979 research outputs found

    CO2 Reforming with CH4 via Plasma Catalysis System

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    Reforming of CO2 and CH4 into syngas (mixture of H2/CO) can be an economical way to reduce anthropogenic emission of CO2 and CH4 and to generate alternative fuel. Up to date, catalysis and nonthermal plasma are two feasible techniques for CO2/CH4 reforming. However, both techniques face some obstacles which limit their applications. For catalysis, high energy consumption and catalyst deactivation are the major disadvantages while nonthermal plasma has the drawbacks of low selectivity and unwanted byproduct formation. To overcome the above obstacles, combining catalyst and nonthermal plasma as a hybrid system can induce synergistic effects to enhance syngas production rate and stability of the operating system. For the purpose of enhancing CO2 utilization efficiency, understanding the interactions between catalyst and nonthermal plasma is essential

    Aggregation induced photodynamic therapy enhancement based on linear and nonlinear excited FRET of fluorescent organic nanoparticles

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    A binary molecule can self-assemble to form fluorescent organic nanoparticles (FONs) based on the Aggregation-Induced Emission Enhancement (AIEE) property and subsequently, presents an efficient fluorescence resonance energy transfer (FRET) to generate singlet oxygen under linear and nonlinear light sources. Biologically, this FON-photosensitizer is much more phototoxic to cancer cells than to normal cells without significant dark toxicity. Eventually, a new approach, called FON FRET-PDT or AIEE FRET-PDT, to promote the PDT effect is expected

    Leveling Maintenance Mechanism by Using the Fabry-Perot Interferometer with Machine Learning Technology

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    This study proposes a method for maintaining parallelism of the optical cavity of a laser interferometer using machine learning. The Fabry-Perot interferometer is utilized as an experimental optical structure in this research due to its advantage of having a brief optical structure. The supervised machine learning method is used to train algorithms to accurately classify and predict the tilt angle of the plane mirror using labeled interference images. Based on the predicted results, stepper motors are fixed on a plane mirror that can automatically adjust the pitch and yaw angles. According to the experimental results, the average correction error and standard deviation in 17-grid classification experiment are 32.38 and 11.21 arcseconds, respectively. In 25-grid classification experiment, the average correction error and standard deviation are 19.44 and 7.86 arcseconds, respectively. The results show that this parallelism maintenance technology has essential for the semiconductor industry and precision positioning technology

    Polymorphisms of the XRCC1, XRCC3, & XPD genes, and colorectal cancer risk: a case-control study in Taiwan

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    BACKGROUND: Recent studies relating to the association between DNA repair-gene polymorphisms and colorectal cancer risk would, to the best of our knowledge, appear to be very limited. This study was designed to examine the polymorphisms associated with three DNA repair genes, namely: XRCC1 Arg399Gln, XRCC3 Thr241Met and XPD Lys751Gln, and investigate their role as susceptibility markers for colorectal cancer. METHODS: We conducted a case-control study including 727 cases of cancer and 736 hospital-based age- and sex-matched healthy controls to examine the role of genetic polymorphisms of three DNA-repair genes (XRCC1, XRCC3 and XPD) in the context of colorectal cancer risk for the Taiwanese population. Genomic DNA isolated from 10 ml whole blood was used to genotype XRCC1 Arg399Gln, XRCC3 Thr241Met and XPD Lys751Gln by means of polymerase chain reaction (PCR) and restriction fragment length polymorphism (RFLP) analysis. RESULTS: The risk for colorectal cancer did not appear to differ significantly amongst individuals featuring the XRCC1 399Arg/Arg genotype (OR = 1.18; 95% CI, 0.96–1.45), the XRCC3 241Thr/Thr genotype (OR = 1.25; 95% CI, 0.88–1.79) or the XPD 751Gln allele (OR = 1.20; 95% CI, 0.90–1.61), although individuals featuring a greater number of risk genotypes (genotype with OR greater than 1) did experience a higher risk for colorectal cancer when compared to those who didn't feature any risk genotypes (Trend test P = 0.03). Compared with those individuals who didn't express any putative risk genotypes, individuals featuring all of the putative risk genotypes did experience a significantly greater cancer risk (OR = 2.43, 95% CI = 1.21–4.90), particularly for individuals suffering tumors located in the rectum (OR = 3.18, 95% CI = 1.29–7.82) and diagnosed prior to the age of 60 years (OR = 4.90, 95% CI = 1.72–14.0). CONCLUSIONS: Our results suggest that DNA-repair pathways may simultaneously modulate the risk of colorectal cancer for the Taiwanese population, and, particularly for rectal cancer and younger patients

    Construction and Characterization of Insect Cell-Derived Influenza VLP: Cell Binding, Fusion, and EGFP Incorporation

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    We have constructed virus-like particles (VLPs) harboring hemagglutinin (HA), neuraminidase (NA), matrix protein 1 (M1) ,and proton channel protein (M2) using baculovirus as a vector in the SF9 insect cell. The size of the expressed VLP was estimated to be ~100 nm by light scattering experiment and transmission electron microscopy. Recognition of HA on the VLP surface by the HA2-specific monoclonal antibody IIF4 at acidic pH, as probed by surface plasmon resonance, indicated the pH-induced structural rearrangement of HA. Uptake of the particle by A549 mediated by HA-sialylose receptor interaction was visualized by the fluorescent-labeled VLP. The HA-promoted cell-virus fusion activity was illustrated by fluorescence imaging on the Jurkat cells incubated with rhodamine-loaded VLP performed at fusogenic pH. Furthermore, the green fluorescence protein (GFP) was fused to NA to produce VLP with a pH-sensitive probe, expanding the use of VLP as an antigen carrier and a tool for viral tracking
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