95 research outputs found

    Survey on public attitude and perception towards ethnic minorities 2004

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    Oxfam Hong Kong commissioned Asia-Pacific Institute of Ageing Studies (APIAS), Lingnan University to conduct a telephone survey and concealed participatory observation in order to recognize the public (Hong Kong people) attitude and perception towards ethnic minorities. Telephone numbers were selected at random from up-to-date residential phone directories and the target population of the study comprised Chinese speaking male and female adults aged 16 or over. The telephone interviews were conducted on 4 and 5 of August 2004 from 6:00pm to 10:00pm. 512 interviews were completed from the randomly chosen 917 households, and the response rate was 55.8%. Results are subject to a maximum sampling error (MSE) of ±4.3 % at the 95% confidence level. The questionnaire is divided into seven parts with 33 items, including Hong Kong people’s attitudes and perceptions towards ethnic minorities in areas of work and employment, education, utilization of public services, rent and accommodation, friendship and marriage, general perception and the sources of perception formation. A concealed participatory observation was conducted in August 2004 with the aim of understanding the actual employment situation of ethnic minorities in Hong Kong and recognizing whether racial background would be a cause for not being offered job interviews and opportunities. Two female Hong Kong residents with age 19 and similar socio-economic background were employed; one of them is originated from Pakistanis and can speak fluent Cantonese with some Pakistanis accent, the other one is a native Chinese. Both of them applied 50 identical jobs through the Labour Department’s web sites. All of them were elementary occupations in 5 broad categories, including clerk, service employee workers, shop sales worker, office assistant and promoter

    Rice Hypersensitive Induced Reaction Protein 1 (OsHIR1) associates with plasma membrane and triggers hypersensitive cell death

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    <p>Abstract</p> <p>Background</p> <p>In plants, HIR (Hypersensitive Induced Reaction) proteins, members of the PID (Proliferation, Ion and Death) superfamily, have been shown to play a part in the development of spontaneous hypersensitive response lesions in leaves, in reaction to pathogen attacks. The levels of HIR proteins were shown to correlate with localized host cell deaths and defense responses in maize and barley. However, not much was known about the HIR proteins in rice. Since rice is an important cereal crop consumed by more than 50% of the populations in Asia and Africa, it is crucial to understand the mechanisms of disease responses in this plant. We previously identified the rice HIR1 (OsHIR1) as an interacting partner of the OsLRR1 (rice Leucine-Rich Repeat protein 1). Here we show that OsHIR1 triggers hypersensitive cell death and its localization to the plasma membrane is enhanced by OsLRR1.</p> <p>Result</p> <p>Through electron microscopy studies using wild type rice plants, OsHIR1 was found to mainly localize to the plasma membrane, with a minor portion localized to the tonoplast. Moreover, the plasma membrane localization of OsHIR1 was enhanced in transgenic rice plants overexpressing its interacting protein partner, OsLRR1. Co-localization of OsHIR1 and OsLRR1 to the plasma membrane was confirmed by double-labeling electron microscopy. Pathogen inoculation studies using transgenic <it>Arabidopsis thaliana </it>expressing either OsHIR1 or OsLRR1 showed that both transgenic lines exhibited increased resistance toward the bacterial pathogen <it>Pseudomonas syringae </it>pv. <it>tomato </it>DC3000. However, <it>OsHIR1 </it>transgenic plants produced more extensive spontaneous hypersensitive response lesions and contained lower titers of the invading pathogen, when compared to <it>OsLRR1 </it>transgenic plants.</p> <p>Conclusion</p> <p>The OsHIR1 protein is mainly localized to the plasma membrane, and its subcellular localization in that compartment is enhanced by OsLRR1. The expression of OsHIR1 may sensitize the plant so that it is more prone to HR and hence can react more promptly to limit the invading pathogens' spread from the infection sites.</p

    An exploratory study on the significance of outbound travelling for the older persons in Hong Kong

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    Hong Kong has been experiencing demographic ageing with an increasing number of older population and prolonged life expectancy. It is projected that population will increase from 12% in 2004 to 24% in 2031 (Census and Statistics Department of Hong Kong, 2002). Older people in the future are expected to be wealthier and healthier and the potential demand for recreational activities will strongly be associated with this group. As highlighted in the Chief Executive of the HKSAR 2001 policy address, the future direction of elderly care and services is to improve the quality of life of older persons, ensuring that they will continue to enjoy a sense of security, belonging and a feeling of good health and worthiness. The report on healthy ageing by the Elderly Commission suggested that promoting physical well-being alone is not enough for older people and therefore a number of ways to enhance their psychological well-being are necessary (Elderly Commission, 2001). The importance of psychological well-being to quality of life of older people and their life expectancy is an integral part of the concept of successful ageing and also forms a main plank in the WHO’s policy framework of active ageing (WHO, 2002). More active social participation or leisure activities are very widely recognized as crucial. According to reports published by the Hong Kong Tourist Association (HKTA, 1998), Hong Kong residents departures to overseas destinations increased from 3.4 million in 1996 to 3.8 million in 1997, representing a growth rate of 9.1%. Although the trend for older people in Hong Kong is not clear from literature and existing data, outbound travelling for older people seems to be a development which is both commercially viable and probably socially desirable. A popular activity to enhance the quality of life of older people in Hong Kong is outbound travelling. The “graying” of population in Hong Kong has aroused the attention of people running overseas tourism and it is not surprising that given the increasing number of older people and the large amount of unoccupied time available to them, this has captured the interest of those examining travel characteristics of the market (Van Harssel, 1994). Indeed, many people identified by demographic age as “elderly” may be cognitively young (Schiffman & Sherman, 1991) and open to innovation in their travel behaviour (Szmigin & Carrigan, 2001). Moreover, in all likelihood, older tourists will be as strongly motivated to travel as younger people (Sharpley, 1994). Thereby, senior travel is becoming a widely recognized aspect for promoting healthy and active ageing. However, the research conducted in Hong Kong concerning the meaning and significance of outbound travelling amongst older people in Hong Kong has been very limited so far. The present research presents an exploratory study on senior travel in the context of Hong Kong and four dimensions are addressed as follows: The motivations for outbound travelling amongst older people in Hong Kong. The perceived barriers to outbound travelling amongst older people in Hong Kong. To describe and analyze the travel modes and activities conducted during outbound travel. To explore the psychological meaning(s) of outbound travel for older people

    A report on an exploratory study on visual conditions of older people living in public housing

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    HOPE worldwide (HWW) has been a chartered charity organization in Hong Kong since 1993, with its focus on organizing service programmes in China and Hong Kong. Volunteers for Seniors Day (formerly Hope for Seniors Day) is one of the many programmes initiated by HWW to meet the urgent needs of the growing ageing population in Hong Kong. Starting in 1996, volunteers from corporations and social organizations have been recruited for Volunteers for Seniors Days on an annual basis. Since 2000, the programme has been jointly organized with the Housing Authority to provide cleaning and painting services to single elderly tenants living in public housing estates. It also helps to build relationships between the volunteers and the elderly people in the community. Over the past nine years, the programme has served over 5,300 single elderly people and mobilized more than 20,000 volunteers to participate. In the survey conducted by HWW during Volunteers for Seniors Day 2004, we found that there were up to 40.1% and 49.6% of the single elderly living in public housing estates suffering from various kinds of eye diseases and poor eyesight respectively. The prevalence of eye diseases and poor eyesight would result in a high percentage of falls and thereby affect their functional activities of daily living (ADL). In fact, most of the eye diseases are curable with early detection and treatment, and elderly people with poor eyesight may need minor home adaptation e.g. handrails or night lights to prevent home accidents. According to a study by the Department of Orthopaedics & Traumatology of Chinese University, exercise is important to the elderly and can strengthen their low-limb and upper-limb muscles, which in turn prevents falls at home or on the street. Due to the above findings, HWW cooperated with Housing Authority to initiate a pilot programme to help identify the eye diseases as well as provide public health education to the elderly in 30 public estates in the second half of 2004. Health care professionals provided training to 150 volunteers on eye care knowledge and simple eye screening tests that could be carried out in road shows in shopping arcades of public housing estates. In addition, experienced ophthalmologists or optometrists were present to answer elderly participants’ inquiries on eye health and delivered health information during the kick-off ceremony and road shows in the shopping arcades. The programme had the following objectives: To enhance the awareness of eye health and eye diseases of the elderly through 30 public eye screenings at public housing arcades; To carry out a survey on the visual conditions of elderly living in public housing; and To foster partnership between government, NGO and business sectors in promoting the health of the elderly in the community

    Immunoregulatory Protein Profiles of Necrotizing Enterocolitis versus Spontaneous Intestinal Perforation in Preterm Infants

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    Necrotizing enterocolitis (NEC) and spontaneous intestinal perforation (SIP) are the most common acute surgical emergencies associated with high morbidity and mortality in preterm infants. We aimed to compare the profiles of immunoregulatory proteins and identify novel mediators in plasma of NEC and SIP infants. We also investigated the expression of target genes in resected intestinal tissues and an enterocyte cell line. Using Cytokine Antibody Array assay, we reported the first comparative profiles of immunoregulatory proteins in plasma of NEC and SIP infants, and showed that dysregulated proteins belonged to functionally diversified categories, including pro- and anti-inflammation, angiogenesis, cell growth, wound healing, anti-apoptosis, cell adhesion and extracellular matrix reorganization. Validation by ELISA confirmed significantly higher concentrations of interleukin (IL)-6, angiopoietin (Ang)-2, soluble type II interleukin-1 receptor (sIL-1RII), and soluble urokinase-type plasminogen activator receptor (suPAR) in NEC infants compared with gestational age-matched control, and a lower level of an epidermal growth factor receptor, secreted form of receptor tyrosine-protein kinase ErbB3 (sErbB3), compared with SIP infants. mRNA expressions of IL1-RII and uPAR were up-regulated in resected bowel tissues from NEC infants, indicating that immunoregulation also occurred at the cellular level. In FHs-74 Int cells, Ang-2, IL1-RII and uPAR mRNA expressions were significantly induced by the combined treatment with lipopolysaccharide (LPS) and platelet activating factor (PAF). Our study provided plasmatic signatures of immunoregulatory proteins in NEC and SIP infants, and demonstrated involvement of multiple functional pathways. The magnitude of changes in these proteins was significantly more extensive in NEC infants, reflecting the different nature of injury and/or severity of inflammation. We speculate that dysregulation of IL-6, Ang-2, IL-1RII and uPAR occurred at both systemic and cellular levels, and probably mediated via LPS and endogeneous PAF signals. Such exaggerated immunologic responses may account for the high morbidity and mortality in NEC compared with SIP patients

    Happy farming programme : an exploratory study from an intergenerational perspective

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    Background: To extend the successful experience learnt from the Golden Organic Farming Programme in Tsuen Wan organized by Produce Green Foundation in 2004, a new farming programme entitled “Happy Farming” has been launched in Tuen Mun. A plot of land was leased to Good Tiding Church of Christian National’s Evangelism Commission in Lai Wai Tuen Mun (屯門泥圍佳音福音堂) by the Government. APIAS was invited to design and implement the farming programme in January 2005. Nine volunteers were recruited, including five older people and four youngsters to work together on farming activities including land exploitation, trainings, ploughing, weeding and mass activities such as opening day and harvest day so that intergenerational cooperation and communication could be promoted. By the experience where joint effort is needed, it is expected that the intergenerational programme could bring a certain amount of happiness to the participants. Objectives: In order to get a better understanding of the ways farming activities could enhance happiness of the participants and promote intergenerational relationships, an exploratory study on the impacts of farming will be investigated. To make it more specific, the research objectives are addressed as follows: To explore the way(s) of intergenerational cooperations and communications during farming activities; To investigate the association of farming activities towards the increase in happiness of the participants (the old and the young); To identify an effective programme intervention strategy to promote intergenerational support and psychological well-being (happiness) for policy makers

    Mindfulness-based cognitive therapy v. group psychoeducation for people with generalised anxiety disorder: randomised controlled trial

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    Background: Research suggests that an 8-week mindfulness-based cognitive therapy (MBCT) course may be effective for generalised anxiety disorder (GAD). Aims: To compare changes in anxiety levels among participants with GAD randomly assigned to MBCT, cognitive–behavioural therapy-based psychoeducation and usual care. Method: In total, 182 participants with GAD were recruited (trial registration number: CUHK_CCT00267) and assigned to the three groups and followed for 5 months after baseline assessment with the two intervention groups followed for an additional 6 months. Primary outcomes were anxiety and worry levels. Results: Linear mixed models demonstrated significant group × time interaction (F(4,148) = 5.10, P = 0.001) effects for decreased anxiety for both the intervention groups relative to usual care. Significant group × time interaction effects were observed for worry and depressive symptoms and mental health-related quality of life for the psychoeducation group only. Conclusions: These results suggest that both of the interventions appear to be superior to usual care for the reduction of anxiety symptoms

    Career and life development intervention for non-engaged youth: Evaluating the Hong Kong Benchmarks (Community) Pilot Program

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    In our study, aimed at examining the effectiveness and impact of the Hong Kong Benchmarks (Community) Pilot Program, a career and life development (CLD) intervention program targeting non-engaged youth (NEY) in Hong Kong, we employed a pretest–posttest quasi-experimental design to compare changes in career-related competencies between a pilot group (N = 289) and a comparison group (N = 160). We also conducted five focus group interviews with the leaders of nongovernmental organizations, social workers, NEY, parents, and employers to explore the program’s impacts on the CLD service provisions. Our quantitative results indicate that the piloting group showed greater improvement in two career-related competencies—youth career development competency and career and life development hope—than the comparison group. Meanwhile, our qualitative results suggest both the benefits and difficulties experienced by stakeholders in the program. The findings thus provide preliminary evidence of the Hong Kong Benchmarks (Community) Pilot Program’s positive impacts on NEY and other important stakeholders. The implications of expanding the existing program and theorizing the community-based benchmark approach are also discussed

    Host factors do not influence the colonization or infection by fluconazole resistant Candida species in hospitalized patients

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    Nosocomial yeast infections have significantly increased during the past two decades in industrialized countries, including Taiwan. This has been associated with the emergence of resistance to fluconazole and other antifungal drugs. The medical records of 88 patients, colonized or infected with Candida species, from nine of the 22 hospitals that provided clinical isolates to the Taiwan Surveillance of Antimicrobial Resistance of Yeasts (TSARY) program in 1999 were reviewed. A total of 35 patients contributed fluconazole resistant strains [minimum inhibitory concentrations (MICs) ≧ 64 mg/l], while the remaining 53 patients contributed susceptible ones (MICs ≦ 8 mg/l). Fluconazole resistance was more frequent among isolates of Candida tropicalis (46.5%) than either C. albicans (36.8%) or C. glabrata (30.8%). There was no significant difference in demographic characteristics or underlying diseases among patients contributing strains different in drug susceptibility
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