27,019 research outputs found
Bounds on Information Propagation in Disordered Quantum Spin Chains
We investigate the propagation of information through the disordered XY
model. We find, with a probability that increases with the size of the system,
that all correlations, both classical and quantum, are suppressed outside of an
effective lightcone whose radius grows at most polylogarithmically with |t|.Comment: 4 pages, pdflatex, 1 pdf figure. Corrected the bound for the
localised propagator and quantified the probability it bound occur
Erythropoietin production by fetal mouse liver cells in response to hypoxia and adenylate cyclase stimulation
This study was done to investigate aspects of control of extrarenal erythropoietin (Ep) production. To this end we studied the effects of three stimuli of renal Ep production in the adult, i.e. hypoxia, cobalt, and activation of adenylate cyclase on Ep generation by cultured fetal mouse liver cells. The fetal liver was taken as a model for extrarenal Ep production because this organ is considered the predominant site of extrarenal Ep production. We found that Ep production by the cells increased as the oxygen concentration was decreased in the incubation atmosphere from 20% to 1%. Cobalt (10(-4)-10(-5) M) had no effect on Ep production. Activation of adenylate cyclase by forskolin (10(-5) M) or isoproterenol (10(-5) M) greatly enhanced Ep production. These findings indicate that the Ep-stimulating effect of cobalt is specific for the kidney. However, oxygen depletion and activation of adenylate cyclase seem to be more general stimuli in Ep-producing cells. Furthermore we found that Ep production in hypoxia correlated with lactate formation in the cultured liver cells. This finding suggests that Ep production in fetal livers under hypoxic conditions parallels the shift from aerobic to anaerobic cellular energy metabolism
Optimal Beliefs, Asset Prices, and the Preference for Skewed Returns
Human beings want to believe that good outcomes in the future are more likely, but also want to make good decisions that increase average outcomes in the future. We consider a general equilibrium model with complete markets and show that when investors hold beliefs that optimally balance these two incentives, portfolio holdings and asset prices match six observed patterns: (i) because the cost of biased beliefs are typically second-order, investors typically hold biased assessments of probabilities and so are not perfectly diversified according to objective metrics; (ii) because the costs of biased beliefs temper these biases, the utility costs of the lack of diversification are limited; (iii) because there is a complementarity between believing a state more likely and purchasing more of the asset that pays off in that state, investors over-invest in only one Arrow-Debreu security and smooth their consumption well across the remaining states; (iv) because different households can settle on different states to be optimistic about, optimal portfolios of ex ante identical investors can be heterogeneous; (v) because low-price and low-probability states are the cheapest states to buy consumption in, overoptimism about these states distorts consumption the least in the rest of the states, so that investors tend to overinvest in the most skewed securities; (vi) finally, because investors with optimal expectations have higher demand for more skewed assets, ceteris paribus, more skewed asset can have lower average returns.
Refining self-propelled particle models for collective behaviour
Swarming, schooling, flocking and herding are all names given to the wide variety of collective behaviours exhibited by groups of animals, bacteria and even individual cells. More generally, the term swarming describes the behaviour of an aggregate of agents (not necessarily biological) of similar size and shape which exhibit some emergent property such as directed migration or group cohesion. In this paper we review various individual-based models of collective behaviour and discuss their merits and drawbacks. We further analyse some one-dimensional models in the context of locust swarming. In specific models, in both one and two dimensions, we demonstrate how varying the parameters relating to how much attention individuals pay to their neighbours can dramatically change the behaviour of the group. We also introduce leader individuals to these models with the ability to guide the swarm to a greater or lesser degree as we vary the parameters of the model. We consider evolutionary scenarios for models with leaders in which individuals are allowed to evolve the degree of influence neighbouring individuals have on their subsequent motion
Coarse-grained modelling of supercoiled RNA
We study the behaviour of double-stranded RNA under twist and tension using
oxRNA, a recently developed coarse-grained model of RNA. Introducing explicit
salt-dependence into the model allows us to directly compare our results to
data from recent single-molecule experiments. The model reproduces extension
curves as a function of twist and stretching force, including the buckling
transition and the behaviour of plectoneme structures. For negative
supercoiling, we predict denaturation bubble formation in plectoneme end-loops,
suggesting preferential plectoneme localisation in weak base sequences. OxRNA
exhibits a positive twist-stretch coupling constant, in agreement with recent
experimental observations.Comment: 8 pages + 5 pages Supplementary Materia
Direct numerical simulation of homogeneous nucleation and growth in a phase-field model using cell dynamics method
Homogeneous nucleation and growth in a simplest two-dimensional phase field
model is numerically studied using the cell dynamics method. Whole process from
nucleation to growth is simulated and is shown to follow closely the
Kolmogorov-Johnson-Mehl-Avrami (KJMA) scenario of phase transformation.
Specifically the time evolution of the volume fraction of new stable phase is
found to follow closely the KJMA formula. By fitting the KJMA formula directly
to the simulation data, not only the Avrami exponent but the magnitude of
nucleation rate and, in particular, of incubation time are quantitatively
studied. The modified Avrami plot is also used to verify the derived KJMA
parameters. It is found that the Avrami exponent is close to the ideal
theoretical value m=3. The temperature dependence of nucleation rate follows
the activation-type behavior expected from the classical nucleation theory. On
the other hand, the temperature dependence of incubation time does not follow
the exponential activation-type behavior. Rather the incubation time is
inversely proportional to the temperature predicted from the theory of
Shneidman and Weinberg [J. Non-Cryst. Solids {\bf 160}, 89 (1993)]. A need to
restrict thermal noise in simulation to deduce correct Avrami exponent is also
discussed.Comment: 9 pages, 8 figures, Journal of Chemical Physics to be publishe
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