11 research outputs found
Ba ancaloit khung indol từ cây trang nam (Kopsia pitardii Merr.)
Three monoterpenoid indole alkaloids: methyl 11, 12-methylenedioxy-N1-decarbomethoxy-∆14,15-chanofruticosinate (1), methyl N1-decarbomethoxychanofruticosinate (2), methyl 11,12-methylenedioxychanofruticosinate (3) were isolated from dried leaves of the Vietnamese medicinal plant Trang-Nam (Kopsia pitardii Merr., Apocynaceae) with 0.12, 0.038 and 0.005% yields, respectively. Their structures were determined by MS and NMR means
Thành phần hóa học dịch chiết etyl axetat cây bảy lá một (Paris polyphylla var. chinensis Franchet) trồng tại Việt Nam
Phytochemical investigation of the ethyl acetate extract of Paris polyphylla var. chinensis Franchet led to the isolation of 6 compounds, including stigmasterol (1), pennogenin (2), quercetin (3), (+)-trans-ε-viniferin (4), diosgenin-3-O-α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside (ophiopogonin C’, 5), and diosgenin-3-O-α-L-rhamnopyranosyl-(1→2)-[β-D-glucopyranosyl-(1→3)]-β-D-glucopyranoside (gracillin, 6). Their structures were elucidated by 1D, 2D-NMR spectra, HR-ESI-MS and APCI-MS, and in comparison with reported data. Keywords. Paris polyphylla var. chinensis, gracillin, pennogenin, ophiopogonin C’, spirostan steroid
Tổng hợp một số dẫn xuất của cycloart-23z-ene-3β-25-diol và hoạt tính sinh học của chúng
Chemical constituents of Xerospermum laevigatum Radlk = Nghiên cứu thành phần hóa học của Xerospermum laevigatum Radlk
Tổng hợp một số dẫn xuất của Lupeol và nghiên cứu hoạt tính kháng vi sinh vật kiểm định
The lupane triterpenoid lupeol is found in a variety of plants. Its biological activities have attracted a great deal of interests. A number of studies on the antiinflammatory, antimycobacterial, antimalarial and anticancer activities of this compound and its derivatives have been reported. Based on our knowledge, there have not been any reports on the antimicrobial activity of lupeol and its derivatives. In order to investigate the relationship between the chemical structure and antimicrobial activities, several derivatives of lupeol, such as lupeol acetate, lupeol isobutyrate, lupeol benzoate and lupeol cinnamate were synthesized, and the antibacterial and antifungal effects of these derivatives were examined. It was found that these derivatives possessed only weak antimicrobial activities, and that the above acylation of the OH group at C-3 did not lead to an improvement of the antibacterial and anti-fungal activities