Effect of change in body mass index on morbidity in non-obese university graduates.

To establish the actual serial changes in body weight in Japanese people and to elucidate the influence of changes in BMI on morbidity, we conducted a historical cohort study of university graduates from 1955 to 1990 using questionnaires and BMI data. The subjects of this study were 3,675 university graduates aged 26-62 years in whom BMI was determined at the time of enrollment in the university (Pre-BMI), 5 to 40 years earlier. Morbidity (one or more system diseases or obesity-related system diseases) was analyzed according to current age, sex, current BMI, deltaBMI (difference between current BMI and pre-BMI), and various lifestyle variables. The proportion of overweight subjects at enrollment to university was higher in recent male students compared to old students, but not in female graduates, and the BMI in both genders increased progressively after graduation, especially in recent male graduates. Pre-BMI correlated negatively and significantly with deltaBMI. The percentages of obese (BMI > or = 30 kg/m2) males and females were 1.6% and 0.5%, respectively, and high morbidity was observed in 56.1% and 42.2% of males and females, respectively. Stepwise regression analysis showed that in subjects with normal BMI at enrollment, prospective morbidity was dependent on ABMI in addition to age. Our results indicate that in subjects with normal body weight, prospective morbidity is determined by increment of ABMI, and suggest that maintenance of BMI at the late adolescence level is an important factor in preventing future disease.</p

Results from the Japan 2016 report card on physical activity for children and youth

Background: The Report Card on Physical Activity for Children and Youth aims to consolidate existing evidence, encourage more evidence-informed physical activity, and improve surveillance of physical activity. Methods: Application of Canada and Scotland Report Card methodology to Japan, adapted to Japanese circumstances and availability of data, and based on nationally representative surveys. Results: The 2016 Japan Report Card on Physical Activity for Children and Youth consists of Health Behaviors and Outcomes (7 indicators); and Influences on Health Behaviors (4 indicators). Three Health Behaviors and Outcomes received C grades (Participation in Sport; Sedentary Behavior; Recreational Screen Time; Physical Fitness), while two indicators could not be graded (Overall Physical Activity, and Active Play). The indicators Active Transportation (B) and Weight Status were favorable (A). In the Influences domain, Family Influence and Community and the Built Environment were graded as D, while the School & Childcare Settings and the Government Strategies and Investments were favorable (B). Conclusions: The Japan report card illustrated some favorable health behaviors, health outcomes, and influences. There is a need for more evidence especially on overall physical activity, active play, and community and the built environment

RBM10 in complete hydatidiform mole: cytoplasmic occurrence of its 50 kDa polypeptide

Background: RNA-binding motif protein 10 (RBM10), originally identified as S1-1 protein, is a nuclear protein with likely functions in transcription and RNA splicing. The RBM10 gene maps to the X chromosome and, in female cells, is inactivated in one of the two X chromosomes near the boundary with genes escaping inactivation. This study investigated the occurrence of the RBM10 gene product in complete hydatidiform mole, which is composed of cells with paternal diploid chromosomes (46, XX).Methods: Deparaffinized normal chorion or complete hydatidiform mole tissues were hybridized with a fluorescein-conjugated RBM10 gene probe in fluorescent in situ hybridization (FISH) analysis. Immunohistochemistry and immunoelectron microscopy of the tissues were performed using an anti-RBM10 antiserum. Proteins from complete hydatidiform mole tissues and those separated by anti-RBM10-linked affinity chromatography were also examined by western blotting.Results: As expected, the RBM10 gene was detected by FISH as double spots in the nuclei of complete hydatidiform mole cells. Immunohistochemistry revealed a nuclear presence of RBM10 in normal chorion and complete hydatidiform moles, and a notable cytoplasmic presence in complete hydatidiform moles. Western blotting and immunoaffinity chromatography revealed that a 50 kDa protein was predominantly found in the cytosolic fraction of complete hydatidiform moles.Conclusions: A 50 kDa protein with common antigenicity to RBM10 was found in the cytoplasm of complete hydatidiform mole cells, and could represent one of the characteristics of the disease

母性看護学実習における産後電話訪問への取り組みと学習効果

母性看護学実習において、産後電話訪間を実施し実施方法と学生の学習効果を評価した。対象は2007年4月～2008年12月の間、母性看護学実習を行い同意の得られた113名の学生である。アンケートでの自己評価を全体、実施群、未実施群に分けた比較と、学びのレポートの内容から検討した。結果、実習方法では、実施手順を示した配布資料は有効活用されていた。学習効果として退院後の生活のイメージ化、退院後の心身健康状態の把握、退院時の個別問題の明確化につながった。一方で、実施群に比べ未実施群では学びの広がりが見られにくいため、スタッフとの意見交換の場を設けるなど実習方法の改善が必要である

出産前教室が夫の対児感情及び育児動機に及ぼす影響 : 乳児とその親との関わりの有無による比較

乳児とその親との関わりの有無に着目し、出産前教室が初産婦の夫の対児感情や育児動機に及ぼす影響を明らかにするため、出産前教室に夫婦で参加した初産婦の夫57名に対し、教室前後でアンケート調査を行った。結果、出産前教室受講前に比べ後は、接近得点と育児動機得点が上昇し、拮抗指数が低下した。また出産前教室における乳児参加教室と乳児不参加教室で比較したところ、乳児不参加教室よりも乳児参加教室の回避感情と拮抗指数が低下していた。これらのことから、出産前教室の受講は初産婦の夫が親となる心の準備を整えるために効果的であり、さらに乳児とその親と関わることは乳児への否定的感情を低下させることが示唆された