Content-Aware Quantization Index Modulation:Leveraging Data Statistics for Enhanced Image Watermarking

Image watermarking techniques have continuously evolved to address new challenges and incorporate advanced features. The advent of data-driven approaches has enabled the processing and analysis of large volumes of data, extracting valuable insights and patterns. In this paper, we propose two content-aware quantization index modulation (QIM) algorithms: Content-Aware QIM (CA-QIM) and Content-Aware Minimum Distortion QIM (CAMD-QIM). These algorithms aim to improve the embedding distortion of QIM-based watermarking schemes by considering the statistics of the cover signal vectors and messages. CA-QIM introduces a canonical labeling approach, where the closest coset to each cover vector is determined during the embedding process. An adjacency matrix is constructed to capture the relationships between the cover vectors and messages. CAMD-QIM extends the concept of minimum distortion (MD) principle to content-aware QIM. Instead of quantizing the carriers to lattice points, CAMD-QIM quantizes them to close points in the correct decoding region. Canonical labeling is also employed in CAMD-QIM to enhance its performance. Simulation results demonstrate the effectiveness of CA-QIM and CAMD-QIM in reducing embedding distortion compared to traditional QIM. The combination of canonical labeling and the minimum distortion principle proves to be powerful, minimizing the need for changes to most cover vectors/carriers. These content-aware QIM algorithms provide improved performance and robustness for watermarking applications.Comment: 12 pages, 10 figure

Elevated circulating level of P2X7 receptor is related to severity of coronary artery stenosis and prognosis of acute myocardial infarction

Background: Acute myocardial infarction (AMI) is a severely life-threatening cardiovascular disease. Previous research has identified an association between the P2X7 receptor (P2X7R) and the development of atherosclerosis. However, the correlation of its expression with the clinical prognosis of patients with AMI remains unclear. The present study aimed to investigate the potential role of P2X7R in Chinese patients with AMI. Methods: Seventy-nine patients with AMI and 48 controls were consecutively enrolled in this prospective observational study. Circulating P2X7R mRNA expression levels and other clinical variables were determined upon admission to the hospital. Patients were followed up for 360 days, and the end-point was considered as the occurrence of major adverse cardiovascular events (MACE). Results: Circulating P2X7R mRNA expression level in peripheral blood mononuclear cells of patients with AMI were significantly higher than those in controls and had promising diagnostic ability of AMI with an area under the curve of 0.928. Furthermore, P2X7R was demonstrated to be correlated positively with the severity of coronary artery stenosis. Additionally, this is the first study to indicate that higher P2X7R mRNA expression is associated with a higher rate of MACE within 360 days after AMI. Conclusions: The present study showed that the circulating level of P2X7R was elevated in AMI patients and was closely associated with the severity of coronary artery stenosis and prognosis of AMI

Promoting Molecular Exchange on Rare-Earth Oxycarbonate Surfaces to Catalyze the Water-Gas Shift Reaction

It is highly desirable to fabricate an accessible catalyst surface that can efficiently activate reactants and desorb products to promote the local surface reaction equilibrium in heterogeneous catalysis. Herein, rare-earth oxycarbonates (Ln2O2CO3, where Ln = La and Sm), which have molecular-exchangeable (H2O and CO2) surface structures according to the ordered layered arrangement of Ln2O22+ and CO32- ions, are unearthed. On this basis, a series of Ln2O2CO3-supported Cu catalysts are prepared through the deposition precipitation method, which provides excellent catalytic activity and stability for the water-gas shift (WGS) reaction. Density functional theory calculations combined with systematic experimental characterizations verify that H2O spontaneously dissociates on the surface of Ln2O2CO3 to form hydroxyl by eliminating the carbonate through the release of CO2. This interchange efficiently promotes the WGS reaction equilibrium shift on the local surface and prevents the carbonate accumulation from hindering the active sites. The discovery of the unique layered structure provides a so-called "self-cleaning" active surface for the WGS reaction and opens new perspectives about the application of rare-earth oxycarbonate nanomaterials in C1 chemistry

A random quantum key distribution by using Bell states

We proposed a new scheme for quantum key distribution based on entanglement swapping. By this protocol \QTR{em}{Alice} can securely share a random quantum key with \QTR{em}{Bob}, without transporting any particle.Comment: Accepted by J. Opt. B: Quantum Semiclass. Op

Effects of 24-week treatment with acarbose on glucagon-like peptide 1 in newly diagnosed type 2 diabetic patients: a preliminary report

BACKGROUND: Treatment with the alpha-glucosidase inhibitor (AGI) acarbose is associated with a significant reduction the risk of cardiovascular events. However, the underlying mechanisms of this effect are unclear. AGIs were recently suggested to participate in stimulating glucagon-like peptide 1 (GLP-1) secretion. We therefore examined the effects of a 24-week treatment of acarbose on endogenous GLP-1, nitric oxide (NO) levels, nitric oxide synthase (NOS) activity, and carotid intima-media thickness (CIMT) in newly diagnosed patients with type 2 diabetes (T2D). METHODS: Blood was drawn from 24 subjects (14 male, 10 female, age: 50.7 ± 7.36 years, BMI: 26.64 ± 3.38 kg/m(2), GHbA1c: 7.00 ± 0.74%) with drug-naïve T2D at 0 and 120 min following a standard mixed meal for the measurements of active GLP-1, NO and NOS. The CIMT was measured prior to and following 24 weeks of acarbose monotherapy (mean dose: 268 mg daily). RESULTS: Following 24 weeks of acarbose treatment, both fasting and postprandial plasma GLP-1 levels were increased. In patients with increased postprandial GLP-1 levels, serum NO levels and NOS activities were also significantly increased and were positively related to GLP-1 levels. Although the CIMT was not significantly altered following treatment with acarbose, a decreased CIMT was negatively correlated with increased GLP-1 levels. CONCLUSIONS: Twenty-four weeks of acarbose monotherapy in newly diagnosed patients with T2D is associated with significantly increased levels of both fasting and postprandial GLP-1 as well as significantly increased NO levels and NOS activity for those patients in whom postprandial GLP-1 levels were increased. Therefore, the benefits of acarbose on cardiovascular risk may be related to its stimulation of GLP-1 secretion

Hydroxysafflor Yellow A protects spinal cords from ischemia/reperfusion injury in rabbits

<p>Abstract</p> <p>Background</p> <p>Hydroxysafflor Yellow A (HSYA), which is one of the most important active ingredients of the Chinese herb <it>Carthamus tinctorius L</it>, is widely used in the treatment of cerebrovascular and cardiovascular diseases. However, the potential protective effect of HSYA in spinal cord ischemia/reperfusion (I/R) injury is still unknown.</p> <p>Methods</p> <p>Thirty-nine rabbits were randomly divided into three groups: sham group, I/R group and HSYA group. All animals were sacrificed after neurological evaluation with modified Tarlov criteria at the 48th hour after reperfusion, and the spinal cord segments (L4-6) were harvested for histopathological examination, biochemical analysis and terminal deoxynucleotidyl transferase-mediated dUTP-biotin nick end labeling (TUNEL) staining.</p> <p>Results</p> <p>Neurological outcomes in HSYA group were slightly improved compared with those in I/R group. Histopathological analysis revealed that HSYA treatment attenuated I/R induced necrosis in spinal cords. Similarly, alleviated oxidative stress was indicated by decreased malondialdehyde (MDA) level and increased superoxide dismutase (SOD) activity after HSYA treatment. Moreover, as seen from TUNEL results, HSYA also protected neurons from I/R-induced apoptosis in rabbits.</p> <p>Conclusions</p> <p>These findings suggest that HSYA may protect spinal cords from I/R injury by alleviating oxidative stress and reducing neuronal apoptosis in rabbits.</p

2,2′-(Imino­dimethyl­ene)dibenz­imid­azol­ium bis­(perchlorate) methanol solvate

In the title compound, C16H17N5 2+·2ClO4 −·CH3OH, the dihedral angle between the two benzimidazolium ring systems is 34.6 (1)°. The anions and solvent mol­ecules are linked to the cation by N—H⋯O hydrogen bonds. In the crystal structure, the combination of N—H⋯O and O—H⋯O hydrogen bonds results in two-dimensional layers running parallel to the (010) plane; these are in turn linked by π–π inter­actions, forming a three-dimensional network