Wave Propagation In Water-Saturated Sand And Grain Contact Physics

Measurements in sandy ocean sediments over a broad range of frequencies show that the sound speed dispersion is significantly greater than that predicted by the Biot-Stoll model with constant coefficients, and the observed sound attenuation does not seem to follow a consistent power law. The observations may be explained in terms of the Biot-Stoll model with frequency-dependent complex frame bulk and shear moduli that are governed by the grain-grain contact physics, and random motion at the grain level. In the case of water-saturated sands, the contact stiffness is dominated by squirt flow and viscous drag of a thin fluid film that permeates the contact area. Using this approach, the observed sound and shear wave speeds and attenuations may be modeled over a broad band of frequencies.Applied Research Laboratorie

The Effect Of Roughness On Bottom Loss From Elastic Ocean Bottoms

Acoustic interaction with the ocean bottom profoundly affects propagation in shallow waters. However, most forward ocean bottom interactions are modeled as if the bottom were a flat interface or use a simple model to quantify the additional loss. These assumptions either neglect or over-estimate the enhancement of ocean bottom loss due to scattering into the bottom. Scattering from and into elastic bottoms is particularly interesting since it can induce the production of an interface wave. In this study, finite element analysis is used to calculate acoustic scattering from elastic ocean bottoms with varying degrees of roughness. The forward scattering loss from these bottoms is calculated as a function of angle and then compared with the flat bottom reflection coefficient in order to gain insight on the conditions under which enhancement of bottom loss by rough interface scattering is significant.Applied Research Laboratorie

The Evolution Of Sediment Acoustic Models

Sediment acoustic models contain two connected components, the geo-physical description of the sediment and the model of acoustic processes. Geo-physical descriptors are used in the classification of sediments, and they are based on grain size, density and other physical descriptors. Acoustic sediment models were initially fluid approximations that were simple to implement. As the need for accuracy increased, the fluid model was extended to stratified fluid and visco-elastic models. The latter, with five frequency-independent parameters, appeared to be consistent with sediment acoustic data up to the 1980s. More recent experimental data have revealed discrepancies in the frequency-dependence of attenuation and sound speed, particularly in the case of sandy sediments, which cover a large fraction of the continental shelves. Broad-band acoustic measurements of wave speeds and attenuations are more consistent with a poro-elastic model, consisting of Biot's theory with extensions to account for the physics of granular media. Aside from terminology, there is a fundamental difference between viscoelastic and poro-elastic theories. The former is based on two types of waves, a compressional wave and a shear wave, while the latter has an additional compressional wave, often called the Biot wave. There are currently two approaches to the development of sediment acoustic models: (a) visco-elastic models with frequency dependent parameters that mimic the observed behavior, and (b) poro-elastic models that reflect the physical processes. It is shown that (a) would be a significant improvement over existing models, but (b) is the preferred solution.Applied Research Laboratorie

Inversion of surficial sediment thickness from under-ice acoustic transmission measurement

Author Posting. © Acoustical Society of America, 2021. This article is posted here by permission of Acoustical Society of America for personal use, not for redistribution. The definitive version was published in Journal of the Acoustical Society of America 149(1), (2021): 371, https://doi.org/10.1121/10.0003328.The under-ice acoustic transmission experiment of 2013, conducted under ice cover in the Fram Strait, was analyzed for bottom interactions for the purpose of developing a model of the seabed. Using the acoustic signals, as well as data from other sources, including cores, gravimetric, refraction, and seismic surveys, it was deduced that the seabed may be modeled as a thin surficial layer overlaid on a deeper sediment. The modeling was based on the Biot–Stoll model for acoustic propagation in porous sediments, aided by more recent developments that improve parameter estimation and depth dependence due to consolidation. At every stage, elastic and fluid approximations were explored to simplify the model and improve computational efficiency. It was found the surficial layer could be approximated as a fluid, but the deeper sediment required an elastic model. The full Biot–Stoll model, while instrumental in guiding the model construction, was not needed for the final computation. The model could be made to agree with the measurements by adjusting the surficial layer thickness.The fieldwork was performed under funding from the Research Council of Norway through the UNDER-ICE (Grant No. 226373) project and ENGIE E&P Norway providing additional support. This analysis was supported by the United States Office of Naval Research, Ocean Acoustics Program.2021-07-1

p53 Regulates Oxidative Stress-Mediated Retrograde Signaling: A Novel Mechanism for Chemotherapy-Induced Cardiac Injury

The side effects of cancer therapy on normal tissues limit the success of therapy. Generation of reactive oxygen species (ROS) has been implicated for numerous chemotherapeutic agents including doxorubicin (DOX), a potent cancer chemotherapeutic drug. The production of ROS by DOX has been linked to DNA damage, nuclear translocation of p53, and mitochondrial injury; however, the causal relationship and molecular mechanisms underlying these events are unknown. The present study used wild-type (WT) and p53 homozygous knock-out (p53−/−) mice to investigate the role of p53 in the crosstalk between mitochondria and nucleus. Injecting mice with DOX (20 mg/kg) causes oxidative stress in cardiac tissue as demonstrated by immunogold analysis of the levels of 4-hydroxy-2′-nonenal (4HNE)-adducted protein, a lipid peroxidation product bound to proteins. 4HNE levels increased in both nuclei and mitochondria of WT DOX-treated mice but only in nuclei of DOX-treated p53(−/−) mice, implicating a critical role for p53 in causing DOX-induced oxidative stress in mitochondria. The stress-activated protein c-Jun amino-terminal kinase (JNKs) was activated in response to increased 4HNE in WT mice but not p53(−/−) mice receiving DOX treatment, as determined by co-immunoprecipitation of HNE and pJNK. The activation of JNK in DOX treated WT mice was accompanied by Bcl-2 dissociation from Beclin in mitochondria and induction of type II cell death (autophagic cell death), as evidenced by an increase in LC3-I/LC-3-II ratio and γ-H2AX, a biomarker for DNA damage. The absence of p53 significantly reduces mitochondrial injury, assessed by quantitative morphology, and decline in cardiac function, assessed by left ventricular ejection fraction and fraction shortening. These results demonstrate that p53 plays a critical role in DOX-induced cardiac toxicity, in part, by the induction of oxidative stress mediated retrograde signaling

Estimate of the bottom compressional wave speed profile in the northeastern South China Sea using "Sources of Opportunity"

Author Posting. © IEEE, 2004. This article is posted here by permission of IEEE for personal use, not for redistribution. The definitive version was published in IEEE Journal of Oceanic Engineering 29 (2004): 1231-1248, doi:10.1109/JOE.2004.834681.The inversion of a broad-band "source of opportunity" signal for bottom geoacoustic parameters in the northeastern South China Sea (SCS) is presented, which supplements the towed source and chirp sonar bottom inversions that were performed as part of the Asian Seas International Acoustics Experiment (ASIAEX). This source of opportunity was most likely a "dynamite fishing" signal, which has sufficient low-frequency content (5-500 Hz) to make it complimentary to the somewhat higher frequency J-15-3 towed source (50-260 Hz) signals and the much higher frequency (1-10 kHz) chirp signals. This low frequency content will penetrate deeper into the bottom, thus extending the other inverse results. Localization of the source is discussed, using both a horizontal array for azimuthal steering and the "water wave" part of the pulse arrival for distance estimation. A linear broad-band inverse is performed, and three new variants of the broad-band inverse, based on: 1) the Airy phase; 2) the cutoff frequency; and 3) a range-dependent medium are presented. A multilayer model of the bottom compressional wave speed is obtained, and error estimates for this model are shown, both for the range-independent approximation to the waveguide and for the range-dependent waveguide. Directions for future research are discussed.This work was supported by the Office of Naval Research under Grant N0 001 498-1-0413, Grant N00014-00-0931, and Grant N00014-01-0772 and by the National Science Council, Taiwan, R.O.C. under Grant NSC92-2611-E-002-005-CCS

Axisymmetric wave propagation in multilayered poroelastic grounds due to a transient acoustic point source

International audienceThis paper deals with the study of axisymmetric wave propagation in various acoustic / porous stratified media coupling configurations. It presents the theoretical development of a semi-analytical method, its validation for a limit test-case half-space ground, and an extension to a realistic multilayered seabed, when spherical waves are emitted from a transient point source in water

Seabed characterization using acoustic communication signals on an autonomous underwater vehicle with a thin-line towed array

10.1109/JOE.2012.2227546IEEE Journal of Oceanic Engineering383410-418IJOE