The Use of Fuzzy BackPropagation Neural Networks for the Early Diagnosis of Hypoxic Ischemic Encephalopathy in Newborns

Objective. To establish an early diagnostic system for hypoxic ischemic encephalopathy (HIE) in newborns based on artificial neural networks and to determine its feasibility. Methods. Based on published research as well as preliminary studies in our laboratory, multiple noninvasive indicators with high sensitivity and specificity were selected for the early diagnosis of HIE and employed in the present study, which incorporates fuzzy logic with artificial neural networks. Results. The analysis of the diagnostic results from the fuzzy neural network experiments with 140 cases of HIE showed a correct recognition rate of 100% in all training samples and a correct recognition rate of 95% in all the test samples, indicating a misdiagnosis rate of 5%. Conclusion. A preliminary model using fuzzy backpropagation neural networks based on a composite index of clinical indicators was established and its accuracy for the early diagnosis of HIE was validated. Therefore, this method provides a convenient tool for the early clinical diagnosis of HIE

Study on dynamic characteristics’ change of hippocampal neuron reduced models caused by the Alzheimer’s disease

In the paper, based on the electrophysiological experimental data, the Hippocampal neuron reduced model under the pathology condition of Alzheimer’s disease (AD) has been built by modifying parameters’ values. The reduced neuron model’s dynamic characteristics under effect of AD are comparatively studied. Under direct current stimulation, compared with the normal neuron model, the AD neuron model’s dynamic characteristics have obviously been changed. The neuron model under the AD condition undergoes supercritical Andronov–Hopf bifurcation from the rest state to the continuous discharge state. It is different from the neuron model under the normal condition, which undergoes saddle-node bifurcation. So, the neuron model changes into a resonator with monostable state from an integrator with bistable state under AD’s action. The research reveals the neuron model’s dynamic characteristics’ changing under effect of AD, and provides some theoretic basis for AD research by neurodynamics theory

A New Method for Identifying the Life Parameters via Radar

It has been proved that the vital signs can be detected via radar. To better identify the life parameters such as respiration and heartbeat, a novel method combined with several signal processing techniques is presented. Firstly, to improve the signal-to-noise ratio (SNR) of the life signals, the signal accumulation technique by FFT is used. Then, to restrain the interferences produced by moving objects, a dual filtering algorithm (DFA) which is able to remove the interferences by tracing the interfering spectral peaks is proposed. Finally, the wavelet transform is applied to separate the heartbeat from the respiration signal. The method cannot only help to automatically detect the existence of human beings effectively, but also identifying the parameters like respiration, heartbeat, and body-moving signals significantly. Experimental results demonstrated that the method is very promising in identifying the life parameters via radar

Estimating VDT Mental Fatigue Using Multichannel Linear Descriptors and KPCA-HMM

The impacts of prolonged visual display terminal (VDT) work on central nervous system and autonomic nervous system are observed and analyzed based on electroencephalogram (EEG) and heart rate variability (HRV). Power spectral indices of HRV, the P300 components based on visual oddball task, and multichannel linear descriptors of EEG are combined to estimate the change of mental fatigue. The results show that long-term VDT work induces the mental fatigue. The power spectral of HRV, the P300 components, and multichannel linear descriptors of EEG are correlated with mental fatigue level. The cognitive information processing would come down after long-term VDT work. Moreover, the multichannel linear descriptors of EEG can effectively reflect the changes of θ, α, and β waves and may be used as the indices of the mental fatigue level. The kernel principal component analysis (KPCA) and hidden Markov model (HMM) are combined to differentiate two mental fatigue states. The investigation suggests that the joint KPCA-HMM method can effectively reduce the dimensions of the feature vectors, accelerate the classification speed, and improve the accuracy of mental fatigue to achieve the maximum 88%. Hence KPCA-HMM could be a promising model for the estimation of mental fatigue