Models of emission line profiles and spectral energy distributions to characterize the multi-frequency properties of active galactic nuclei

The spectra of Active Galactic Nuclei (AGNs) are often characterized by a wealth of emission lines with different profiles and intensity ratios that led to a complicated classification. Their electro-magnetic radiation spans more than 10 orders of magnitude in frequency. In spite of the differences between various classes, the origin of their activity is attributed to a combination of emitting components, surrounding an accreting Super Massive Black Hole, in the so called Unified Model. Currently, the execution of sky surveys, with instruments operating at various frequencies, provides the possibility to detect and to investigate the properties of AGNs on very large statistical samples. Thanks to the spectroscopic surveys that allow investigation of many objects, we have the opportunity to place new constraints on the nature and evolution of AGNs. In this contribution we present the results obtained by working on multi-frequency data and we discuss their relations with the available optical spectra. We compare our findings with the AGN Unified Model predictions, and we present a revised technique to select AGNs of different types from other line emitting objects. We discuss the multi-frequency properties in terms of the innermost structures of the sources.Comment: 11 pages, 4 figures. Proceedings of the XI Serbian Conference on Spectral Line Shapes in Astrophysics. Accepted for publication on Atom

EGFR Mutations in Indian Lung Cancer Patients: Clinical Correlation and Outcome to EGFR Targeted Therapy

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Stark Broadening of Cr III Spectral Lines: DO White Dwarfs

Using the modified semiempirical method of Dimitrijević and Konjević, Stark widths have been calculated for six Cr III transitions, for an electron density of 10 17 cm ‒ 3 and for temperatures from 5000–80,000 K. Results have been used for the investigation of the influence of Stark broadening on spectral lines in cool DO white dwarf atmospheres. Calculated Stark widths will be implemented in the STARK-B database, which is also a part of the Virtual Atomic and Molecular Data Center (VAMDC)

CRITICAL SHEAR STRESS NEAR BRIDGE PIER FOR NON-UNIFORM SEDIMENTS

This paper describes the main reason of local scour are generally classified into flow condition, structure, and riverbed material used in it and to obtain the simple critical shear stress for the non-uniform sediments. Scouring is significant factor which affects on the safety of bridges. Scouring develops around the pier on the bed channel with non-uniform sediments achieve the great on scour depth prediction. In this a flume experiment has been conducted to predict the relative parameters of shear stress for various size of pier diameter and scour depth using the non-uniform sediments. From the analysis a relationship between shear stress and it’s scour depth may be developed

Frequency of EGFR mutations in 907 lung adenocarcioma patients of Indian ethnicity.

BACKGROUND:During the past decade, the incidence of EGFR mutation has been shown to vary across different ethnicities. It occurs at the rate of 10-15% in North Americans and Europeans, 19% in African-Americans, 20-30% in various East Asian series including Chinese, Koreans, and Japanese. Frequency of EGFR mutations in India however remains sparsely explored. METHODOLOGY/PRINCIPAL FINDINGS:We report 23% incidence of Epidermal growth factor receptor (EGFR) mutations in 907 Non small cell lung cancer (NSCLC) patients of Indian ethnicity, in contrast to 10-15% known in Caucasians and 27-62% among East Asians. In this study, EGFR mutations were found to be more common in never-smokers 29.4% as compared to smokers 15.3%. Consistent with other populations, mutation rates among adenocarcinoma-males were predominantly lower than females with 32% incidence. However unlike Caucasians, EGFR mutation rate among adenocarcinoma-never-smoker females were comparable to males suggesting lack of gender bias among never smokers likely to benefit from EGFR targeted therapy. CONCLUSIONS/SIGNIFICANCE:This study has an overall implication for establishing relevance for routine EGFR mutation diagnostics for NSCLC patients in clinics and emphasizes effectiveness for adoption of EGFR inhibitors as the first line treatment among Indian population. The intermediate frequency of EGFR mutation among Indian population compared to Caucasians and East Asians is reminiscent of an ancestral admixture of genetic influence from Middle Easterners, Central Asians, and Europeans on modern- Indian population that may confer differential susceptibility to somatic mutations in EGFR

Effect of Heat Treatment on Structure of Carbon Shell-Encapsulated Pt Nanoparticles for Fuel Cells

Polymer electrolyte membrane fuel cells (PEMFCs) have attracted much attention as highly efficient, eco-friendly energy conversion devices. However, carbon-supported Pt (Pt/C) catalysts for PEMFCs still have several problems, such as low long-term stability, to be widely commercialized in fuel cell applications. To address the stability issues of Pt/C such as the dissolution, detachment, and agglomeration of Pt nanoparticles under harsh operating conditions, we design an interesting fabrication process to produce a highly active and durable Pt catalyst by introducing a robust carbon shell on the Pt surface. Furthermore, this approach provides insights into how to regulate the carbon shell layer for fuel cell applications. Through the application of an appropriate amount of H2 gas during heat treatment, the carbon shell pores, which are integral to the structure, can be systematically modulated to facilitate oxygen adsorption for the oxygen reduction reaction. Simultaneously, the carbon shell functions as a protective barrier, preventing catalyst degradation. In this regard, we investigate an in-depth analysis of the effects of critical parameters including H2 content and the flow rate of H2/N2 mixed gas during heat treatment to prepare better catalysts

Structure and morphology of the MATLAS dwarf galaxies and their central nuclei

International audienceABSTRACT We present a photometric study of the dwarf galaxy population in the low to moderate density environments of the MATLAS (Mass Assembly of early-Type gaLAxies with their fine Structures) deep imaging survey. The sample consists of 2210 dwarfs, including 508 nucleated. We define a nucleus as a compact source that is close to the galaxy photocentre (within 0.5 $R_\mathrm{ e}$) which is also the brightest such source within the galaxy’s effective radius. The morphological analysis is performed using a 2D surface brightness profile modelling on the g-band images of both the galaxies and nuclei. Our study reveals that, for similar luminosities, the MATLAS dwarfs show ranges in the distribution of structural properties comparable to cluster (Virgo and Fornax) dwarfs and a range of sizes comparable to the Local Group and Local Volume dwarfs. Colour measurements using the r- and i-band images indicate that the dwarfs in low and moderate density environments are as red as cluster dwarfs on average. The observed similarities between dwarf ellipticals in vastly different environments imply that dEs are not uniquely the product of morphological transformation due to ram-pressure stripping and galaxy harassment in high density environments. We measure that the dwarf nuclei are located predominantly in massive, bright and round dwarfs and observe fewer nuclei in dwarfs with a faint centre and a small size. The colour of the galaxy nucleus shows no clear relation to the colour of the dwarf, in agreement with the migration and wet migration nucleus formation scenarios. The catalogues of the MATLAS dwarfs photometric and structural properties are provided