The Effects of Language Difference on Operational Performance and Satisfaction with B2B E-Marketplace Interface

This study integrated the user interface and information content of the business-to-business (B2B) electronic marketplace (e-marketplace) with language to analyze whether language differences affect the definition of good interface design and the information content that should be provided via an e-marketplace. An experimental design was adopted for collecting data from tasks, and then the Questionnaire for User Interface Satisfaction (QUIS) was used to ascertain how satisfied subjects were with regard to using the B2B e-marketplace interfaces. Study results showed that the language, the e-marketplace interface the subject used, and a combination of the two predict a person’s operational performance and satisfaction with a B2B e-marketplace. This study’s results provide a better understanding of whether B2B e-marketplace service providers should develop interfaces based on specific languages

Poly[diaqua­bis(μ3-1H-benzimidazole-5,6-dicarboxyl­ato-κ4 N 3:O 5,O 5′:O 6)bis­(μ2-1H,3H-benzimidazolium-5,6-dicarboxyl­ato-κ3 O 5,O 5′:O 6)digadolinium(III)]

In the title complex, [Gd2(C9H4N2O4)2(C9H5N2O4)2(H2O)2]n, two of the benzimidazole-5,6-dicarboxyl­ate ligands are pro­ton­ated at the imidazole groups. Each GdIII ion is coordinated by six O atoms and one N atom from five ligands and one water mol­ecule, displaying a distorted bicapped trigonal-prismatic geometry. The GdIII ions are linked by the carboxyl­ate groups and imidazole N atoms, forming a layer parallel to (001). These layers are further connected by O—H⋯O and N—H⋯O hydrogen bonds into a three-dimensional supra­molecular network

Cordycepin Induced MA-10 Mouse Leydig Tumor Cell Apoptosis through Caspase-9 Pathway

In the present study, the apoptotic effect of cordycepin on MA-10 cells, a mouse Leydig tumor cell line, was investigated. Results demonstrated that the number of rounding-up cell increased by cordycepin (10 μM to 5 mM for 24 h), and cells with plasma membrane blebbing could be observed by 100 μM cordycepin. In viability test, MA-10 cell surviving rate significantly decreased as the dosage (10 μM to 5 mM) and duration (3–24 h) of cordycepin treatment increased (P < 0.05). Cordycepin at 100 μM and 1 mM for 24 h treatment induced significant DNA fragmentation (P < 0.05). In addition, the percentage of G1 and G2/M phase cell significantly declined by cordycepin (100 μM and 1 mM) for 24 h treatment, while the percentages of subG1 phase cell increased by 100 μM and/or 1 mM cordycepin in 6, 12 and 24 h treatments (P < 0.05), respectively, which highly suggested that cordycepin induced MA-10 cell apoptosis. In mechanism study with the treatments of caspases, c-Jun NH2 terminal kinase (JNK) or reactive oxygen species (ROS) inhibitors plus cordycepin for 24 h, only caspases inhibitor suppressed subG1 phase in MA-10 cells. Moreover, western blotting results showed that cordycepin induced caspase-9, -3 and -7 protein expressions, but not caspase-8, in time- and dose-dependent manners. In conclusion, cordycepin induced apoptosis in MA-10 mouse Leydig tumor cells through a caspase-9 and -3 and -7 dependent pathway

Hemi(4,4′-bipyridinium) hexa­fluorido­phosphate bis­(4-amino­benzoic acid) 4,4′-bipyridine monohydrate

In the title compound, 0.5C10H10N2 2+·PF6 −·C10H8N2·2C7H7NO2·H2O, the cation is located on a center of symmetry. The crystal structure is determined by a complex three-dimensional network of inter­molecular O—H⋯O, O—H⋯N, N—H⋯N and N—H⋯F hydrogen bonds. π–π stacking inter­actions between neighboring pyridyl rings are also present; the centroid–centroid distance is 3.643 (5) Å. The hexa­fluoridophosphate anion is disordered over two positions with site-occupancy factors of ca 0.6 and 0.4

Ursolic Acid Florotriazole Treatment Causes Inhibition of Squamous Cell Carcinoma through Fas Signaling Pathway

Purpose: To investigate the effect of ursolic acid florotriazole (UFT), on SCC-15 oral squamous cancer cells.Methods: Confocal laser microscope with a 490 nm argon laser was used to record the fluorescence of the cells and capture the images. Flow cytometry and Cell Quest program were used to analyze the DNA content of the stained cells. Apoptosis was characterized by YO-PRO-1 staining.Results: Treatment of SCC-15 cells with UFT for 48 h significantly reduced cell viability in a dosedependent manner. At 20 μg/mL concentration of UFT, SCC-15, cell viability was reduced to 19 % compared to 100 % in the untreated cells (p = 0.0002). UFT treatment enhanced the proportion of apoptotic cells which was evident from YO-PRO-1 staining. In UFT-treated cultures, the population of cells in sub-G1 phase increased to 38.54 % compared to 7.32 % for control after 48 h. Expression of Fas in UFT-treated cells was also higher (p = 0.0002) than in untreated cells. In C3H/HeJ mice, administration of UFT daily for 14 days caused a significant (p = 0.0002) reduction in tumor volume and weight after 30 days of SCC-15 carcinoma cell administration.Conclusion: UFT treatment inhibits viability and induces apoptosis in squamous cell carcinoma cells through suppression of Fas expression. Therefore, UFT may be useful for the treatment of squamous cell cancer.Keywords: Ursolic acid florotriazole, Squamous cell cancer, Fas expression, Tumor volume, Cell viability, Apoptosi

Traumatic asphyxia combined with diffuse axonal injury

AbstractTraumatic asphyxia, a rare, blunt chest trauma-related condition, indicates severe injury and is characterized by subconjunctival hemorrhage, facial edema, cyanosis, and petechiae. This condition mostly appears on the upper chest and face. Rapid oxygen administration with effective ventilation is essential in the treatment of traumatic asphyxia. Prognosis depends on rescue time and associated injuries. Most neurologic symptoms resolve within 24–48 hours and have relatively satisfactory results over a long-term follow-up. We herein report the case of severe and complicated thoracoabdominal compression with a delayed change in consciousness. Susceptibility-weighted magnetic resonance imaging revealed diffuse axonal injury with multifocal microhemorrhages in the brain stem, basal ganglia, internal capsules, and the genu and splenium of the corpus callosum. The patient was in the intensive care unit for more than 21 days