これからの女性のキャリアと社会参画 ―安田女子大学現代ビジネス学会の15周年記念事業―

　現代ビジネス学会設立15周年事業として、2018年10月27日土曜日、国際会議場を会場に開催された講演会・シンポジウム「これからの女性のキャリアと社会参画-誰もが生き生きと輝ける社会を目指して」の報告書である

平成28年度教育改革研究助成シミュレーション学習（４要素融合学習）の試みについて～導入２年目の教育改革～

本稿は、シミュレーション学習（４要素融合学習）導入２年目の取組みに関する報告書である。本取組みの概要、並びに、その成果として、（1）コース選択制の理解度向上への対策、（2）コース別目標の見直し、（3）カリキュラムの見直しについて、の３点を指摘している。引き続き、シミュレーション学習の深化、充実化のために、努める所存である

Decreased circulating branched-chain amino acids are associated with development of Alzheimer’s disease in elderly individuals with mild cognitive impairment

BackgroundNutritional epidemiology has shown that inadequate dietary protein intake is associated with poor brain function in the elderly population. The plasma free amino acid (PFAA) profile reflects nutritional status and may have the potential to predict future changes in cognitive function. Here, we report the results of a 2-year interim analysis of a 3-year longitudinal study following mild cognitive impairment (MCI) participants.MethodIn a multicenter prospective cohort design, MCI participants were recruited, and fasting plasma samples were collected. Based on clinical assessment of cognitive function up to 2 years after blood collection, MCI participants were divided into two groups: remained with MCI or reverted to cognitively normal (“MCI-stable,” N = 87) and converted to Alzheimer’s disease (AD) (“AD-convert,” N = 68). The baseline PFAA profile was compared between the two groups. Stratified analysis based on apolipoprotein E ε4 (APOE ε4) allele possession was also conducted.ResultsPlasma concentrations of all nine essential amino acids (EAAs) were lower in the AD-convert group. Among EAAs, three branched-chain amino acids (BCAAs), valine, leucine and isoleucine, and histidine (His) exhibited significant differences even in the logistic regression model adjusted for potential confounding factors such as age, sex, body mass index (BMI), and APOE ε4 possession (p < 0.05). In the stratified analysis, differences in plasma concentrations of these four EAAs were more pronounced in the APOE ε4-negative group.ConclusionThe PFAA profile, especially decreases in BCAAs and His, is associated with development of AD in MCI participants, and the difference was larger in the APOE ε4-negative population, suggesting that the PFAA profile is an independent risk indicator for AD development. Measuring the PFAA profile may have importance in assessing the risk of AD conversion in the MCI population, possibly reflecting nutritional status.Clinical trial registration[https://center6.umin.ac.jp/cgi-open-bin/ctr/ctr_view.cgi?recptno=R000025322], identifier [UMIN000021965]

保健師学生の関わりからみたB地区自主防災活動の課題

B地区における8年間の保健師学生の防災活動の取り組みについて分析し、地域の自主防災活動の課題を明らかにした。①学生が作成した既存資料等の分析、②防災対策関係者と学生の意見交換、③2町内における防災講習会の実施と自主防災活動への意識調査、④防災対策関係者への聞き取り調査を行った。その結果、①リーダーの積極的かつ先駆的な働きかけのもとに、町内単位やコミュニティセンター活動を活かして自主防災活動の啓発を行う。②時間の経過とともに防災意識が薄れる中で学生が継続的に介入し、地域の防災行動の普及・啓発を図る。③専門職や他地区の自主防災組織等と連携、協働の上、自主防災組織の繋がりをさらに強化する