Comparative Study of Conversion of Coral with Ammonium Dihydrogen Phosphate and Orthophosphoric Acid to Produce Calcium Phosphates

address significant advantages due to their unique structures and chemical compositions that contain Mg and Sr. Many conversion processes has been in the past proposed. In this work, a comparison study between the conversion of coral with orthophosphoric acid and ammonium dihydrogen phosphate was conducted. The resultant structures and compositions were studied using XRD, ICP-MS, SEM and FTIR. The results show that with phosphoric acid the coral was converted into mainly monetite (92%). The ammonium dihydrogen phosphate converted approximately 76% of the coral to hydroxyapatite through solid state reactions. The two routes proved to be effective in producing bioceramic materials from corals under moderate conditions of temperature with a basic condition favouring the yield of hydroxyapatite

Assessing suitability of Co@Au core/shell nanoparticle geometry for improved theranostics in colon carcinoma

The interactions between cells and nanomaterials at the nanoscale play a pivotal role in controlling cellular behavior and ample evidence links cell intercommunication to nanomaterial size. However, little is known about the effect of nanomaterial geometry on cell behavior. To elucidate this and to extend the application in cancer theranostics, we have engineered core–shell cobalt–gold nanoparticles with spherical (Co@Au NPs) and elliptical morphology (Co@Au NEs). Our results show that owing to superparamagnetism, Co@Au NPs can generate hyperthermia upon magnetic field stimulation. In contrast, due to the geometric difference, Co@Au NEs can be optically excited to generate hyperthermia upon photostimulation and elevate the medium temperature to 45 °C. Both nanomaterial geometries can be employed as prospective contrast agents; however, at identical concentration, Co@Au NPs exhibited 4-fold higher cytotoxicity to L929 fibroblasts as compared to Co@Au NEs, confirming the effect of nanomaterial geometry on cell fate. Furthermore, photostimulation-generated hyperthermia prompted detachment of anti-cancer drug, Methotrexate (MTX), from Co@Au NEs-MTX complex and which triggered 90% decrease in SW620 colon carcinoma cell viability, confirming their application in cancer theranostics. The geometry-based perturbation of cell fate can have a profound impact on our understanding of interactions at nano-bio interface which can be exploited for engineering materials with optimized geometries for superior theranostic applications

Preparation and Sensor Application of Carbon Coated Zinc Oxide Nanorods Array

[[abstract]]In this study, zinc oxide (ZnO) nanorod arrays (NRAs) coated with carbon material were fabricated onto a silicon substrate through a hydrothermal method followed by chemical vapor deposition. A series of tests were carried out, including crystallinity analysis, microstructure observation and investigation of the luminescent and electrical properties. We further constructed a nanosensing device for UV light and carbon monoxide (CO) through fabrication of a Schottky contact. The sensing abilities of the zinc oxide NRA devices before and after carbon coating were compared. The sensing mechanism was also investigated. The results indicated that the carbon coating was amorphous, with high mechanical strength, specific light transmittance and high resistance to chemical corrosion. After coating with carbon, the zinc oxide nanorods retained their original structure. In the UV light sensing test, the carbon layer retarded the electron transport, but the carbon-coated NRA device showed a higher average current in response to UV light compared to the bare NRA device. In the CO sensing experiment, the carbon coating provided functional groups for CO adsorption and improved the sensitivity.[[notice]]補正完畢[[booktype]]紙

Non-Enzymatic Glucose Sensor Composed of Carbon-Coated Nano-Zinc Oxide

Nowadays glucose detection is of great importance in the fields of biological, environmental, and clinical analyzes. In this research, we report a zinc oxide (ZnO) nanorod powder surface-coated with carbon material for non-enzymatic glucose sensor applications through a hydrothermal process and chemical vapor deposition method. A series of tests, including crystallinity analysis, microstructure observation, and electrochemical property investigations were carried out. For the cyclic voltammetric (CV) glucose detection, the low detection limit of 1 mM with a linear range from 0.1 mM to 10 mM was attained. The sensitivity was 2.97 μA/cm2mM, which is the most optimized ever reported. With such good analytical performance from a simple process, it is believed that the nanocomposites composed of ZnO nanorod powder surface-coated with carbon material are promising for the development of cost-effective non-enzymatic electrochemical glucose biosensors with high sensitivity

An Enzymatic Glucose Sensor Composed of Carbon-Coated Nano Tin Sulfide

In this study, a biosensor, based on a glucose oxidase (GOx) immobilized, carbon-coated tin sulfide (SnS) assembled on a glass carbon electrode (GCE) was developed, and its direct electrochemistry was investigated. The carbon coated SnS (C-SnS) nanoparticle was prepared through a simple two-step process, using hydrothermal and chemical vapor deposition methods. The large reactive surface area and unique electrical potential of C-SnS could offer a favorable microenvironment for facilitating electron transfer between enzymes and the electrode surface. The structure and sensor ability of the proposed GOx/C-SnS electrode were characterized using scanning electron microscopy (SEM), X-ray diffraction (XRD), Raman spectroscopy, UV–vis spectroscopy, Fourier transform infrared spectroscopy (FTIR), and cyclic voltammetry study (CV)

Bone-cements based on tricalcium silicate

[[abstract]]In this research, bone-cements based on zinc modified tricalcium silicate (C3S, Ca3SiO5) are synthesized through solid-state reactions. Zinc oxide was added to replace part of CaO in order to stabilize the C3S phase. The 7.5 mole % ZnO added samples showed the least free CaO impurity; the ones added with 5 mole % ZnO revealed the best compressive strength that reaches 166 MPa (compared with those without ZnO 100 MPa). In vitro direct contact tests using primary cultured osteoblast persuaded of no observable cytotoxicity. These cements show remarkable self-setting properties and good strength hence are potential in bony and dental restorations.[[fileno]]2020336030001[[department]]材料科學工程學

Integrated Oxidized-Hyaluronic Acid/Collagen Hydrogel with β-TCP Using Proanthocyanidins as a Crosslinker for Drug Delivery

The susceptibility of guided bone regeneration (GBR) material to infection by pathogens at wound sites during bone healing has often been overlooked. The objective of this study was the synthesis and characterization of a potential material for antibacterial GBR application. In the current study, the mechanical strength and biocompatibility of a composite restoration material—made of oxidized hyaluronic acid (HA)/type I collagen hydrogel integrated with tricalcium phosphate (β-TCP) using a natural crosslinking agent, oligomeric proanthocyanidins (OPCs)—were evaluated. The suitability of the material as a carrier matrix for antibacterial applications was evaluated by following the drug-release profile of tetracycline loaded within the composite. Results indicated that this composite material had a high swelling ratio of 420% and mechanical strength of 25 kPa while remaining at more than 60% of the weight after 30 days of an in vitro degradation test with good biocompatibility in promoting the proliferation of MG-63 cells. Drug release studies further showed that 93% of the tetracycline was released after 5 days, which supports this GBR material’s capability to release antibacterial drugs while keeping other required GBR material design functions

An Enzymatic Glucose Sensor Composed of Carbon-Coated Nano Tin Sulfide

In this study, a biosensor, based on a glucose oxidase (GOx) immobilized, carbon-coated tin sulfide (SnS) assembled on a glass carbon electrode (GCE) was developed, and its direct electrochemistry was investigated. The carbon coated SnS (C-SnS) nanoparticle was prepared through a simple two-step process, using hydrothermal and chemical vapor deposition methods. The large reactive surface area and unique electrical potential of C-SnS could offer a favorable microenvironment for facilitating electron transfer between enzymes and the electrode surface. The structure and sensor ability of the proposed GOx/C-SnS electrode were characterized using scanning electron microscopy (SEM), X-ray diffraction (XRD), Raman spectroscopy, UV–vis spectroscopy, Fourier transform infrared spectroscopy (FTIR), and cyclic voltammetry study (CV)