2,872 research outputs found
Lepton Flavor Violating Decays of Neutral Higgses in Extended Mirror Fermion Model
We perform the one-loop induced charged lepton flavor violating decays of the
neutral Higgses in an extended mirror fermion model with non-sterile
electroweak-scale right-handed neutrinos and a horizontal symmetry in the
lepton sector. We demonstrate that for the 125 GeV scalar there is tension
between the recent LHC result 1% and the
stringent limits on the rare processes and
or from low energy experiments.Comment: 23 pages, 3 figures. Added some of referenc
Multilepton Higgs Decays through the Dark Portal
The U(1)_D gauge sector containing one dark Higgs boson h_D and one dark
photon \gamma_D may be explored through the decays of the 126 GeV particle
discovered at the Large Hadron Collider (LHC), assumed here as the heavier mass
eigenstate h_1 in the mixing of the standard model h with h_D. The various
decays of h_1 to \gamma_D \gamma_D, h_2 h_2, h_2 \gamma_D \gamma_D and h_2 h_2
h_2 would yield multilepton final states through the mixing of \gamma_D with
the photon and the decay h_2 \to \gamma_D \gamma_D, where h_2 is the lighter
dark Higgs. Future searches for signals of multilepton jets at the LHC may
reveal the existence of this possible dark sector governed simply by the
original Abelian Higgs model.Comment: 20 pages, 9 figures, 2 tables. New section added for signals of
multilepton jets at the LHC-1
DISPEL: Domain Generalization via Domain-Specific Liberating
Domain generalization aims to learn a generalization model that can perform
well on unseen test domains by only training on limited source domains.
However, existing domain generalization approaches often bring in
prediction-irrelevant noise or require the collection of domain labels. To
address these challenges, we consider the domain generalization problem from a
different perspective by categorizing underlying feature groups into
domain-shared and domain-specific features. Nevertheless, the domain-specific
features are difficult to be identified and distinguished from the input data.
In this work, we propose DomaIn-SPEcific Liberating (DISPEL), a post-processing
fine-grained masking approach that can filter out undefined and
indistinguishable domain-specific features in the embedding space.
Specifically, DISPEL utilizes a mask generator that produces a unique mask for
each input data to filter domain-specific features. The DISPEL framework is
highly flexible to be applied to any fine-tuned models. We derive a
generalization error bound to guarantee the generalization performance by
optimizing a designed objective loss. The experimental results on five
benchmarks demonstrate DISPEL outperforms existing methods and can further
generalize various algorithms
Towards Fair Patient-Trial Matching via Patient-Criterion Level Fairness Constraint
Clinical trials are indispensable in developing new treatments, but they face
obstacles in patient recruitment and retention, hindering the enrollment of
necessary participants. To tackle these challenges, deep learning frameworks
have been created to match patients to trials. These frameworks calculate the
similarity between patients and clinical trial eligibility criteria,
considering the discrepancy between inclusion and exclusion criteria. Recent
studies have shown that these frameworks outperform earlier approaches.
However, deep learning models may raise fairness issues in patient-trial
matching when certain sensitive groups of individuals are underrepresented in
clinical trials, leading to incomplete or inaccurate data and potential harm.
To tackle the issue of fairness, this work proposes a fair patient-trial
matching framework by generating a patient-criterion level fairness constraint.
The proposed framework considers the inconsistency between the embedding of
inclusion and exclusion criteria among patients of different sensitive groups.
The experimental results on real-world patient-trial and patient-criterion
matching tasks demonstrate that the proposed framework can successfully
alleviate the predictions that tend to be biased
Classifying TIM Barrel Protein Domain Structure by an Alignment Approach Using Best Hit Strategy and PSI-BLAST
Sarcoma of the Larynx: Treatment Results and Literature Review
BackgroundSarcomas of the larynx are rare neoplasms that constitute less than 1% of laryngeal malignancies. A Medline search found no large series focusing on laryngeal sarcomas. We reviewed the cases of laryngeal sarcomas treated in our cancer center and compared our experiences and treatment results with those from other centers.MethodsA retrospective review of 10 patients with laryngeal sarcoma treated in our institute between 1980 and 2000 was done to identify tumor characteristics, therapeutic modalities, and treatment outcomes.ResultsThe patients showed a male predominance (9/10) and presented 8 types of pathology. Nine patients underwent surgery, including 2 total laryngectomy, 4 partial laryngectomy, and 3 endoscopic laser cordectomy. During a median follow-up of 92 months, the 5-year overall survival and disease-specific survival were 76% and 90%, respectively. Two patients developed recurrence, including 1 local recurrence and 1 distant metastasis.ConclusionSurgical intervention was the first choice in the treatment of laryngeal sarcomas. The prognosis is relatively good when compared with sarcoma originating from other anatomic sites
Small B cell lymphocytic lymphoma presenting as obstructive sleep apnea
BACKGROUND: Most lymphomas that involve the tonsil are large B cell lymphomas. Large B-cell lymphoma is a high grade malignancy which progresses rapidly. Tonsillar lymphoma usually presents as either a unilaterally enlarged palatine tonsil or as an ulcerative and fungating lesion over the tonsillar area. Small lymphocytic lymphomas (SLL) of the Waldeyer's ring are uncommon. CASE PRESENTATION: We report a 41-year-old male who presented with a ten-year history of snoring. Physical examination revealed smooth bilateral symmetrically enlarged tonsils without abnormal surface change or cervical lymphadenopathy. Palatal redundancy and a narrowed oropharyngeal airway were also noted. The respiratory disturbance index (RDI) was 66 per hour, and severe obstruction sleep apnea (OSA) was suspected. No B symptoms, sore throat, odynophagia or dysphagia was found. We performed uvulopalatopharyngoplasty (UPPP) and pathological examination revealed incidental small B-cell lymphocytic lymphoma (SLL). CONCLUSION: It is uncommon for lymphoma to initially present as OSA. SLL is an indolent malignancy and is not easy to detect in the early stage. We conclude that SLL may be a contributing factor of OSA in the present case
Phase-controlled vibrational laser percussion drilling
In this study, a phase-controlled vibration was applied to a laser percussion drilling process to improve the depth of penetration. To investigate the effects of phase-controlled vibration on the depth of penetration, a novel method that controls the phase offset between the accelerating motion and the emission of the laser beam was developed. The method is based on coaxial sensing of the working surface using a photodiode, coupled with microcontroller control of the drilling laser operation. Through real-time optical signal acquisition and analysis of laser machining processes, correlations between the accelerating motion and the emission of the laser beam were simultaneously obtained. All of the processing work was performed in air at standard atmospheric conditions, and gas assist was not used. This study showed that the application of phase-controlled vibration improved the depth of penetration in laser percussion machining and can contribute to the development of precision drilling in the industry
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