Experience of Comamonas Acidovorans Keratitis with Delayed Onset and Treatment Response in Immunocompromised Cornea

summary:We make some comments on the problem of how the Henstock-Kurzweil integral extends the McShane integral for vector-valued functions from the descriptive point of view

Integrated Rocket Simulation of Internal and External Flow Dynamics in an e-Science Environment

The internal and external flowfield variation of a launch vehicle has been simulated in an e-Science environment. To analyze the igniting process of a solid-rocket propellant, a fluid-structure interaction code has been developed using an ALE (arbitrary Lagrangian Eulerian) kinematical description and a staggered fluid-structure interaction algorithm. Also, unsteady motion of a detached rocket booster has been predicted by using an external flow analysis with an aerodynamic-dynamic coupled solver. A Korean e-Science environment designed for aerospace engineering, e-AIRS [15], supplies a user-friendly interface for such individual work and it can advance to an integrated rocket simulation of internal combustion and external flow variation by controlling the execution and data flow of two flow solvers. As a consequence, e-Science facilitates multi-disciplinary collaborative research, and makes individual work more convenient.The current work is a product of the Korea National e-Science project. The authors are grateful to the Korea Institute of Science and Technology Information for their financial support. Also, the authors appreciate the financial supports provided by NSL(National Space Lab.) program through the National Research Foundation of Korea funded by the Ministry of Education, Science and Technology (Grant 20090091724) and the authors are grateful to the Agency for Defence Development for financial support on solid-rocket propellant research.OAIID:oai:osos.snu.ac.kr:snu2009-01/102/0000004648/4SEQ:4PERF_CD:SNU2009-01EVAL_ITEM_CD:102USER_ID:0000004648ADJUST_YN:YEMP_ID:A001138DEPT_CD:446CITE_RATE:1.2FILENAME:article.pdfDEPT_NM:기계항공공학부EMAIL:[email protected]_YN:YCONFIRM:

Neural Dynamics of Olfactory Perception: Low- and High-Frequency Modulations of Local Field Potential Spectra in Mice Revealed by an Oddball Stimulus

Recent brain connectome studies have evidenced distinct and overlapping brain regions involved in processing olfactory perception. However, neural correlates of hypo- or anosmia in olfactory disorder patients are poorly known. Furthermore, the bottom-up and top-down processing of olfactory perception have not been well-documented, resulting in difficulty in locating the disease foci of olfactory disorder patients. The primary aim of this study is to characterize the bottom-up process of the neural dynamics across peripheral and central brain regions in anesthetized mice. We particularly focused on the neural oscillations of local field potential (LFP) in olfactory epithelium (OE), olfactory blub (OB), prefrontal cortex (PFC), and hippocampus (HC) during an olfactory oddball paradigm in urethane anesthetized mice. Odorant presentations evoked neural oscillations across slow and fast frequency bands including delta (1–4 Hz), theta (6–10 Hz), beta (15–30 Hz), low gamma (30–50 Hz), and high gamma (70–100 Hz) in both peripheral and central nervous systems, and the increases were more prominent in the infrequently presented odorant. During 5 s odorant exposures, the oscillatory responses in power were persistent in OE, OB, and PFC, whereas neural oscillations of HC increased only for short time at stimulus onset. These oscillatory responses in power were insignificant in both peripheral and central regions of the ZnSO4-treated anosmia model. These results suggest that olfactory stimulation induce LFP oscillations both in the peripheral and central nervous systems and suggest the possibility of linkage of LFP oscillations in the brain to the oscillations in the peripheral olfactory system

X-SIGMA: XML Based Simple Data Integration System for Gathering, Managing, and Accessing Scientific Experimental Data in Grid Environments

Effective scientific data management is crucial for e-Science applications. Scientific data management raises challenging requirements: (1) support for not only experimental data but also context data, (2) both schema evolution and integration, (3) and compatibility with legacy data management conventions or environments. In this paper, we present a scientific data management system (called X-SIGMA) which is designed to address those issues. X-SIGMA is a Grid-based integrated system for managing, integrating, and accessing scientific experimental data. A prototype system is implemented and has been being used to develop the scientific data management system for the national cyber-infrastructure project called KOCED in Korea

Development of Advanced Cyber Education System Based on Grid

Modern aerodynamics has been revolutionized by computational fluid dynamics (CFD) while most courses are taught with a traditional lecture approach complimented with some combination of homework, labs, and exams. In this paper, we introduce an advanced cyber education system for aerospace engineering, which is named e-AIRS. e-AIRS, an abbreviation of 'e-Science Aerospace Integrated Research System', is a grid based portal system to support the aerodynamics engineering processes on the e-Science environment. The Web portal interface is implemented as aportlet component model on top of the Gridsphere Framework, and these portlets can be reusable. The system provides CFD simulations, remote experimental service, and collaborative and integrative study between computation and experiment through the Web. The system helps students to understand the full simulation process of aerodynamics engineering. We conducted a survey of about 150 students at the Seoul National University and Konkuk University in Korea. According to the survey, 94 percent said the system helped to understand the whole process of CFD, and more than 90 percent of the students said e-AIRS portal provided a good functionality, convenience, and user interface.OAIID:oai:osos.snu.ac.kr:snu2008-01/104/0000004648/56SEQ:56PERF_CD:SNU2008-01EVAL_ITEM_CD:104USER_ID:0000004648ADJUST_YN:NEMP_ID:A001138DEPT_CD:446CITE_RATE:0FILENAME:Development of Advanced Cyber Education System Based on Grid.pdfDEPT_NM:기계항공공학부EMAIL:[email protected]:

CFD Cyber Education Service using Cyberinfrastructure for e-Science

In Korea, prospective college students are increasingly avoiding natural science and engineering. Government is trying to develop an information communication technology (ICT) infrastructure contributed to the encouragement of learner-centered education and to the qualitative enhancement of academic research. It also contributed to the increase in the use of ICT in various areas and to the remarkable improvement in the level of information utilization. In this paper, we introduce a cyber education system for aerospace engineering, which is named e-AIRS. e-AIRS, an abbreviation of e-Science Aerospace Integrated Research System, is a cyber-infrastructure based portal system to support the aerodynamics engineering processes on the e-Science environment. The web portal interface is implemented as a portlet component model on top of the Gridsphere Framework, and these portlets can be reusable. The system provides CFD simulations, remote experimental service, and collaborative and integrative study between computation and experiment through the web. The system helps students to understand the full simulation process of aerodynamics engineering. We conducted a survey of about 150 students at the Seoul National University and Konkuk University in Korea. According to the survey, 94 percent said the system helped to understand the whole process of CFD, and more than 90 percent of the students said e-AIRS portal provided a good functionality, convenience, and user interface.OAIID:oai:osos.snu.ac.kr:snu2008-01/104/0000004648/57SEQ:57PERF_CD:SNU2008-01EVAL_ITEM_CD:104USER_ID:0000004648ADJUST_YN:NEMP_ID:A001138DEPT_CD:446CITE_RATE:0FILENAME:CFD Cyber Education Service using Cyberinfrastructure for e-Science.pdfDEPT_NM:기계항공공학부EMAIL:[email protected]:

CACTUS CFD Toolkit: Combination of Aerodynamic Solver with Advanced Computing Technologies

Cactus[1] is a general-purpose, modular PSE(Problem Solving Environment) designed for scientists and engineers. Since 1995, the base framework has been developed and mainly applied for large scale astrophysics simulations[2]. From those researches, Cactus proved to be a valuable tool for scientific and engineering applications that are tightly coupled, have regular space decomposition, and huge memory and processor time requirements. Currently, Cactus is under the progress of being applied to various studies including CFD(Computational Fluid Dynamics)[3], quantum relativity, chemical reaction and EHD(Electro-Hydro-Dynamics). Especially for CFD simulations, aerodynamicists at 'Seoul National University', 'KISTI Supercomputing Center' and 'KAIST' have been collaborating to make a compressible CFD toolkit working on the Cactus framework. Present paper introduces the current status of a CFD toolkit on the Cactus

Separation Analysis of Strap-ons in the Multi-stage Launch Vehicle Using the Grid Computing Technique

A numerical technique for simulating the separation dynamics of strap-on boosters is presented. Six degree of freedom rigid body equations of motion are integrated into the three-dimensional unsteady Navier-Stokes solution procedure to determine the dynamic motions of strap-ons. An automated Chimera overset mesh technique is introduced to achieve maximum efficiency for the relative motion of multiple bodies and each mesh is constructed as multi-block mesh for the representation of the after-body flow. Additionally, a new computing concept, called the Grid computing technique[1,2], is adopted to guarantee sufficient computing resources and a simple load balancing technique is proposed for an efficient computation in the Grid. As a validation of Chimera mesh technique implementation, computed results around the Titan IV launch vehicle is compared with experimental data and, as a validation of base flow analysis, the aerodynamic coefficients of a strap-on booster of KSR-III is analyzed numerically. The complete analysis process is then applied to the KSR-III, a three-stage sounding rocket researched in Korea. From the analyses, the base flow effect on separation motions of strap-on boosters are investigated and the different aerodynamic characteristics of inviscid and viscous flows at every time interval are examined. In addition, a guidance map of the jettisoning forces and moments for a safe separation is presented from various simulations of separation phenomena with different jettisoning conditions.The authors would like to acknowledge the support from KISTI (Korea Institute of Science and Technology Information) under `The Sixth Strategic Supercomputing Support Program' with Dr. Cho as the technical supporter