Strength training reduces arterial blood pressure but not sympathetic neural activity in young normoten- sive subjects

. Strength training reduces arterial blood pressure but not sympathetic neural activity in young normotensive subjects. J Appl Physiol 94: 2212-2216, 2003. First published January 31, 2003 10.1152/japplphysiol. 01109.2002The effects of resistance training on arterial blood pressure and muscle sympathetic nerve activity (MSNA) at rest have not been established. Although endurance training is commonly recommended to lower arterial blood pressure, it is not known whether similar adaptations occur with resistance training. Therefore, we tested the hypothesis that whole body resistance training reduces arterial blood pressure at rest, with concomitant reductions in MSNA. Twelve young [21 Ϯ 0.3 (SE) yr] subjects underwent a program of whole body resistance training 3 days/wk for 8 wk. Resting arterial blood pressure (n ϭ 12; automated sphygmomanometer) and MSNA (n ϭ 8; peroneal nerve microneurography) were measured during a 5-min period of supine rest before and after exercise training. Thirteen additional young (21 Ϯ 0.8 yr) subjects served as controls. Resistance training significantly increased one-repetition maximum values in all trained muscle groups (P Ͻ 0.001), and it significantly decreased systolic (130 Ϯ 3 to 121 Ϯ 2 mmHg; P ϭ 0.01), diastolic (69 Ϯ 3 to 61 Ϯ 2 mmHg; P ϭ 0.04), and mean (89 Ϯ 2 to 81 Ϯ 2 mmHg; P ϭ 0.01) arterial blood pressures at rest. Resistance training did not affect MSNA or heart rate. Arterial blood pressures and MSNA were unchanged, but heart rate increased after 8 wk of relative inactivity for subjects in the control group (61 Ϯ 2 to 67 Ϯ 3 beats/min; P ϭ 0.01). These results indicate that whole body resistance exercise training might decrease the risk for development of cardiovascular disease by lowering arterial blood pressure but that reductions of pressure are not coupled to resistance exercise-induced decreases of sympathetic tone

The glassy response of solid He-4 to torsional oscillations

We calculated the glassy response of solid He-4 to torsional oscillations assuming a phenomenological glass model. Making only a few assumptions about the distribution of glassy relaxation times in a small subsystem of otherwise rigid solid He-4, we can account for the magnitude of the observed period shift and concomitant dissipation peak in several torsion oscillator experiments. The implications of the glass model for solid He-4 are threefold: (1) The dynamics of solid He-4 is governed by glassy relaxation processes. (2) The distribution of relaxation times varies significantly between different torsion oscillator experiments. (3) The mechanical response of a torsion oscillator does not require a supersolid component to account for the observed anomaly at low temperatures, though we cannot rule out its existence.Comment: 9 pages, 4 figures, presented at QFS200

Glide and Superclimb of Dislocations in Solid 4^4He

Glide and climb of quantum dislocations under finite external stress, variation of chemical potential and bias (geometrical slanting) in Peierls potential are studied by Monte Carlo simulations of the effective string model. We treat on unified ground quantum effects at finite temperatures $T$. Climb at low $T$ is assisted by superflow along dislocation core -- {\it superclimb}. Above some critical stress avalanche-type creation of kinks is found. It is characterized by hysteretic behavior at low $T$. At finite biases gliding dislocation remains rough even at lowest $T$ -- the behavior opposite to non-slanted dislocations. In contrast to glide, superclimb is characterized by quantum smooth state at low temperatures even for finite bias. In some intermediate $T$-range giant values of the compressibility as well as non-Luttinger type behavior of the core superfluid are observed.Comment: Updated version submitted to JLTP as QFS2010 proceedings; 11 pages, 6 figure

Superfluidity of a perfect quantum crystal

In recent years, experimental data were published which point to the possibility of the existence of superfluidity in solid helium. To investigate this phenomenon theoretically we employ a hierarchy of equations for reduced density matrices which describes a quantum system that is in thermodynamic equilibrium below the Bose-Einstein condensation point, the hierarchy being obtained earlier by the author. It is shown that the hierarchy admits solutions relevant to a perfect crystal (immobile) in which there is a frictionless flow of atoms, which testifies to the possibility of superfluidity in ideal solids. The solutions are studied with the help of the bifurcation method and some their peculiarities are found out. Various physical aspects of the problem, among them experimental ones, are discussed as well.Comment: 24 pages with 2 figures, version accepted for publication in Eur.Phys.J.

Classification of a supersolid: Trial wavefunctions, Symmetry breakings and Excitation spectra

A state of matter is characterized by its symmetry breaking and elementary excitations. A supersolid is a state which breaks both translational symmetry and internal $U(1)$ symmetry. Here, we review some past and recent works in phenomenological Ginsburg-Landau theories, ground state trial wavefunctions and microscopic numerical calculations. We also write down a new effective supersolid Hamiltonian on a lattice. The eigenstates of the Hamiltonian contains both the ground state wavefunction and all the excited states (supersolidon) wavefunctions. We contrast various kinds of supersolids in both continuous systems and on lattices, both condensed matter and cold atom systems. We provide additional new insights in studying their order parameters, symmetry breaking patterns, the excitation spectra and detection methods.Comment: REVTEX4, 19 pages, 3 figure

A glassy contribution to the heat capacity of hcp 4^4He solids

We model the low-temperature specific heat of solid $^4$He in the hexagonal closed packed structure by invoking two-level tunneling states in addition to the usual phonon contribution of a Debye crystal for temperatures far below the Debye temperature, $T < \Theta_D/50$. By introducing a cutoff energy in the two-level tunneling density of states, we can describe the excess specific heat observed in solid hcp $^4$He, as well as the low-temperature linear term in the specific heat. Agreement is found with recent measurements of the temperature behavior of both specific heat and pressure. These results suggest the presence of a very small fraction, at the parts-per-million (ppm) level, of two-level tunneling systems in solid $^4$He, irrespective of the existence of supersolidity.Comment: 11 pages, 4 figure

Defects and glassy dynamics in solid He-4: Perspectives and current status

We review the anomalous behavior of solid He-4 at low temperatures with particular attention to the role of structural defects present in solid. The discussion centers around the possible role of two level systems and structural glassy components for inducing the observed anomalies. We propose that the origin of glassy behavior is due to the dynamics of defects like dislocations formed in He-4. Within the developed framework of glassy components in a solid, we give a summary of the results and predictions for the effects that cover the mechanical, thermodynamic, viscoelastic, and electro-elastic contributions of the glassy response of solid He-4. Our proposed glass model for solid He-4 has several implications: (1) The anomalous properties of He-4 can be accounted for by allowing defects to freeze out at lowest temperatures. The dynamics of solid He-4 is governed by glasslike (glassy) relaxation processes and the distribution of relaxation times varies significantly between different torsional oscillator, shear modulus, and dielectric function experiments. (2) Any defect freeze-out will be accompanied by thermodynamic signatures consistent with entropy contributions from defects. It follows that such entropy contribution is much smaller than the required superfluid fraction, yet it is sufficient to account for excess entropy at lowest temperatures. (3) We predict a Cole-Cole type relation between the real and imaginary part of the response functions for rotational and planar shear that is occurring due to the dynamics of defects. Similar results apply for other response functions. (4) Using the framework of glassy dynamics, we predict low-frequency yet to be measured electro-elastic features in defect rich He-4 crystals. These predictions allow one to directly test the ideas and very presence of glassy contributions in He-4.Comment: 33 pages, 13 figure

Electronic Health Record Functionality Needed to Better Support Primary Care

Electronic health records (EHRs) must support primary care clinicians and patients, yet many clinicians remain dissatisfied with their system. This manuscript presents a consensus statement about gaps in current EHR functionality and needed enhancements to support primary care. The Institute of Medicine primary care attributes were used to define needs and Meaningful Use (MU) objectives to define EHR functionality. Current objectives remain disease- rather than whole-person focused, ignoring factors like personal risks, behaviors, family structure, and occupational and environmental influences. Primary care needs EHRs to move beyond documentation to interpreting and tracking information over time as well as patient partnering activities, support for team based care, population management tools that deliver care, and reduced documentation burden. While Stage 3 MU’s focus on outcomes is laudable, enhanced functionality is still needed including EHR modifications, expanded use of patient portals, seamless integration with external applications, and advancement of national infrastructure and policies

Tunnelling defect nanoclusters in hcp 4He crystals: alternative to supersolidity

A simple model based on the concept of resonant tunnelling clusters of lattice defects is used to explain the low temperature anomalies of hcp 4He crystals (mass decoupling from a torsional oscillator, shear modulus anomaly, dissipation peaks, heat capacity peak). Mass decoupling is a result of an internal Josephson effect: mass supercurrent inside phase coherent tunnelling clusters. Quantitative results are in reasonable agreement with experiments.Comment: 13 pages, 5 figure