50 research outputs found
EFFECT OF VIBRATION APPLICATION INTO DYNAMIC LEG PRESS EXERCISE WITH EXTRA LOAD: MULTI-BODY DYNAMIC ANALYSIS
INTRODUCTION: Many studies have emphasized the importance of resistive exercise in maintaining a healthy human body, particularly in prevention of weakening of physical strength (Kostka, 2002). Recently, some of studies advocated that an application of vibration as a supplementary means in regular training was effective in encouraging physical strength (Annino et al., 2007). Aim of the current study was, therefore, to identify if an application of vibration in a resistive exercise is effective in encouraging physical strength as that in a regular training
Three dimensional inner structure revealed by single particle imaging technique using XFEL
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Rethinking Multi-Object Tracking Based on Re-Identification and Appearance Model Management
Conventional multi-object tracking (MOT) methods often fail to track objects that repeatedly disappear and reappear in the scene due to occlusion or moving off the screen. Previous studies have used motion and appearance information to address these issues but have limitations in dealing with complex scenarios. To overcome these limitations, we propose a post-hoc framework for MOT, a so-called rethinking MOT. The proposed framework efficiently combines MOT and re-identification methods to handle tracking failures in conventional MOT methods. To this end, we proposed a track reliability checking method to determine unreliable tracks and performed re-identification to correct incorrect tracking results. For re-identification, we proposed appearance aspect-ratio matching that is practical and effective. In addition, we designed an online appearance model management for accurate and efficient re-identification. The proposed framework does not require any offline training stages, such as feature or metric learning, but it is very practical for comparing appearances in real time. In addition, it is a flexible and pluggable framework that can adopt any baseline methods for MOT and Re-id. To validate the proposed methods, we collected 12 new challenging indoor datasets. Unlike the existing benchmark MOT datasets, we consider complex indoor sequences where targets reappear many times in the scene. The experimental results reveal that the proposed methods are promising for MOT under various challenging sequences and outperform state-of-the-art methods. Compared to baseline of the proposed rethinking MOT, the score was increased by 36.9% in own dataset and 50.4% in the benchmark dataset
Measurement on spatial coherence in hard x-ray free electron laser apart from the intensity noise and its dependance on the focusing process
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Liver Acinus Dynamic Chip for Assessment of Drug-Induced Zonal Hepatotoxicity
Zonation along the liver acinus is considered a key feature of liver physiology. Here, we developed a liver acinus dynamic (LADY) chip that recapitulates a key functional structure of the liver acinus and hepatic zonation. Corresponding to the blood flow from portal triads to the central vein in vivo, gradual flow of oxygen and glucose–carrying culture medium into the HepG2 cell chamber of the LADY chip generated zonal protein expression patterns in periportal (PP) zone 1 and perivenous (PV) zone 3. Higher levels of albumin secretion and urea production were obtained in a HepG2/HUVECs co-culture LADY chip than in HepG2 mono-culture one. Zonal expression of PEPCK as a PP marker and CYP2E1 as a PV marker was successfully generated. Cell death rate of the PV cells was higher than that of the PP cells since zonal factors responsible for metabolic activation of acetaminophen (APAP) were highly expressed in the PV region. We also found the co-culture enhanced metabolic capacity to process APAP, thus improving resistance to APAP toxicity, in comparison with HepG2 mono-culture. These results indicate that our LADY chip successfully represents liver zonation and could be useful in drug development studies as a drug-induced zonal hepatotoxicity testing platform
Unequivocal observation of electron-induced non-thermal melting process in ATS reflection
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Interhospital Transport System for Critically Ill Patients: Mobile Extracorporeal Membrane Oxygenation without a Ventilator
Background: Extracorporeal membrane oxygenation (ECMO) has been successfully used as a method for the
interhospital transportation of critically ill patients. In South Korea, a well-established ECMO interhospital
transport system is lacking due to limited resources. We developed a simplified ECMO transport system without
mechanical ventilation for use by public emergency medical services. Methods: Eighteen patients utilized
our ECMO transport system from December 2011 to September 2015. We retrospectively analyzed the indications
for ECMO, the patient status during transport, and the patient outcomes. Results: All transport was
conducted on the ground by ambulance. The distances covered ranged from 26 to 408 km (mean, 65.9±88.1
km) and the average transport time was 56.1±57.3 minutes (range, 30 to 280 minutes). All patients were
transported without adverse events. After transport, 4 patients (22.2%) underwent lung transplantation because
of interstitial lung disease. Eight patients who had severe acute respiratory distress syndrome showed
recovery of heart and lung function after ECMO therapy. A total of 13 patients (70.6%) were successfully
taken off ECMO, and 11 patients (61.1%) survived. Conclusion: Our ECMO transport system without mechanical
ventilation can be considered a safe and useful method for interhospital transport and could be a good
alternative option for ECMO transport in Korean hospitals with limited resources
Successful combined second redo lungkidney transplantation in a patient who developed end-stage renal disease after a previous lung transplantation
Several lung transplantation (LTx) patients develop end-stage renal disease (ESRD) and often need a kidney transplant. Recently, the number of multiorgan transplantation cases has increased; however, no successfully combined redo lung-kidney transplantation has been reported in Korea. We present the first case of combined second redo lung-kidney transplantation in a patient with ESRD after LTx. In November 2018, a 40-year-old man with dyspnea was admitted to our hospital. Seventeen years ago, he underwent right pneumonectomy owing to refractory extensive drug-resistant tuberculosis. Four years ago, he underwent left single-LTx due to chronic respiratory failure. He was diagnosed with chronic lung allograft dysfunction and ESRD (glomerular filtration rate, <15). He underwent a second LTx that resulted in acute graft failure. Despite the empirical management, he was not responsive to treatment. He was required to use a home ventilator, but was able to maintain good muscle strength and to walk. However, regular dialysis was required. In January 2019, he underwent combined second redo lung-kidney transplantation and was discharged. At 1-year follow-up, his pulmonary and renal functions were stable without rejection. Combined lung-kidney transplantation could be an effective treatment for selective young patients with respiratory and renal failure who have undergone LTx