6 research outputs found
Functional Benefit after Modification of Radial Forearm Free Flap for Soft Palate Reconstruction
- Author
- Publication venue
- Korean Society of Otorhinolaryngology-Head and Neck Surgery
- Publication date
- 01/09/2008
- Field of study
ObjectivesTo compare the velopharyngeal function, swallowing and speech of the conventional and modified radial forearm free flap (RFFF) for soft palate reconstruction.MethodsRetrospective clinical study. Twenty-eight patients who underwent oropharyngeal reconstruction with RFFF were divided into two groups: 10 patients had conventional folded RFFF and 18 patients underwent modified method.ResultsThe average speech intelligibility score in modified RFFF group was 8.0±2.4, and 6.2±2.2 in conventional RFFF group (P<0.05). The nasalance was 27.4±7.8% in modified group and 38.6±2.7% in conventional group during no nasal passage reading and 43.6±7.3% in modified group, 55.2±7.6% in conventional group during high nasal passage reading (P<0.05). The subjective swallowing functional score was 2.8 in modified group and 2.1 in conventional group.ConclusionThe speech assessment and nasalance demonstrate a more favorable outcome in modified group than conventional group
Necrotizing Sialometaplasia Accompanied by Adenoid Cystic Carcinoma on the Soft Palate
- Author
- Publication venue
- Korean Society of Otorhinolaryngology-Head and Neck Surgery
- Publication date
- 01/01/2009
- Field of study
Necrotizing Sialometaplasia (NS) is a benign, self-limiting inflammatory disease of the mucus-secreting glands, and this illness mainly involves the minor salivary glands. The significance of NS resides in its clinical and histopathological resemblance to malignancy. We present here a case of necrotizing sialometaplasia on the soft palate, and this was accompanied by adenoid cystic carcinoma. We report here on this case to draw attention to the difficulty for deciding the extent of resecting a malignancy, and especially when the malignancy is simultaneously accompanied by necrotizing sialometaplasia
Enhancement of secreted production of glucoamylase through fed-batch bioreactor culture of recombinant yeast harboring glucose-controllable SUC2 promoter
- Author
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Open data from the first and second observing runs of Advanced LIGO and Advanced Virgo
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- Williams Daniel
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- Willke Benno
- Winkler Walter
- Wipf Christopher C.
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- Woan Graham
- Woehler Janis
- Wofford Jared K.
- Wong Chun-fung
- Wright Jennifer L.
- Wu David S.
- Wysocki Daniel M.
- Xiao Liting
- y J.
- Yamamoto Hiro
- Yang Le
- Yang Yang
- Yang Ziyan
- Yap Min-jet J.
- Yazback Maher
- Yeeles David W.
- Yiqiu Ma
- Yu Hang
- Yu Haocun
- Yuen Shingheirobin
- Zadrozny Adam
- Zadrozny Adam K.
- Zanolin Michele
- Zelenova Tatiana
- Zendri Jean-pierre
- Zevin Michael
- Zhang Jue
- Zhang Liyuan
- Zhang Teng
- Zhao Chunnong
- Zhao Guoying
- Zhou Minchuan
- Zhou Zifan
- Zhu Xingjiang J.
- Zimmerman Aaron B.
- Zucker Michael E.
- Zweizig John
- Publication venue
- 'Elsevier BV'
- Publication date
- 25/12/2019
- Field of study
Advanced LIGO and Advanced Virgo are monitoring the sky and collecting gravitational-wave strain data with sufficient sensitivity to detect signals routinely. In this paper we describe the data recorded by these instruments during their first and second observing runs. The main data products are gravitational-wave strain time series sampled at 16384 Hz. The datasets that include this strain measurement can be freely accessed through the Gravitational Wave Open Science Center at http://gw-openscience.org, together with data-quality information essential for the analysis of LIGO and Virgo data, documentation, tutorials, and supporting software
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)
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- Abdelfatah S
- Abdellatif M
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- Publication venue
- Publication date
- 01/01/2021
- Field of study
In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite numerous reviews, there continues to be confusion regarding acceptable methods to evaluate autophagy, especially in multicellular eukaryotes. Here, we present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes. These guidelines are not meant to be a dogmatic set of rules, because the appropriateness of any assay largely depends on the question being asked and the system being used. Moreover, no individual assay is perfect for every situation, calling for the use of multiple techniques to properly monitor autophagy in each experimental setting. Finally, several core components of the autophagy machinery have been implicated in distinct autophagic processes (canonical and noncanonical autophagy), implying that genetic approaches to block autophagy should rely on targeting two or more autophagy-related genes that ideally participate in distinct steps of the pathway. Along similar lines, because multiple proteins involved in autophagy also regulate other cellular pathways including apoptosis, not all of them can be used as a specific marker for bona fide autophagic responses. Here, we critically discuss current methods of assessing autophagy and the information they can, or cannot, provide. Our ultimate goal is to encourage intellectual and technical innovation in the field