Influence of migration policy risk on international market segmentation: analysis of housing and rental markets in the euro area

This paper aims to discuss the influence of migration policy risk on market segmentation of housing and rental markets in the Euro Area. Policy risk is represented by the Migration Policy Uncertainty Index (MPUI) and Migration Fear Index (MFI) of Germany and the United Kingdom; in this study, whether these indexes influence the interaction between the housing and rental markets of the two countries and euro-area countries was examined. The empirical results showed that the influence of the United Kingdom’s migration policy risk on the euro-area countries is higher than that of Germany. The United Kingdom’s MPUI and MFI significantly contribute to the influence of the United Kingdom’s housing market on other markets except for Belgium and Spain. Compared with housing market connectedness, the rental market connectedness is less influenced by migration policy risk and migration fear. This may be because variables related to short-term residence policies influence the rental market. The high policy risk is more likely to influence decisions related to long-term house purchase, but not those related to short-term residence. Finally, this study found that the higher the uncertainty of the migration policies of the United Kingdom and Germany is, the higher the house market segmentation is

6-Gingerol Inhibits Growth of Colon Cancer Cell LoVo via Induction of G2/M Arrest

6-Gingerol, a natural component of ginger, has been widely reported to possess antiinflammatory and antitumorigenic activities. Despite its potential efficacy against cancer, the anti-tumor mechanisms of 6-gingerol are complicated and remain sketchy. In the present study, we aimed to investigate the anti-tumor effects of 6-gingerol on colon cancer cells. Our results revealed that 6-gingerol treatment significantly reduced the cell viability of human colon cancer cell, LoVo, in a dose-dependent manner. Further flow cytometric analysis showed that 6-gingerol induced significant G2/M phase arrest and had slight influence on sub-G1 phase in LoVo cells. Therefore, levels of cyclins, cyclin-dependent kinases (CDKs), and their regulatory proteins involved in S-G2/M transition were investigated. Our findings revealed that levels of cyclin A, cyclin B1, and CDK1 were diminished; in contrast, levels of the negative cell cycle regulators p27Kip1 and p21Cip1 were increased in response to 6-gingerol treatment. In addition, 6-gingerol treatment elevated intracellular reactive oxygen species (ROS) and phosphorylation level of p53. These findings indicate that exposure of 6-gingerol may induce intracellular ROS and upregulate p53, p27Kip1, and p21Cip1 levels leading to consequent decrease of CDK1, cyclin A, and cyclin B1 as result of cell cycle arrest in LoVo cells. It would be suggested that 6-gingerol should be beneficial to treatment of colon cancer

An appendix adenocarcinoma mimicking appendicitis

SummaryCancer of the appendix is very rare and is typically found incidentally in approximately 1% of patients who received appendectomies. Most of appendiceal tumors are carcinoid, adenoma, and lymphoma. Adenocarcinoma of the appendix accounts for only 10% of all primary appendiceal cancers and the treatment remains controversial. In this article, we report a 67-year-old man who presented with symptoms of appendicitis that was diagnosed as adenocarcinoma of the appendix Stage II. The patient was treated with right hemicolectomy. To date he remains asymptomatic

Swift Observations of the Be/X-ray Transient System 1A 1118-615

We report results of Swift observations for the high mass Be/X-ray binary system 1A 1118-615, during an outburst stage in January, 2009 and at a flaring stage in March, 2009. Using the epoch-folding method, we successfully detected a pulsed period of 407.69(2) sec in the outburst of January and of 407.26(1) sec after the flare detection in March. We find that the spectral detection for the source during outburst can be described by a blackbody model with a high temperature (kT ~ 1-3 keV) and a small radius (R ~ 1 km), indicating that the emission results from the polar cap of the neutron star. On the other hand, the spectra obtained after the outburst can further be described by adding an additional component with a lower temperature (kT ~ 0.1-0.2 keV) and a larger emission radius (R ~ 10-500 km), which indicates the emission from around the inner region of an accretion disk. We find that the thermal emission from the hot spot of the accreting neutron star dominates the radiation in outburst; the existence of both this X-ray contribution and the additional soft component suggest that the polar cap and the accretion disk emission might co-exist after the outburst. Because the two-blackbody signature at the flaring stage is a unique feature of 1A 1118-615, our spectral results may provide a new insight to interpret the X-ray emission for the accreting neutron star. The time separation between the three main outbursts of this system is ~17 years and it might be related to the orbital period. We derive and discuss the associated physical properties by assuming the elongated orbit for this specific Be/X-ray transient.Comment: 9 pages, 3 figures and 4 tables; accepted by MNRA

Bis(imidazo[4,5-f][1,10]phenanthroline)dinitratolead(II)

In the title compound, [Pb(NO3)2(C13H8N4)2], the PbII atom (site symmetry 2) is hexa­coordinated by four N atoms from two N,N′-bidentate imidazo[4,5-f][1,10]phenanthroline (L) ligands and two O atoms from two weakly coordinated nitrate ions [Pb—O = 2.872 (5) Å] in an irregular arrangement, which may be ascribed to the stereochemically active lone pair of electrons on the metal ion. In the crystal, inter­molecular bifurcated N—H⋯(O,O) hydrogen bonds connect the mol­ecules into chains propagating along [100]. Adjacent chains inter­act by strong aromatic π–π stacking inter­actions, with a centroid–centroid distance of 3.483 (2) Å

Stateless Two-Stage Multiple Criteria Scheduling in Nuclear Medicine

Examination in nuclear medicine exhibits scheduling difficulties due to its intricate clinical issues, such as varied radiopharmaceuticals for different diseases, machine preparation and length of scan, and patients’ and hospital’s criteria and/or limitations. Many scheduling methods exist but are limited for nuclear medicine. In this paper, we present stateless two-stage scheduling to cope with multiple criteria decision making. The first stage mostly deals with patients’ conditions. The second stage concerns more the clinical condition and its correlations with patients’ preference which presents more complicated intertwined configurations. A greedy algorithm is proposed in the second stage to determine the (time slot and patient) pair in linear time. The result shows practical and efficient scheduling for nuclear medicine