The Impact of Reservation Policy on Education in India: An Evaluation of Karnataka's Gram Panchayat Presidency Reservation and Children's Education Attainment for Scheduled Caste and Scheduled Tribe Households

Reservation policy in local governments – Gram Panchayats – in India is one of three key means of affirmative action, ensuring lower caste groups are represented fairly in political institutions. Researchers have found local political reservations for Scheduled Caste (SC) and Scheduled Tribe (ST) populations strongly associated with more SC- and ST-friendly policies, increases in welfare spending and investment in infrastructure, as well as lower household poverty levels. This paper explores one potential indirect benefit of reservations, namely improvements in education attainment. The theory of role model effects is applied to the context of political reservations - greater presence of SC and ST presidents in Gram Panchayats could act as a positive role model of stereotype-defying success for SC and ST children, incentivizing more investment in education attainment. The paper tests the relationship between reservation rates and average completed years of schooling in a dose-response regression model at the sub-district level, using a sample of 13,408 SC children and 6,066 ST children ages 5 to 18 in Karnataka. The results of the analysis suggest that more SC and ST presidents in Gram Panchayats are associated with increases in education attainment among SC and ST children. Further research would be valuable to strengthen these findings and expand the literature on indirect benefits of reservations

Meeting the Moment: New Data on Learning Loss and What We Can Do About It

The Evidence for Gender and Education Resource (EGER) program, under the Population Council’s Girl Innovation, Research, and Learning (GIRL) Center, hosted a virtual webinar titled “Meeting the Moment: New Data on Learning Loss and What We Can Do About It” in October 2021. This document provides a recap of the webinar, in which panelists shared the significant impact of closed schools on learning levels during the COVID-19 pandemic, striking disparities when we intersect poverty, as well as the crucial need to get children back to school and for evidence-based approaches to support learning, such as aligning teaching to the level of the child

From Data to Action: Informing Menstrual Health Management Programs

The Population Council’s Girl Innovation, Research, and Learning (GIRL) Center and Evidence for Gender and Education Resource (EGER) program hosted the second virtual webinar of its From Data to Action series, “Informing Menstrual Health Management Programs” in February 2022. This document provides a recap of the webinar, which featured a global systematic review and results from a randomized controlled trial in Kenya on menstrual health management (MHM) programs. ZanaAfrica shared perspectives on program implementation and how the evidence is shaping their approach

From Data to Action: Partnering with Governments on Evidence to Support Adolescents During the COVID-19 Pandemic

The Population Council’s Girl Innovation, Research, and Learning (GIRL) Center hosted a virtual webinar in October 2021, bringing together evidence from two country-level studies on the impact of the COVID-19 pandemic on adolescent lives in Kenya and Mexico. This document provides a recap of the webinar, in which government partners reflected on the government-research partnership behind these efforts and shared their perspectives on lessons learned and the future of evidence-based policy action to support adolescents

Gendered effects of COVID-19 school closures: India case study

This brief summarizes a case study that assessed the gendered impact of COVID-19 school closures on education, health, well-being, and protection of adolescents in India. Based on surveys and interviews in Bihar and Uttar Pradesh, findings point to the digital divide for girls as well as shared barriers to effective remote learning. Informed by the evidence, the study presents recommendations to scale up efforts to improve remote learning, reduce digital divide and strengthen teacher support, with a particular attention to addressing gendered differences

Gendered effects of COVID-19 school closures: Bangladesh case study

This brief summarizes a recent study on the impacts of COVID-19 school closures in rural communities in Bangladesh. It clarifies issues of remote learning access, management, and monitoring, as well as new strains on students’ time use. It also reveals general impacts on mental and physical health, economic status, as well as gendered effects including child marriage. Based on evaluations of mitigation measures, recommendations for comprehensive policies, provision of technical, financial, and social support, and improvements in education systems emerged

Gendered effects of COVID-19 school closures: Kenya case study

This brief summarizes a case study that assessed the gendered impact of COVID-19 school closures in Kenya. COVID-19 school closures escalated education inequalities especially for girls and young people in rural areas. These closures exacerbated adolescent mental health issues, food and economic insecurity, and experiences of violence. COVID-19 response programs implemented by both the Government of Kenya and non-state actors were not able to fully mitigate the impacts of school closures for adolescents, teachers, or schools. Continued efforts to understand the implications of school closures and to support vulnerable students are needed

Gendered effects of COVID-19 school closures: Pakistan case study

This brief summarizes a case study conducted to assess the gendered impacts of COVID-19 school closures on adolescent girls and boys in three districts in the province of Punjab in Pakistan. Data as well as discussions and interviews with adolescents, teachers, and parents shed light on difficulties in accessing and adjusting to remote learning, learning loss, deterioration of behaviors and health, and other effects. Based on these findings and further reflections by stakeholders on the successes and gaps of mitigation measures, the case study proposes recommendations for improved teacher training, digital access, alternative learning options, and a gendered focus in interventions

Sex specific associations in genome wide association analysis of renal cell carcinoma.

Renal cell carcinoma (RCC) has an undisputed genetic component and a stable 2:1 male to female sex ratio in its incidence across populations, suggesting possible sexual dimorphism in its genetic susceptibility. We conducted the first sex-specific genome-wide association analysis of RCC for men (3227 cases, 4916 controls) and women (1992 cases, 3095 controls) of European ancestry from two RCC genome-wide scans and replicated the top findings using an additional series of men (2261 cases, 5852 controls) and women (1399 cases, 1575 controls) from two independent cohorts of European origin. Our study confirmed sex-specific associations for two known RCC risk loci at 14q24.2 (DPF3) and 2p21(EPAS1). We also identified two additional suggestive male-specific loci at 6q24.3 (SAMD5, male odds ratio (ORmale) = 0.83 [95% CI = 0.78-0.89], Pmale = 1.71 × 10-8 compared with female odds ratio (ORfemale) = 0.98 [95% CI = 0.90-1.07], Pfemale = 0.68) and 12q23.3 (intergenic, ORmale = 0.75 [95% CI = 0.68-0.83], Pmale = 1.59 × 10-8 compared with ORfemale = 0.93 [95% CI = 0.82-1.06], Pfemale = 0.21) that attained genome-wide significance in the joint meta-analysis. Herein, we provide evidence of sex-specific associations in RCC genetic susceptibility and advocate the necessity of larger genetic and genomic studies to unravel the endogenous causes of sex bias in sexually dimorphic traits and diseases like RCC

Genetic Variants Related to Longer Telomere Length are Associated with Increased Risk of Renal Cell Carcinoma.

BACKGROUND: Relative telomere length in peripheral blood leukocytes has been evaluated as a potential biomarker for renal cell carcinoma (RCC) risk in several studies, with conflicting findings. OBJECTIVE: We performed an analysis of genetic variants associated with leukocyte telomere length to assess the relationship between telomere length and RCC risk using Mendelian randomization, an approach unaffected by biases from temporal variability and reverse causation that might have affected earlier investigations. DESIGN, SETTING, AND PARTICIPANTS: Genotypes from nine telomere length-associated variants for 10 784 cases and 20 406 cancer-free controls from six genome-wide association studies (GWAS) of RCC were aggregated into a weighted genetic risk score (GRS) predictive of leukocyte telomere length. OUTCOME MEASUREMENTS AND STATISTICAL ANALYSIS: Odds ratios (ORs) relating the GRS and RCC risk were computed in individual GWAS datasets and combined by meta-analysis. RESULTS AND LIMITATIONS: Longer genetically inferred telomere length was associated with an increased risk of RCC (OR=2.07 per predicted kilobase increase, 95% confidence interval [CI]:=1.70-2.53, p0.5) with GWAS-identified RCC risk variants (rs10936599 and rs9420907) from the telomere length GRS; despite this exclusion, a statistically significant association between the GRS and RCC risk persisted (OR=1.73, 95% CI=1.36-2.21, p<0.0001). Exploratory analyses for individual histologic subtypes suggested comparable associations with the telomere length GRS for clear cell (N=5573, OR=1.93, 95% CI=1.50-2.49, p<0.0001), papillary (N=573, OR=1.96, 95% CI=1.01-3.81, p=0.046), and chromophobe RCC (N=203, OR=2.37, 95% CI=0.78-7.17, p=0.13). CONCLUSIONS: Our investigation adds to the growing body of evidence indicating some aspect of longer telomere length is important for RCC risk. PATIENT SUMMARY: Telomeres are segments of DNA at chromosome ends that maintain chromosomal stability. Our study investigated the relationship between genetic variants associated with telomere length and renal cell carcinoma risk. We found evidence suggesting individuals with inherited predisposition to longer telomere length are at increased risk of developing renal cell carcinoma