Public Infrastructure Projects Based on Option Games

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    Concession period is an important decision-making variable for the investment and construction of public infrastructure projects. However, we currently have few scientific methods to exactly determine the concession period. This paper managed to seek out concession period decision models for public infrastructure with option game theory, studied the influence of minimum government income guarantee and government investment on concession period, and demonstrated those models in the formulas mentioned in the paper. The research results showed that the increase of minimum government income guarantee value would shorten the concession period, while the increase of income volatility, that is, the uncertainty, would lengthen the concession period. In terms of government investment, optimal concession period would lengthen to some extent with the increase of government investment ratio and the income and the decrease of its guarantee value. Yet, optimal concession period would shorten in case of extreme highness of the government investment ratio due to its high guarantee value. And the government would accordingly shorten the concession period in case of the unchanged government investment ratio with the increased income volatility and risks. Still, the paper put forward the argument that the government would apply various guarantee methods and implement flexible concession period in accordance with the specific circumstances of public infrastructure projects
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