208 research outputs found
Effects of Volunteering Experiences and Motivations on Attitudes Toward Prisoners: Evidence from Hong Kong
Volunteers are playing an increasingly bigger role in correctional institutions both in Western settings and in the Hong Kong Chinese context, and yet previous studies have focused only on descriptive accounts of their motivation and satisfaction. Utilizing three samples in Hong Kong, namely prison volunteers (N = 54), non-prison volunteers (N = 146), and non-volunteers (N = 77), the present study compares these groups' attitudes toward prisoners. Moreover, this study examines the correlations between volunteer satisfaction and volunteer motivation and attitudes toward prisoners. The results indicate that, compared to the non-volunteer group, both the volunteer groups exhibited more positive attitudes toward prisoners. For the prison volunteers, motivation to express important values and to help others correlated with the attitude that prisoners can change positively. The implications of the study are discussed. © 2012 The Author(s).published_or_final_versio
Juvenile probationers adjudicated of violent and nonviolent offenses in Hong Kong: are they psychologically different?
Part 9: Psychological and Family Factors and CrimeConference Theme: Asian Innovations in Criminology and Criminal JusticeLimited is known about Hong Kong juvenile offenders who are put on probation. This study consists of 109 male juveniles (aged 14-20 years) who served their probation sentence in a community transitional housing. Of the sample, 34 juveniles are adjudicated for committing a violent offense, while the remaining 75 juveniles are found guilty of a nonviolent offense. Six psychometric measures assessing eight psychological correlates (self-esteem, life satisfaction, social bond, positive affect, negative affect,
impulsivity, pro-offending attitudes, and self-perceived life problems) are administered. Four offending history variables (onset age of delinquent behavior, age of first adjudication, number of prior adjudication, and frequency of self-reported delinquency in the past 12 month) are also studied. For exploratory purpose, univariate and bivariate analyses of these two groups (juvenile violent and nonviolent probationers) are first computed. Ordinary Least Square (OLS) regression analyses indicate that several static (offending history) and dynamic (psychological correlates) risk factors are predictors of the juvenile violent and nonviolent probationers’ self-anticipated re-offending risk. Limitations of the study are outlined.postprin
Aortic valve replacement with stentless porcine bioprostheses
Abstractpublished_or_final_versio
Ultrathin films of YBaCuO grown on YSZ substrates with a new buffer layer Nd-Cu-O
YSZ is one of the most widely used substrates to grow oxide superconducting thin films. However, the large lattice mismatch and occurrence of intermediate layer often degrade the quality of grown films. We used a new buffer material, neodymium copper oxide (Nd2 CuO4), to improve the quality of YBCO ultrathin films grown on YSZ. Good superconducting transitions have been obtained on these films with thickness 10-12 nanometers. Such a Nd2CuO 4 layer has a stable crystal structure and behaves as an oxide semiconductor. At 77 K, its resistivity is ~40 times higher than that of PrBaCuO, which has been commonly used as buffer layer and barrier material. The lattice mismatch between Nd2CuO4 and YBCO is much smaller than that between YSZ and YBCO. It allows highly epitaxial growth of YBCO without forming big defects and the intermediate layer. Measurements by using XRD, rocking curve, and cross-sectional TEM indicated that the crystallinity of YBCO films grown on Nd2CuO4 buffer layer had been significantly improved. Besides, the smooth surface of Nd2CuO4 layer and buffered YBCO films are observed by SEM.published_or_final_versio
Factorial structure of the Chinese version of the 12-item General Health Questionnaire in adolescents
Aims. To evaluate the underlying factor structure of the Chinese version of General Health Questionnaire-12 using exploratory and confirmatory factor analyses in Chinese adolescents and find out which factor model proposed by previous empirical research is the best-fit model. Background. The 12-item General Health Questionnaire has been extensively used with adolescents in the West. Yet, it has not been used with adolescents in a Hong Kong Chinese context. Design. A cross-sectional study was employed. Method. Chinese students between the ages of 12-19 from four secondary schools were invited to participate in the study using the multiple-stage stratified random sampling method during the period from December 2007-February, 2008. The total sample size included in the final analysed was 1883. Results. The General Health Questionnaire-12 was found to be internally consistent. The results of exploratory factor analysis showed that there are two factors underlying the General Health Questionnaire-12. Of nine factor models were tested by means of confirmatory factor analysis, only three factor model: the eight-item two-factor model, 12-item three-factor model and 10-item two-factor model, demonstrated good model fit across all model fit indices. Conclusion. This study addressed a gap in the literature by evaluating the factorial structure of the Chinese version of General Health Questionnaire-12 using exploratory and confirmatory factor analyses in Chinese adolescents. The findings revealed that the eight-item two-factor model is the best-fit model. Relevance to clinical practice. The adolescent mental health problem is alarming and aggravating and warrants special attention. It is essential for community nurses to differentiate psychological distress in adolescents and to identify those adolescents who are at a higher risk of suffering from mental health problems. The availability of a valid and reliable instrument that measures adolescents' psychological distress is crucial before any nursing interventions to promote their mental health can be appropriately planned, implemented and evaluated. © 2009 Blackwell Publishing Ltd.postprin
Polarity of influenza H5N1 virus infection in respiratory epithelial cells and the impact of basolateral release of cytokines in disease pathogenesis
Poster Presentations: Virus Host Interaction/PathogenesisINTRODUCTION: Highly pathogenic avian influenza virus (H5N1) is the first avian influenza virus that documented to cause respiratory disease and death in human. The biological basis for the severe human disease and high fatality rate remains unclear. We have previously demonstrated that when compared to human H1N1 and H3N2 influenza viruses, infection of influenza H5N1 virus led to the hyper-induction of pro-inflammatory cytokines in human primary macrophages and ...postprin
Influenza H5N1 virus infection of polarized human alveolar epithelial cells and lung microvascular endothelial cells
Background: Highly pathogenic avian influenza (HPAI) H5N1 virus is entrenched in poultry in Asia and Africa and continues to infect humans zoonotically causing acute respiratory disease syndrome and death. There is evidence that the virus may sometimes spread beyond respiratory tract to cause disseminated infection. The primary target cell for HPAI H5N1 virus in human lung is the alveolar epithelial cell. Alveolar epithelium and its adjacent lung microvascular endothelium form host barriers to the initiation of infection and dissemination of influenza H5N1 infection in humans. These are polarized cells and the polarity of influenza virus entry and egress as well as the secretion of cytokines and chemokines from the virus infected cells are likely to be central to the pathogenesis of human H5N1 disease.Aim: To study influenza A (H5N1) virus replication and host innate immune responses in polarized primary human alveolar epithelial cells and lung microvascular endothelial cells and its relevance to the pathogenesis of human H5N1 disease.Methods: We use an in vitro model of polarized primary human alveolar epithelial cells and lung microvascular endothelial cells grown in transwell culture inserts to compare infection with influenza A subtype H1N1 and H5N1 viruses via the apical or basolateral surfaces.Results: We demonstrate that both influenza H1N1 and H5N1 viruses efficiently infect alveolar epithelial cells from both apical and basolateral surface of the epithelium but release of newly formed virus is mainly from the apical side of the epithelium. In contrast, influenza H5N1 virus, but not H1N1 virus, efficiently infected polarized microvascular endothelial cells from both apical and basolateral aspects. This provides a mechanistic explanation for how H5N1 virus may infect the lung from systemic circulation. Epidemiological evidence has implicated ingestion of virus-contaminated foods as the source of infection in some instances and our data suggests that viremia, secondary to, for example, gastro-intestinal infection, can potentially lead to infection of the lung. HPAI H5N1 virus was a more potent inducer of cytokines (e.g. IP-10, RANTES, IL-6) in comparison to H1N1 virus in alveolar epithelial cells, and these virus-induced chemokines were secreted onto both the apical and basolateral aspects of the polarized alveolar epithelium.Conclusion: The predilection of viruses for different routes of entry and egress from the infected cell is important in understanding the pathogenesis of influenza H5N1 infection and may help unravel the pathogenesis of human H5N1 disease. © 2009 Chan et al; licensee BioMed Central Ltd.published_or_final_versio
A Comparison Between Chinese Children Infected with Coronavirus Disease-2019 and with Severe Acute Respiratory Syndrome 2003
OBJECTIVES: To compare the clinical and laboratory features of severe acute respiratory syndrome 2003 (SARS) and coronavirus disease 2019 (COVID-19) in two Chinese pediatric cohorts, given that the causative pathogens and are biologically similar. , STUDY DESIGN: This is a cross-sectional study reviewing paediatric patients with SARS (n = 43) and COVID-19 (n=244) who were admitted to the Princess Margaret Hospital in Hong Kong and Wuhan Children's Hospital in Wuhan, respectively. Demographics, hospital length of stay, clinical and laboratory features were compared RESULTS: Overall, 97.7% of patients with SARS and 85.2% of patients with COVID-19 had epidemiological associations with known cases. Significantly more patients with SARS developed fever, chills, myalgia, malaise, coryza, sore throat, sputum production, nausea, headache, and dizziness than patients COVID-19. No SARS patients were asymptomatic at the time of admission. 29.1% and 20.9% COVID-19 patients were asymptomatic on admission and throughout their hospital stay, respectively. More SARS patients required oxygen supplementation than COVID-19 patients (18.6 vs. 4.7%, P = 004). Only 1.6% COVID-19 and 2.3% SARS patients required mechanical ventilation. Leukopenia (37.2% vs. 18.6%, p=0.008), lymphopenia (95.4% versus 32.6%, p<0.01), and thrombocytopenia (41.9% vs 3.8%, p<0.001) were significantly more common in SARS than COVID-19 patients. The duration between positive and negative nasopharyngeal aspirate and the length in hospital stay were similar in COVID-19 patients regardless of whether they were asymptomatic or symptomatic, suggesting a similar duration of viral shedding. CONCLUSIONS: Children with COVID-19 were less symptomatic and had more favorable hematological findings than children with SARS
Epidemiology of Acute Myocarditis/Pericarditis in Hong Kong Adolescents Following Comirnaty Vaccination
BACKGROUND: Age-specific incidence of acute myocarditis/pericarditis in adolescents following Comirnaty vaccination in Asia is lacking. This study aimed to study the clinical characteristics and incidence of acute myocarditis/pericarditis among Hong Kong adolescents following Comirnaty vaccination. METHODS: This is a population cohort study in Hong Kong that monitored adverse events following immunization through a pharmacovigilance system for COVID-19 vaccines. All adolescents aged between 12 and 17 years following Comirnaty vaccination were monitored under the COVID-19 vaccine Adverse Event Response and Evaluation Programme. The clinical characteristics and overall incidence of acute myocarditis/pericarditis in adolescents following Comirnaty vaccination were analysed. RESULTS: Between 14 June 2021 and 4 September 2021, 33 Chinese adolescents who developed acute myocarditis/pericarditis following Comirnaty vaccination were identified. 29 (87.88%) were males and 4 (12.12%) were females, with a median age of 15.25 years. 27 (81.82%) and 6 (18.18%) cases developed acute myocarditis/pericarditis after receiving the second and first dose, respectively. All cases are mild and required only conservative management.The overall incidence of acute myocarditis/pericarditis was 18.52 (95% Confidence Interval [CI], 11.67-29.01) per 100,000 persons vaccinated. The incidence after the first and second doses were 3.37 (95%CI 1.12-9.51) and 21.22 (95%CI 13.78-32.28 per 100,000 persons vaccinated, respectively. Among male adolescents, the incidence after the first and second doses were 5.57 (95% CI 2.38-12.53) and 37.32 (95% CI 26.98-51.25) per 100,000 persons vaccinated. CONCLUSIONS: There is a significant increase in the risk of acute myocarditis/pericarditis following Comirnaty vaccination among Chinese male adolescents, especially after the second dose
COVID-19 In Children Across Three Asian Cosmopolitan Regions
As another wave of COVID-19 outbreak has approached in July 2020, a larger scale COVID-19 pediatric Asian cohort summarizing the clinical observations is warranted. Children confirmed with COVID-19 infection from the Republic of Korea, the Hong Kong Special Administrative Region (HKSAR) and Wuhan, China, during their first waves of local outbreaks were included. Their clinical characteristics and the temporal sequences of the first waves of local paediatric outbreaks were compared. Four hundred and twenty three children with COVID-19 were analyzed. Wuhan had the earliest peak, followed by Korea and HKSAR. Compared with Korea and Wuhan, patients in HKSAR were significantly older (mean age: 12.9 vs. 10.8 vs. 6.6 years, p < 0.001, respectively) and had more imported cases (87.5% vs. 16.5% vs. 0%, p < 0.001, respectively). The imported cases were also older (13.4 vs. 7.6 years, p < 0.001). More cases in HKSAR were asymptomatic compared to Korea and Wuhan (45.5% vs. 22.0% vs. 20.9%, p < 0.001, respectively), and significantly more patients from Wuhan developed fever (40.6% vs. 29.7% vs. 21.6%, p=0.003, respectively). There were significantly less imported cases than domestic cases developing fever after adjusting for age and region of origin (p = 0.046). 5.4% to 10.8% of patients reported anosmia and ageusia. None developed pediatric multisystem inflammatory syndrome temporally associated with SARS-CoV-2 (PMIS-TS). In general, adolescents were more likely to be asymptomatic and less likely to develop fever, but required longer hospital stays. In conclusion, majority patients in this pediatric Asian cohort had a mild disease. None developed PIMS-TS. Their clinical characteristics were influenced by travel history and age
- …