Acute exacerbation of psychiatric symptoms during influenza treatment with oseltamivir in chronic schizophrenia

AbstractInfluenza treatment and prophylaxis with oseltamivir are critically important in reducing the morbidity and mortality of patients in chronic psychiatric facilities. Abnormal behavior, delusions, perceptual disturbances, mania, and depression have all been reported as oseltamivir-related psychiatric side effects. We hereby report two chronic schizophrenia patients in Taiwan manifesting psychiatric instability who were being treated with oseltamivir for suspected influenza infection, and further discuss other potential contributing factors. The possibility that oseltamivir can cause psychotic or affective symptoms suggests that additional caution is necessary for its use in patients with an established psychiatric diagnosis

Association Between Type I and II Diabetes With Gallbladder Stone Disease

Objective: To assess the association of type 1 diabetes (T1DM) and type 2 diabetes (T2DM) with the subsequent development of gallbladder stone disease (GSD).Setting: Cohort Study.Participants: We identified two study cohort groups to evaluate the association of T1DM and T2DM with the development of GSD. The first group comprised a T1DM cohort of 7015 patients aged ≤ 40 years and a non-diabetes cohort randomly matched with the study cohort (4:1). The second group comprised a T2DM cohort of 51,689 patients aged ≥20 years and a non-diabetes cohort randomly matched with the study cohort (1:1). All patients were studied from 1996 to the end of 2011 or withdrawal from the National Health Insurance program to determine the incidence of GSD.Results: Compared with patients without diabetes, those with T1DM had a decreased risk of GSD [adjusted hazard ratios (aHR) = 0.48, 95% confidence interval (CI) = 0.25–0.92]. Those with T2DM had an increased risk of GSD (aHR = 1.55, 95% CI = 1.41–1.69), after adjustment for age, sex, comorbidities, and number of parity. The relative risk of GSD in the T2DM cohort was higher than that in the non-diabetes cohort in each group of age, sex, and patients with or without comorbidity. However, the relative risk of GSD in the T1DM cohort was lower than that in the non-diabetes cohort only in the age group of 20–40 years.Conclusion: Our population-based cohort study reveals a strong association between T2DM and GSD. However, an inverse relationship exists between T1DM and GSD in patients aged 20–40 years

Transformer-based Image Compression with Variable Image Quality Objectives

This paper presents a Transformer-based image compression system that allows for a variable image quality objective according to the user's preference. Optimizing a learned codec for different quality objectives leads to reconstructed images with varying visual characteristics. Our method provides the user with the flexibility to choose a trade-off between two image quality objectives using a single, shared model. Motivated by the success of prompt-tuning techniques, we introduce prompt tokens to condition our Transformer-based autoencoder. These prompt tokens are generated adaptively based on the user's preference and input image through learning a prompt generation network. Extensive experiments on commonly used quality metrics demonstrate the effectiveness of our method in adapting the encoding and/or decoding processes to a variable quality objective. While offering the additional flexibility, our proposed method performs comparably to the single-objective methods in terms of rate-distortion performance

Semantic Segmentation Using Super Resolution Technique as Pre-Processing

Combining high-level and low-level visual tasks is a common technique in the field of computer vision. This work integrates the technique of image super resolution to semantic segmentation for document image binarization. It demonstrates that using image super-resolution as a preprocessing step can effectively enhance the results and performance of semantic segmentation

Efficacy of Sanfujiu to Treat Allergies: Patient Outcomes at 1 Year after Treatment

Sanfujiu is a treatment method of applying herbal paste onto the acupoints Fengmen and Feishu during the three hottest days of summer to treat patients with allergies. The objectives of this study were to determine the treatment efficacy at 1 year after the Sanfujiu treatment, and examine variations in the perceived efficacy of Sanfujiu among different subgroups, based on the patients' ages, diagnoses and number of reactive symptoms immediately after the treatment. We enrolled 105 patients who completed Sanfujiu treatment at a medical university hospital in Taipei as the subjects. One year after treatment, trained interviewers conducted telephone interviews with the patients. Approximately 60% of them perceived the treatment as being effective at 1 year later, which was higher than that at 1 week after treatment (45.7%). Younger subjects (<19 years of age) and patients with asthma were more likely to report the treatment as being effective. Patients who had more reactive symptoms after the third Sanfujiu treatment were more likely to report the treatment as being effective. The results demonstrated that Sanfujiu was moderately effective, as perceived by patients in Taiwan, in treating their allergic symptoms

Full HD JPEG XR Encoder Design for Digital Photography Applications

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