8 research outputs found

    Breaking the Silicon Ceiling: Women in Engineering Freshmen Seminar

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    In this paper we describe a pilot study for freshmen women engineering students we launched at the College of Engineering at UMass Amherst in the fall of 2002. This pilot study, which targeted increased retention of women in engineering, was comprised of the following three main elements: a weekly seminar, use of Pocket PCs and a web-based information and exchange center. The students\u27 feedback to our seminar was very positive. The students noted that the seminar allayed their fears and concerns about pursuing engineering, provided a (classroom and online) forum for networking with their peers and other women engineers. This pilot study is the first step in a longitudinal study that will include a series of such seminars as well as follow up assessment provided by the seminar participants throughput the engineering program. We hope that this seminar can serve as a model for women in engineering retention programs and can be deployed at other universities

    Melatonin Ameliorates Coxsackievirus B3-Induced Myocarditis by Regulating Apoptosis and Autophagy

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    Current therapeutics options for viral myocarditis are unsatisfactory. Melatonin (MLT), a hormone secreted by the pineal gland and other organs, has protective effects on ischemic heart injury. However, the potential therapeutic effect of MLT on viral myocarditis is unknown. In this study, we investigated the protective effect of MLT on viral myocarditis in a mouse model of myocarditis infected with coxsackievirus B3 (CVB3) and explored the probable mechanisms. Mice with CVB3-induced myocarditis displayed inflammatory cell infiltration and interstitial edema. MLT treatment significantly ameliorated the myocardial injuries. In addition, the rate of autophagy changed, although apoptosis was inhibited in mouse hearts following treatment with MLT. These results suggest that MLT has a strong therapeutic effect on acute viral myocarditis, which is associated with changes in autophagy and apoptosis in the heart. Thus, MLT could be a promising novel therapeutic approach against viral myocarditis

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