Social conditions, hot-spots, and cold-spots of hypertension prevalence rates in Hamburg.

a) unadjusted, b) partially adjusted, c) fully adjusted.</p

Social conditions, hot-spots, and cold-spots of diabetes prevalence rates in Hamburg.

a) unadjusted, b) partially adjusted, c) fully adjusted.</p

Overview of personal level data used in this study.

Overview of personal level data used in this study.</p

Lorenz curves and Gini coefficients for prevalence rates of non-communicable diseases in Hamburg after adjustment for age, gender, education, smoking, alcohol, and social conditions.

Lorenz curves and Gini coefficients for prevalence rates of non-communicable diseases in Hamburg after adjustment for age, gender, education, smoking, alcohol, and social conditions.</p

Administrative structure and local social conditions in Hamburg.

Administrative structure and local social conditions in Hamburg.</p

Social conditions, hot-spots, and cold-spots of COPD prevalence rates in Hamburg.

a) unadjusted, b) partially adjusted, c) fully adjusted.</p

Lifetime prevalence of the analysed NCDs in Hamburg, N = 7,308.

Lifetime prevalence of the analysed NCDs in Hamburg, N = 7,308.</p

Baseline characteristics of the study population, stratified by region/municipalities.

Baseline characteristics of the study population, stratified by region/municipalities.</p

Excerpt results of the logistic regression analyses for the associations of risk factors with NCDs.

Excerpt results of the logistic regression analyses for the associations of risk factors with NCDs.</p

Multi-organ assessment in mainly non-hospitalized individuals after SARS-CoV-2 infection: the Hamburg City Health Study COVID programme

Aims: Long-term sequelae may occur after SARS-CoV-2 infection. We comprehensively assessed organ-specific functions in individuals after mild to moderate SARS-CoV-2 infection compared with controls from the general population.Methods and results: Four hundred and forty-three mainly non-hospitalized individuals were examined in median 9.6 months after the first positive SARS-CoV-2 test and matched for age, sex, and education with 1328 controls from a population-based German cohort. We assessed pulmonary, cardiac, vascular, renal, and neurological status, as well as patient-related outcomes. Bodyplethysmography documented mildly lower total lung volume (regression coefficient -3.24, adjusted P = 0.014) and higher specific airway resistance (regression coefficient 8.11, adjusted P = 0.001) after SARS-CoV-2 infection. Cardiac assessment revealed slightly lower measures of left (regression coefficient for left ventricular ejection fraction on transthoracic echocardiography -0.93, adjusted P = 0.015) and right ventricular function and higher concentrations of cardiac biomarkers (factor 1.14 for high-sensitivity troponin, 1.41 for N-terminal pro-B-type natriuretic peptide, adjusted P ≤ 0.01) in post-SARS-CoV-2 patients compared with matched controls, but no significant differences in cardiac magnetic resonance imaging findings. Sonographically non-compressible femoral veins, suggesting deep vein thrombosis, were substantially more frequent after SARS-CoV-2 infection (odds ratio 2.68, adjusted P Conclusion: Subjects who apparently recovered from mild to moderate SARS-CoV-2 infection show signs of subclinical multi-organ affection related to pulmonary, cardiac, thrombotic, and renal function without signs of structural brain damage, neurocognitive, or quality-of-life impairment. Respective screening may guide further patient management.</div