Fault and Equity: Implied Indemnity After \u3cem\u3eHoudaille\u3c/em\u3e

This article examines the doctrine of implied indemnity in light of the recent decision of the Supreme Court of Florida in Houdaille Industries, Inc. v. Edwards. The authors discuss the meaning of fault and no fault in terms of the mechanisms of accident law, develop three models for allocating accident losses, and evaluate the change in accident law introduced in Houdaille, concluding that the court achieved conceptual consistency at the expense of equity

Plasma protein binding of prednisolone in normal volunteers and arthritic patients

The plasma binding of prednisolone was studied in twenty normal volunteers and twenty rheumatoid arthritis patients. An in vitro assessment of the binding following the addition of prednisolone, prednisone, and hydrocortisone to the plasmas obtained from the subjects showed significant differences in the percentage of prednisolone bound. However, the differences observed were regarded as clinically insignificant. The plasma protein binding was determined by an in vitro equilibrium dialysis of the individual plasma samples at 37° C. Prednisolone levels on both sides of the dialysis membrane were determined using radioactivity and HPLC analytical methodologies. The percentages of prednisolone bound calculated from the analytical results of either the radiochemical or HPLC method were not significantly different. The change in the percentage of prednisolone bound to plasma proteins was studied as a function of the total prednisolone plasma concentration in a normal volunteer and in a systemic lupus erythematosis patient. As a result of prednisolone binding to both transcortin and albumin, the binding of prednisolone changes as a function of prednisolone concentration. The binding data were fitted using nonlinear least squares regression, and the affinity constants for the binding of prednisolone to transcortin and albumin were estimated.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/46638/1/228_2004_Article_BF00568200.pd

Antithesis to hermetic architecture

Thesis: M. Arch., Massachusetts Institute of Technology, Department of Architecture, 2018.This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.Cataloged from student-submitted PDF version of thesis.Includes bibliographical references (pages 142-143).This exploration is framed around 3 near-future scenarios where the world has been transformed by environmental disasters. Basically our immunological bubble has been broken. For years, we have tried to control our environment by creating a separate homeostatic interior. And In the process of trying to achieve physical comfort, not only have we standardized our sensorial conditions into a homogenous experience, we have also destroyed the larger environment. While most of us knew that this bubble was going to burst at some point, none of us were prepared... Now in the post bubble world, we have slowly come to the realization that the answer is not to create bigger or better bubbles. Instead, we need to develop a second skin. Operating at the body scale, this series of prosthetics teaches us how to reintegrate our senses with the environment. They restore our natural ability to interact with air, water, and heat in a world post hermetic seals. Rather than simply protecting us in another mini bubble, they function as a layer of mediation between us and our environment.by Sophia W. Chesrow.M. Arch