Pelatihan dan Pendampingan Pengolahan Kentang Industri pada Kelompok Wanita Tani di Kecamatan Sembalun

This Community Empowerment (PkM) aims to increase partners' knowledge about processing technology for various types of industrial processed potato products, SPP-IRT licensing procedures, packaging and labeling of processed potato products, and business management of processed potato businesses digitally. This activity was attended by 20 participants from the Sembalun and Segara Muncar Women Farmer Groups (KWT). The methods used are lectures, discussions and product processing assistance. The results of the activities show that PkM activities are carried out smoothly, producing a variety of market-ready processed products including bread, potato crunchy strips, pia and potato sticks. Organoleptic test results with 50 consumer panelists stated that the products made were liked, marketable, and had appropriate packaging.Pemberdayaan Masyarakat (PkM) ini bertujuan untuk meningkatkan pengetahuan mitra tentang teknologi pengolahan berbagai jenis produk industri olahan kentang, tata cara perizinan SPP-IRT, pengemasan dan pelabelan produk olahan kentang, serta pengelolaan usaha usaha olahan kentang secara digital. Kegiatan ini diikuti oleh 20 peserta dari Kelompok Wanita Tani (KWT) Sembalun dan Segara Muncar. Metode yang digunakan adalah ceramah, diskusi dan pendampingan pengolahan produk. Hasil kegiatan menunjukkan bahwa kegiatan PkM berjalan lancar, menghasilkan berbagai produk olahan siap pasar antara lain roti, keripik kentang, pia dan stik kentang. Hasil uji organoleptik dengan 50 panelis konsumen menyatakan bahwa produk yang dibuat disukai, dapat dipasarkan, dan memiliki kemasan yang sesuai

Response-adapted radiation therapy for newly diagnosed primary diffuse large B-cell lymphoma of the CNS treated with methotrexate-based systemic therapy

Background: For patients with primary diffuse large B-cell lymphoma of the central nervous system (PCNSL), whole-brain radiation therapy (WBRT) to doses of ≥45 Gy are often given after a partial response (PR) to methotrexate-based induction chemotherapy. We conducted an exploratory analysis to determine whether lower-dose WBRT, given with a boost to sites of persistent disease, might be a reasonable alternative. Methods and materials: We retrospectively reviewed the records of 22 patients with PCNSL who received WBRT, with or without a boost, after methotrexate-based induction chemotherapy. Outcomes were compared among patients according to response to chemotherapy using the Kaplan-Meier method. Results: Median follow-up was 52 months. All patients with a complete response (CR) (n = 5) received WBRT to 23.4 Gy. One CR patient died after an in-field relapse. Patients with partial response (PR) (n = 10) received a median whole-brain dose of 23.4 Gy with (n = 8) or without (n = 2) a boost; there were 2 relapses within the central nervous system (CNS). All PR patients were alive at the time of analysis. The overall survival (P = .127) and freedom from relapse within the CNS (P = .967) were not different for patients with CR versus PR. Baseline and follow-up neurocognitive evaluations were available for 4 PR patients, and there were no significant differences between pre- and post-treatment evaluations (P > .05 for language, memory, visual-spatial, attention, or motor functions). All patients who progressed or did not respond to chemotherapy and then received WBRT had died at a median time of 3.4 months. Patients who progressed or did not respond to chemotherapy had worse overall survival (P = .001) and freedom from CNS relapse (P = .005) compared with CR patients. Conclusions: Among patients with a PR to induction chemotherapy, reduced-dose WBRT with a boost to residual PCNSL may be a viable treatment approach that merits further investigation