1,813 research outputs found
An efficient approach for shelf space planning and display area allocation in convenience stores
proceedings of the IEEE International Engineering Management Conference, 2009, p. 874-878This paper addresses the problems of shelf space planning and display area allocation in convenience stores. A genetic algorithm is developed to obtain optimum solutions for such problems. A store trial is performed to collect data for analysis and the effects of facing space and display location on product sales are studied. The proposed approach provides a practical and effective means of managing shelf spaces in retail stores. ©2009 IEEE.published_or_final_versio
Dynamic wavelet neural network model for forecasting returns of SHFE copper futures price
Session C8: P13Appropriate forecasting of commodity futures price returns is of crucial importance to achieve hedging effectiveness against the returns volatility risk. This paper presents a nonparametric dynamic recurrent wavelet neural network model for forecasting returns of Shanghai Futures Exchange (SHFE) copper futures price. The proposed model employs a wavelet basis function as the activation function for hidden-layer neurons of the neural network. The aim of this arrangement is to incorporate the fractal properties discovered in futures price return series. In the wavelet transform domain, fractal self-similarity information of the returns series over a certain time scale can be extracted. Input variables are analyzed and selected to facilitate effective forecasting. Statistical indices such as normal mean square error (NMSE) are adopted to evaluate forecasting performance of the proposed model. The forecasted result shows that dynamic wavelet neural network has good prediction properties compared with traditional linear statistical model such as ARIMA and other neural network forecasting models.published_or_final_versionThe 7th International Conference on Digital Enterprise Technology (DET 2011), Athens, Greece, 28-30 September 2011. In Proceedings of the 7th DET, 2011, p. 109-11
Business process modelling in small- to medium-sized enterprises
Data flow analysis is used in a novel context for business process modelling. A framework is presented together with its enterprise modelling concepts and the associated modelling tools. The framework was specifically developed for small- to medium-sized industries. The strengths and weaknesses of the general data flow analysis approach are discussed in terms of its suitability for Hong Kong's small- to medium-sized industries. A case example is also presented to illustrate the methodology.published_or_final_versio
Commodity procurement risk management with futures contracts: a dynamic stack-and-roll approach
Procuring material from commodity spot markets can flexibly fulfil a forward production demand, but increase the risk of high procurement cost due to spot price volatility. In this paper, a dynamic stack-and-roll hedging approach using futures contracts is proposed. The approach aims at mitigating the procurement cost risk and optimising the terminal revenue received from the procurement and hedging activities. It separates the procurement planning horizon into multiple stages, along with varying hedging positions in the nearby futures contracts. Hedging positions are adjusted in response to commodity price behaviour and contemporary perceived information about forward production demand. Guided by the mean-variance criteria over the terminal revenue, dynamic programming is applied to derive a closed-form solution for optimal hedging positions in a discrete-time Markovian setting. Numerical experiments are carried out to assess the proposed approach with explicit solution in a realistic stochastic environment. The price processes are modelled by a fractal nonlinear regression model using real price data of China’s commodity market, while demand information process is modelled by Bayesian formula. The results show that the proposed approach outperforms naive hedging strategy, and effectively mitigates the procurement cost risk.postprin
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The virtual organizing process—A critical tool for enterprise competitiveness in the information era
The term virtual enterprise has generated considerable confusion because of its rather liberal interpretation. This paper argues that the successful establishment of a virtual enterprise is mainly dependent on the virtual organizing processes of an enterprise\u27s strategies ( VOPES), rather than on the actual manifested transformation of the whole into a single virtual organization. A three-dimensional dynamic framework for VOPES is presented, with the aim of providing a coherent model for positioning the various virtual organizing strategies, and at the same time giving VOPES dynamic tendencies towards market negotiation, co-operation, co-ordination and collaboration. To achieve a competitive advantage, the top management of an enterprise operating in an intense information environment can organize their enterprise virtually by using the three-dimensional framework of: virtual customer relationship, virtual outsourcing, and virtual knowledge and expertise. The generic IT architecture of VOPES is also described and discussed
Buy Now and Price Later: Supply Contracts with Time-Consistent Mean-Variance Financial Hedging
We consider a two-stage supply chain comprising one risk-neutral manufacturer (he) and one risk-averse retailer (she), where the manufacturer procures consumption commodities in spot market as major inputs for production and sells the final products to the retailer. The retailer then sells the final products to the market at a stochastic clearance price. We investigate a flexible price contract that allows the manufacturer to determine the product wholesale price, and the retailer to determine the order quantity, based on the future spot price of consumption commodities. Compared with the simple wholesale price contract, a win-win situation can be achieved under the flexible price contract when the manufacturer's postponed processing cost is lower than a threshold. However, under this flexible price contract the retailer may suffer from the commodity price volatility, even if she does not procure the commodities directly. We further investigate how the risk-averse retailer conducts mean-variance financial hedging by purchasing consumption commodity futures contracts. We formulate the problem using a dynamic programming model and derive a closed-form time-consistent financial hedging policy. Through numerical experiments, we show that the commodity price risk from the manufacturer to the retailer is effectively mitigated with the hedging, and the benefits of the flexible price contract are maintained
Prevalence of impacted teeth and associated pathologies - A radiographic study of the Hong Kong Chinese population
Objectives. To investigate the prevalence and pattern of impacted teeth and associated pathologies in the Hong Kong Chinese population. Setting. The Reception and Primary Care Clinic, Prince Philip Dental Hospital, Hong Kong. Design. Retrospective study. Subjects and methods. The records of 7486 patients were examined to determine whether the chief complaints were related to impacted teeth and associated pathologies, which were investigated using panoramic radiographs. Results. A total of 2115 (28.3%) patients presented with at least one impacted tooth. Among the 3853 impacted teeth, mandibular third molars were the most common (82.5%), followed by maxillary third molars (15.6%), and maxillary canines (0.8%). Approximately 8% of mandibular second molars associated with impacted third molars had periodontal bone loss of more than 5 mm on their distal surfaces. Caries were also found on the same surfaces in approximately 7% of the second molars. Approximately 30% of patients with dental impaction had symptoms, and 75% had complaints limited to one side of the mouth. Conclusions. The prevalence of impacted teeth was high, and there was a predilection for impacted third molars in the mandible. More than 50% of maxillary third molars had erupted, creating potential trauma of the pericoronal tissues of the partially erupted mandibular third molars. Caries and periodontal diseases were commonly seen in relation to the impacted third molars, whereas cystic pathology and root resorption were rarely observed.published_or_final_versio
The Endogenous Th17 Response in NO<inf>2</inf>-Promoted Allergic Airway Disease Is Dispensable for Airway Hyperresponsiveness and Distinct from Th17 Adoptive Transfer
Severe, glucocorticoid-resistant asthma comprises 5-7% of patients with asthma. IL-17 is a biomarker of severe asthma, and the adoptive transfer of Th17 cells in mice is sufficient to induce glucocorticoid-resistant allergic airway disease. Nitrogen dioxide (NO2) is an environmental toxin that correlates with asthma severity, exacerbation, and risk of adverse outcomes. Mice that are allergically sensitized to the antigen ovalbumin by exposure to NO2 exhibit a mixed Th2/Th17 adaptive immune response and eosinophil and neutrophil recruitment to the airway following antigen challenge, a phenotype reminiscent of severe clinical asthma. Because IL-1 receptor (IL-1R) signaling is critical in the generation of the Th17 response in vivo, we hypothesized that the IL-1R/Th17 axis contributes to pulmonary inflammation and airway hyperresponsiveness (AHR) in NO2-promoted allergic airway disease and manifests in glucocorticoid-resistant cytokine production. IL-17A neutralization at the time of antigen challenge or genetic deficiency in IL-1R resulted in decreased neutrophil recruitment to the airway following antigen challenge but did not protect against the development of AHR. Instead, IL-1R-/- mice developed exacerbated AHR compared to WT mice. Lung cells from NO2-allergically inflamed mice that were treated in vitro with dexamethasone (Dex) during antigen restimulation exhibited reduced Th17 cytokine production, whereas Th17 cytokine production by lung cells from recipient mice of in vitro Th17-polarized OTII T-cells was resistant to Dex. These results demonstrate that the IL-1R/Th17 axis does not contribute to AHR development in NO2-promoted allergic airway disease, that Th17 adoptive transfer does not necessarily reflect an endogenously-generated Th17 response, and that functions of Th17 responses are contingent on the experimental conditions in which they are generated. © 2013 Martin et al
Molecular identification of adenoviruses associated with respiratory infection in Egypt from 2003 to 2010.
BACKGROUND: Human adenoviruses of species B, C, and E (HAdV-B, -C, -E) are frequent causative agents of acute respiratory infections worldwide. As part of a surveillance program aimed at identifying the etiology of influenza-like illness (ILI) in Egypt, we characterized 105 adenovirus isolates from clinical samples collected between 2003 and 2010. METHODS: Identification of the isolates as HAdV was accomplished by an immunofluorescence assay (IFA) and confirmed by a set of species and type specific polymerase chain reactions (PCR). RESULTS: Of the 105 isolates, 42% were identified as belonging to HAdV-B, 60% as HAdV-C, and 1% as HAdV-E. We identified a total of six co-infections by PCR, of which five were HAdV-B/HAdV-C co-infections, and one was a co-infection of two HAdV-C types: HAdV-5/HAdV-6. Molecular typing by PCR enabled the identification of eight genotypes of human adenoviruses; HAdV-3 (n = 22), HAdV-7 (n = 14), HAdV-11 (n = 8), HAdV-1 (n = 22), HAdV-2 (20), HAdV-5 (n = 15), HAdV-6 (n = 3) and HAdV-4 (n = 1). The most abundant species in the characterized collection of isolates was HAdV-C, which is concordant with existing data for worldwide epidemiology of HAdV respiratory infections. CONCLUSIONS: We identified three species, HAdV-B, -C and -E, among patients with ILI over the course of 7 years in Egypt, with at least eight diverse types circulating
Associations of maternal pre-pregnancy obesity and excess pregnancy weight gains with adverse pregnancy outcomes and length of hospital stay
It is relatively less known whether pre-pregnancy obesity and excess gestational weight gain (GWG) are associated with caesarean delivery, pregnancy complications, preterm birth, birth and placenta weights and increased length of postnatal hospital stay
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