3 research outputs found
Protonated chiral prolinamide catalyzed enantioselective direct aldol reaction in water
Protonated chiral prolinamide organocatalysts have been shown to catalyze an enantioselective direct aldol process in water to provide the aldol product in high yield and good enantioselectivity. The two diastereomeric catalysts (S,R)-4b and (S,S)-4c show different reactivity. © 2005 Elsevier Ltd. All rights reserved