Cronkhite-Canada Syndrome: A Rare Cause of Chronic Diarrhoea in a Young Man

A young Indian man presented with nine-month history of chronic diarrhea, occasionally mixed with blood and intermittent colicky abdominal pain. He also complained of generalized body swelling for the last three months. On examination, he had diffuse hyperpigmentation of the skin and dystrophic nail changes. Upper and lower gastrointestinal endoscopy revealed multiple sessile polyps in the stomach, small bowel, and colon and rectum. Biopsy of polyps showed adenomatous changes with stromal edema and dilated glands. Cronkhite-Canada syndrome (CCS) was diagnosed and treated with glucocorticoids and enteral nutritional supplementation. There was an associated small intestinal bacterial overgrowth (SIBO) and stool was positive for clostridium difficile toxin. After 12 weeks of treatment, the patient achieved remission. Close correlation with clinical findings, including pertinent ectodermal abnormalities, endoscopic studies, and careful examination of biopsies will ensure a timely and correct diagnosis of CCS

An epidemiological study of mortality among mothers admitted in a rural tertiary hospital of West Bengal

Background: Maternal mortality reflects the quality of obstetric services given to pregnant women in the community. Objectives: The objectives of this study were to calculate the maternal mortality rate in a teaching institution, to assess the epidemiological aspects of maternal mortality, and to assess the different causes of maternal mortality. Materials and Methods: This was a retrospective study where individual records of all maternal deaths occurring in our hospital during the past 6 years from 2009 to 2014 were studied. The cause of death and the factors which led to death in each individual case were analyzed. Results: A total of 105 maternal deaths occurred during the study period. The mean maternal mortality ratio in the study period was 233/100,000 live births. Most maternal deaths (37.14%) occurred in the age group of 20–24 years, multiparous women (74.28%) and in women from rural areas (70.47%). Most of the women were unbooked or unregistered patients (64.76%), and 40.95% cases were referred cases. Direct causes accounted for 90.47% of maternal deaths whereas 9.52% of maternal deaths were due to indirect causes. Hemorrhage (26.6%) and eclampsia (27.6%) were the major direct causes of maternal deaths. Conclusion: There is scope for improvement as a large proportion of the observed deaths are preventable. Improving the rural health centers, upgrading the referral centers, and proper transport system is the need of the hour

An epidemiological study of mortality among mothers admitted in a rural tertiary hospital of West Bengal

Background: Maternal mortality reflects the quality of obstetric services given to pregnant women in the community. Objectives: The objectives of this study were to calculate the maternal mortality rate in a teaching institution, to assess the epidemiological aspects of maternal mortality, and to assess the different causes of maternal mortality. Materials and Methods: This was a retrospective study where individual records of all maternal deaths occurring in our hospital during the past 6 years from 2009 to 2014 were studied. The cause of death and the factors which led to death in each individual case were analyzed. Results: A total of 105 maternal deaths occurred during the study period. The mean maternal mortality ratio in the study period was 233/100,000 live births. Most maternal deaths (37.14%) occurred in the age group of 20–24 years, multiparous women (74.28%) and in women from rural areas (70.47%). Most of the women were unbooked or unregistered patients (64.76%), and 40.95% cases were referred cases. Direct causes accounted for 90.47% of maternal deaths whereas 9.52% of maternal deaths were due to indirect causes. Hemorrhage (26.6%) and eclampsia (27.6%) were the major direct causes of maternal deaths. Conclusion: There is scope for improvement as a large proportion of the observed deaths are preventable. Improving the rural health centers, upgrading the referral centers, and proper transport system is the need of the hour

Lymphangioma circumscriptum of the scrotum following vasectomy

Lymphangioma circumscriptum is a congenital lymphatic hamartoma and rarely occurs in the male genital organs. Here we report a case of acquired lymphangioma circumscriptum of scrotum following vasectomy, which has not been reported till date. High clinical suspicion index is the clue to the clinician for diagnosis; histopathological confirmation and adequate surgical excision with deep lymphatic cisterns give the best result

Takayasu’s Arteritis with Systemic Lupus Erythematosus: A Rare Association

We report the case of a 24-year-old nondiabetic, nonhypertensive lady with history of fatigue, dyspnoea and limb claudication. She has been diagnosed with Takayasu’s arteritis. Subsequently she developed rash, alopecia, joint pain, and various other laboratory abnormalities which led to a diagnosis of SLE. Takayasu’s arteritis (TA) rarely coexists with systemic lupus erythematosus (SLE). The absence of specific SLE markers in patients with TA who subsequently develop SLE suggests that the coexistence of these conditions may be coincidental. The antiphospholipid syndrome in patients with SLE may mimic the occlusive vasculitis of TA

Case Report Takayasu's Arteritis with Systemic Lupus Erythematosus: A Rare Association

We report the case of a 24-year-old nondiabetic, nonhypertensive lady with history of fatigue, dyspnoea and limb claudication. She has been diagnosed with Takayasu's arteritis. Subsequently she developed rash, alopecia, joint pain, and various other laboratory abnormalities which led to a diagnosis of SLE. Takayasu's arteritis (TA) rarely coexists with systemic lupus erythematosus (SLE). The absence of specific SLE markers in patients with TA who subsequently develop SLE suggests that the coexistence of these conditions may be coincidental. The antiphospholipid syndrome in patients with SLE may mimic the occlusive vasculitis of TA

Two Uncommon Causes of Guillain-Barré Syndrome: Hepatitis E and Japanese Encephalitis

We are presenting two cases of Guillain-Barré syndrome where it is preceded by hepatitis E virus (HEV) and Japanese encephalitis virus (JEV) infection, respectively. Our first case is a forty-three-year-old nondiabetic, nonhypertensive female who was initially diagnosed with acute HEV induced viral hepatitis and subsequently developed acute onset ascending quadriparesis with lower motor neuron type of bilateral facial nerve palsies and respiratory failure. Second patient was a 14-year-old young male who presented with meningoencephalitis with acute onset symmetric flaccid paraparesis. After thorough investigations it was revealed as a case of Japanese encephalitis. Our idea of reporting these two cases is to make ourselves aware about this potential complication of these two common infections

Exposing the parton-hadron transition within jets with energy-energy correlators in pp collisions at s=5.02\sqrt{\textit s}=5.02 TeV

International audienceThis paper presents a fully-corrected measurement of the energy-energy correlator (EEC) within jets in pp collisions. The EEC traces the energy flow as a highly energetic parton undergoes a QCD shower followed by the confinement of partons into hadrons, probing the correlation function of the energy flow inside jets. The EEC observable is measured as a function of the charged particle pair angular distance, $R_{\rm L}$, for $20 < p_{\rm T}^{\rm ch \, jet} < 80$ GeV/$c$. In the perturbative region (large $R_{\rm L}$), a good agreement between the data and a next-to-leading-log perturbative QCD calculation is observed. In the non-perturbative region (small $R_{\rm L}$), the data exhibits a linear $R_{\rm L}$ dependence. There is a transition region in between, characterized by a turnover in the EEC distribution, corresponding to the confinement process. The peak of this transition region is located at $2.42 \pm 0.17$ GeV/$c/\langle p_{\rm T}^{\rm ch \, jet}\rangle$ for jets of various energies, indicating a common energy scale for the hadronization process. State-of-the-art Monte Carlo event generators are compared with the measurements, and can be used to constrain the parton shower and hadronization mechanisms

Measurement of the inclusive isolated-photon production cross section in pp and Pb−-Pb collisions at sNN=5.02\sqrt{s_{\rm NN}}=5.02 TeV

International audienceThe ALICE Collaboration at the CERN LHC has measured the inclusive production cross section of isolated photons at midrapidity as a function of the photon transverse momentum ($p_{\rm T}^{\gamma}$), in Pb-Pb collisions in different centrality intervals, and in pp collisions, at centre-of-momentum energy per nucleon pair of $\sqrt{s_{\mathrm{NN}}}=5.02$ TeV. The photon transverse momentum range is between 10-14 and 40-140 GeV/$c$, depending on the collision system and on the Pb-Pb centrality class. The result extends to lower $p_{\rm T}^{\gamma}$ than previously published results by the ATLAS and CMS experiments at the same collision energy. The covered pseudorapidity range is $|\eta^{\gamma}| <0.67$. The isolation selection is based on a charged particle isolation momentum threshold $p_{\rm T}^{\rm iso,~ch} = 1.5$ GeV/$c$ within a cone of radii $R=0.2$ and $0.4$. The nuclear modification factor is calculated and found to be consistent with unity in all centrality classes, and also consistent with the HG-PYTHIA model, which describes the event selection and geometry biases that affect the centrality determination in peripheral Pb-Pb collisions. The measurement is compared to next-to-leading order perturbative QCD calculations and to the measurements of isolated photons and Z$^0$ bosons from the CMS experiment, which are all found to be in agreement