Three-dimensional ultrahigh resolution optical coherence tomography of macular pathologies

purpose. To demonstrate a new generation of three-dimensional (3-D) ultrahigh-resolution optical coherence tomography (UHR OCT) technology for visualization of macular diseases. methods. One hundred forty eyes with a distinct disease in each of the posterior pole compartments were examined with 3-D UHR OCT. 3-D imaging was performed with a high axial resolution of 3 ?m with a compact, commercially available, ultra–broad-bandwidth (160 nm) titanium:sapphire laser at a video rate of up to 25 B-scans/s. Each tomogram consisted of 1024 × 1024 pixels, resulting in 25 megavoxels/s. results. 3-D UHR OCT offers high-precision 3-D visualization of macular diseases at all structural levels. The UHR modality allows identification of the contour of the hyaloid membrane, tractive forces of epiretinal membranes, and changes within the inner limiting membrane. The system provides quality 3-D images of the topographic dynamics of traction lines from the retinal surface down to the level of the photoreceptor segments. Intraretinal diseases are identified by their specific location in different layers of the neurosensory ultrastructure. Photoreceptor inner and outer segments are clearly delineated in configuration and size, with a characteristic peak in the subfoveal area. The microarchitecture of choroidal neovascularization is distinctly imaged, related leakage can be identified, and the volume can be quantified. conclusions. High-speed UHR OCT offers unprecedented, realistic, 3-D imaging of ocular diseases at all epi-, intra- and subretinal levels. A complete 3-D data set of the macular layers allows a comprehensive analysis of focal and diffuse diseases, as well as identification of dynamic pathomechanisms

See the Brain at Work—Intraoperative Laser Doppler Functional Brain Imaging

During open brain surgery we acquire perfusion images non-invasively using laser Doppler imaging. The regions of brain activity show a distinct signal in response to stimulation providing intraoperative functional brain maps of remarkably strong contrast

Der Clown und die Grazie. Zur Transmedialität in Hofmannsthals ›Der Schwierige‹.. Sprachkunst. Beiträge zur Literaturwissenschaft|Sprachkunst XLI / 2010, 1. Halbband|

Telefon, Bild, Salonmusik, vor allem aber der Zirkusclown Furlani: Hofmannsthal inszeniert in >Der Schwierige< eine Fülle intermedialer Verweise und verschärft mit ihnen eine Dichotomie von ,,Sagen" und ,,zeigen". Das ist sowohl Befund als auch Ausweg aus einer modernen Krise der Kommunikation: Das ,,zeigen" delegitimiert in der Komödie zunehmend das ,,Sagen" und bietet die Grazie als altes Konversationsideal neu an: Ausgleich der Dichotomie und Ausdruck beherrschter Transmedialität