IMPACTS OF THE FARM FINANCIAL CRISIS: RESULTS OF THE 1989 REGIONAL FARM SURVEY FOR MINNESOTA

Agricultural Finance,

The Monarch Initiative in 2019: an integrative data and analytic platform connecting phenotypes to genotypes across species

In biology and biomedicine, relating phenotypic outcomes with genetic variation and environmental factors remains a challenge: patient phenotypes may not match known diseases, candidate variants may be in genes that haven’t been characterized, research organisms may not recapitulate human or veterinary diseases, environmental factors affecting disease outcomes are unknown or undocumented, and many resources must be queried to find potentially significant phenotypic associations. The Monarch Initiative (https://monarchinitiative.org) integrates information on genes, variants, genotypes, phenotypes and diseases in a variety of species, and allows powerful ontology-based search. We develop many widely adopted ontologies that together enable sophisticated computational analysis, mechanistic discovery and diagnostics of Mendelian diseases. Our algorithms and tools are widely used to identify animal models of human disease through phenotypic similarity, for differential diagnostics and to facilitate translational research. Launched in 2015, Monarch has grown with regards to data (new organisms, more sources, better modeling); new API and standards; ontologies (new Mondo unified disease ontology, improvements to ontologies such as HPO and uPheno); user interface (a redesigned website); and community development. Monarch data, algorithms and tools are being used and extended by resources such as GA4GH and NCATS Translator, among others, to aid mechanistic discovery and diagnostics

Self-protecting motivation, indexed by self-threat, modifies retrieval-induced-forgetting and confidence in employment decision bias against out-group targets

Human memory is malleable by both social and motivational factors and holds information relevant to workplace decisions. Retrieval-induced forgetting (RIF) describes a phenomenon where retrieval practice impairs subsequent memory for related (unpracticed) information. We report two RIF experiments. Chinese participants received a mild self-threat manipulation (Experiment 2) or not (Experiment 1) before an ethnicity-RIF task that involved practicing negative traits of either in-group (Chinese) or an out-group (Japanese) target. After a subsequent memory test, participants selected their preferred applicant for employment. RIF scores correspond to forgetting of unpracticed positive traits of one target (Rp−) relative to the recall of practiced negative traits of the other target (Rp+). Enhanced forgetting of positive traits was found in both experiments for both targets. Across experiments, a significant target by threat interaction showed that target ethnicity modified RIF (an ethnicity-RIF effect). Inducing a self-protecting motivation enhanced RIF effects for the out-group (Japanese) target. In a subsequent employment decision, there was a strong bias to select the in-group target, with the confidence in these decisions being associated with RIF scores. This study suggests that rehearsing negative traits of minority applicants can affect metacognitive aspects of employment decisions, possibly by shaping the schemas available to the majority (in-group) employer. To disrupt systemic racism, recruitment practices should aim to offset a human motivation to protect one-self, when exposed to a relatively mild threat to self-esteem. Discussing the negative traits of minority applicants is a critical, and sensitive, aspect of decision-making that warrants careful practice. These data suggest that recruiting individuals should be reminded of their personal strengths in this context, not their vulnerabilities, to secure their decision-making for fairer recruitment practice

A 'no' with a trace of 'yes':a mouse-tracking study of negative sentence processing

There is strong evidence that comprehenders can parse sentences in an incremental fashion. However, when the sentence contains a negation, the evidence is less clear. Previous work has shown that increasing the pragmatic felicity of a negative sentence reduces or eliminates any processing overhead relative to affirmative sentences. However, in previous work felicity has gone hand-in-hand with the predictability of critical material in a sentence. In three experiments reported here, we presented equally felicitous sentences with critical material of varying predictability (operationalised as the number of possible completions) to test whether this might be a critical factor determining the ease with which partial sentences containing a negation are interpreted. Participants completed a truth-value judgement task (Experiment 1) or a sentence completion task (Experiments 2 and 3) after viewing a visual environment that provided the context for a test sentence, which could differ in truth value (in Experiment 1 only), polarity (affirmative or negative), and number of possible completions (one, two, or three). In all three experiments, we recorded response times and accuracy, but also response dynamics via participants’ computer mouse trajectories, allowing us to test specific hypotheses about the time course of comprehension. Across all experiments, in conditions with one or two possible targets, we observed consistent detrimental effects of negative polarity, suggesting that the difficulty in processing negation cannot be reduced to effects relating to predictability or pragmatic felicity. We discuss this finding in relation to incremental and two-stage models of processing and outline a new account of the processing difficulty arising from negation in terms of a conflict between what is locally activated on the basis of individual words and phrases and the global meaning of a negative sentence

MODELING ANIMAL AND FORAGE RESPONSE TO FERTILIZATION OF ANNUAL RANGELANDS

The response functions for forage, animal gain, and stocking rate were estimated from data obtained in a three-year fertilization experiment on California annual range. Degree-days; the interactions between degree-days and nitrogen, between degree-days and phosphorus-sulphur, and between nitrogen and phosphorus-sulphur; and the lagged forage variable were significant in explaining the variations in forage growth, animal gain, and stocking rate. The impact of PS was more important in interaction with DD or N than by itself. The correct impact of moisture was not found due to misspecification of the variable in the model. The models for the first year and the three years combined were well behaved; however, the models for the last two years combined neither explained adequately nor behaved well.Livestock Production/Industries,

Transfer Effects in Auditory Temporal Preparation Occur Using an Unfilled but not Filled Foreperiod

How quickly participants respond to a “go” after a “warning” signal is partly determined by the time between the two signals (the foreperiod) and the distribution of foreperiods. According to Multiple Trace Theory of Temporal Preparation (MTP), participants use memory traces of previous foreperiods to prepare for the upcoming go signal. If the processes underlying temporal preparation reflect general encoding and memory principles, transfer effects (the carryover effect of a previous block’s distribution of foreperiods to the current block) should be observed regardless of the sensory modality in which signals are presented. Despite convincing evidence for transfer effects in the visual domain, only weak evidence for transfer effects has been documented in the auditory domain. Three experiments were conducted to examine whether such differences in results are due to the modality of the stimulus or other procedural factors. In each experiment, two groups of participants were exposed to different foreperiod distributions in the acquisition phase and to the same foreperiod distribution in the transfer phase. Experiment 1 used a choice-reaction time (RT) task, and the warning signal remained on until the go signal, but there was no evidence for transfer effects. Experiments 2 and 3 used a simple- and choice-RT task, respectively, and there was silence between the warning and go signals. Both experiments revealed evidence for transfer effects, which suggests that transfer effects are most evident when there is no auditory stimulation between the warning and go signals