1,326 research outputs found

    Purchase or rent? Optimal pricing for 3D printing capacity sharing platforms

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    Online sharing platforms have attracted considerable research and management attention across a number of industries, including travel, real estate, and cloud computing. They also have great potential for the 3D printing (3DP) industry, offering users the choice between owning or renting 3DP capacity. For matching supply and demand, capacity pricing is crucial. In this paper we consider two fundamental questions concerning pricing: (i) What is the optimal pricing strategy for a 3DP capacity sharing platform? (ii) How do usage level and printer heterogeneity affect consumers’ choice between in-house printing (owning) and outsourcing (renting)? Using queuing analysis, we derive the structural properties of the solutions to the problems. Furthermore, we conduct numerical studies using real-world data to generate managerial insights from the analytical findings. A key finding is that governments should focus on encouraging technological progress to lower the printers’ prices in order to improve the well-being of the industry. When considering two types of printers, we find that it is more beneficial for the platform if the high capacity printer dominates the market, as the platform then retains the prominent role in “redistributing” the 3DP capacity.</p

    Redox-Linked Domain Movements in the Catalytic Cycle of Cytochrome P450 Reductase

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    SummaryNADPH-cytochrome P450 reductase is a key component of the P450 mono-oxygenase drug-metabolizing system. There is evidence for a conformational equilibrium involving large-scale domain motions in this enzyme. We now show, using small-angle X-ray scattering (SAXS) and small-angle neutron scattering, that delivery of two electrons to cytochrome P450 reductase leads to a shift in this equilibrium from a compact form, similar to the crystal structure, toward an extended form, while coenzyme binding favors the compact form. We present a model for the extended form of the enzyme based on nuclear magnetic resonance and SAXS data. Using the effects of changes in solution conditions and of site-directed mutagenesis, we demonstrate that the conversion to the extended form leads to an enhanced ability to transfer electrons to cytochrome c. This structural evidence shows that domain motion is linked closely to the individual steps of the catalytic cycle of cytochrome P450 reductase, and we propose a mechanism for this

    R-parity-violating SUSY and CP violation in B --> phi K_s

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    Recent measurements of CP asymmetry in B --> phi K_S appear to be inconsistent with Standard Model expectations. We explore the effect of R-parity-violating SUSY to understand the data.Comment: Equations corrected. Conclusions unchanged. Latex, 6 pages, one fi

    White Light Interferometry for Quantitative Surface Characterization in Ion Sputtering Experiments

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    White light interferometry (WLI) can be used to obtain surface morphology information on dimensional scale of millimeters with lateral resolution as good as ~1 {\mu}m and depth resolution down to 1 nm. By performing true three-dimensional imaging of sample surfaces, the WLI technique enables accurate quantitative characterization of the geometry of surface features and compares favorably to scanning electron and atomic force microscopies by avoiding some of their drawbacks. In this paper, results of using the WLI imaging technique to characterize the products of ion sputtering experiments are reported. With a few figures, several example applications of the WLI method are illustrated when used for (i) sputtering yield measurements and time-to-depth conversion, (ii) optimizing ion beam current density profiles, the shapes of sputtered craters, and multiple ion beam superposition and (iii) quantitative characterization of surfaces processed with ions. In particular, for sputter depth profiling experiments of 25Mg, 44Ca and 53Cr ion implants in Si (implantation energy of 1 keV per nucleon), the depth calibration of the measured depth profile curves determined by the WLI method appeared to be self-consistent with TRIM simulations for such projectile-matrix systems. In addition, high depth resolution of the WLI method is demonstrated for a case of a Genesis solar wind Si collector surface processed by gas cluster ion beam: a 12.5 nm layer was removed from the processed surface, while the transition length between the processed and untreated areas was 150 {\mu}m.Comment: Applied Surface Science, accepted: 7 pages and 8 figure

    Threshold criterion for wetting at the triple point

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    Grand canonical simulations are used to calculate adsorption isotherms of various classical gases on alkali metal and Mg surfaces. Ab initio adsorption potentials and Lennard-Jones gas-gas interactions are used. Depending on the system, the resulting behavior can be nonwetting for all temperatures studied, complete wetting, or (in the intermediate case) exhibit a wetting transition. An unusual variety of wetting transitions at the triple point is found in the case of a specific adsorption potential of intermediate strength. The general threshold for wetting near the triple point is found to be close to that predicted with a heuristic model of Cheng et al. This same conclusion was drawn in a recent experimental and simulation study of Ar on CO_2 by Mistura et al. These results imply that a dimensionless wetting parameter w is useful for predicting whether wetting behavior is present at and above the triple temperature. The nonwetting/wetting crossover value found here is w circa 3.3.Comment: 15 pages, 8 figure

    New-Physics Effects on Triple-Product Correlations in Lambda_b Decays

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    We adopt an effective-lagrangian approach to compute the new-physics contributions to T-violating triple-product correlations in charmless Lambda_b decays. We use factorization and work to leading order in the heavy-quark expansion. We find that the standard-model (SM) predictions for such correlations can be significantly modified. For example, triple products which are expected to vanish in the SM can be enormous (~50%) in the presence of new physics. By measuring triple products in a variety of Lambda_b decays, one can diagnose which new-physics operators are or are not present. Our general results can be applied to any specific model of new physics by simply calculating which operators appear in that model.Comment: 20 pages, LaTeX, no figures. Added a paragraph (+ references) discussing nonfactorizable effects. Conclusions unchange

    Periodic solutions for a class of nonlinear partial differential equations in higher dimension

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    We prove the existence of periodic solutions in a class of nonlinear partial differential equations, including the nonlinear Schroedinger equation, the nonlinear wave equation, and the nonlinear beam equation, in higher dimension. Our result covers cases where the bifurcation equation is infinite-dimensional, such as the nonlinear Schroedinger equation with zero mass, for which solutions which at leading order are wave packets are shown to exist.Comment: 34 page

    Instability of vortex array and transitions to turbulent states in rotating helium II

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    We consider superfluid helium inside a container which rotates at constant angular velocity and investigate numerically the stability of the array of quantized vortices in the presence of an imposed axial counterflow. This problem was studied experimentally by Swanson {\it et al.}, who reported evidence of instabilities at increasing axial flow but were not able to explain their nature. We find that Kelvin waves on individual vortices become unstable and grow in amplitude, until the amplitude of the waves becomes large enough that vortex reconnections take place and the vortex array is destabilized. The eventual nonlinear saturation of the instability consists of a turbulent tangle of quantized vortices which is strongly polarized. The computed results compare well with the experiments. Finally we suggest a theoretical explanation for the second instability which was observed at higher values of the axial flow

    Ellipse-based Principal Component Analysis for Self-intersecting Curve Reconstruction from Noisy Point Sets

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    Surface reconstruction from cross cuts usually requires curve reconstruction from planar noisy point samples -- The output curves must form a possibly disconnected 1manifold for the surface reconstruction to proceed -- This article describes an implemented algorithm for the reconstruction of planar curves (1manifolds) out of noisy point samples of a sel-fintersecting or nearly sel-fintersecting planar curve C -- C:[a,b]⊂R→R is self-intersecting if C(u)=C(v), u≠v, u,v∈(a,b) (C(u) is the self-intersection point) -- We consider only transversal self-intersections, i.e. those for which the tangents of the intersecting branches at the intersection point do not coincide (C′(u)≠C′(v)) -- In the presence of noise, curves which self-intersect cannot be distinguished from curves which nearly sel fintersect -- Existing algorithms for curve reconstruction out of either noisy point samples or pixel data, do not produce a (possibly disconnected) Piecewise Linear 1manifold approaching the whole point sample -- The algorithm implemented in this work uses Principal Component Analysis (PCA) with elliptic support regions near the selfintersections -- The algorithm was successful in recovering contours out of noisy slice samples of a surface, for the Hand, Pelvis and Skull data sets -- As a test for the correctness of the obtained curves in the slice levels, they were input into an algorithm of surface reconstruction, leading to a reconstructed surface which reproduces the topological and geometrical properties of the original object -- The algorithm robustly reacts not only to statistical noncorrelation at the self-intersections(nonmanifold neighborhoods) but also to occasional high noise at the nonselfintersecting (1manifold) neighborhood

    Soil biochemistry and microbial activity in vineyards under conventional and organic management at Northeast Brazil.

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    The São Francisco Submedium Valley is located at the Brazilian semiarid region and is an important center for irrigated fruit growing. This region is responsible for 97% of the national exportation of table grapes, including seedless grapes. Based on the fact that orgThe São Francisco Submedium Valley is located at the Brazilian semiarid region and is an important center for irrigated fruit growing. This region is responsible for 97% of the national exportation of table grapes, including seedless grapes. Based on the fact that organic fertilization can improve soil quality, we compared the effects of conventional and organic soil management on microbial activity and mycorrhization of seedless grape crops. We measured glomerospores number, most probable number (MPN) of propagules, richness of arbuscular mycorrhizal fungi (AMF) species, AMF root colonization, EE-BRSP production, carbon microbial biomass (C-MB), microbial respiration, fluorescein diacetate hydrolytic activity (FDA) and metabolic coefficient (qCO2). The organic management led to an increase in all variables with the exception of EE-BRSP and qCO2. Mycorrhizal colonization increased from 4.7% in conventional crops to 15.9% in organic crops. Spore number ranged from 4.1 to 12.4 per 50 g-1 soil in both management systems. The most probable number of AMF propagules increased from 79 cm-3 soil in the conventional system to 110 cm-3 soil in the organic system. Microbial carbon, CO2 emission, and FDA activity were increased by 100 to 200% in the organic crop. Thirteen species of AMF were identified, the majority in the organic cultivation system. Acaulospora excavata, Entrophospora infrequens, Glomus sp.3 and Scutellospora sp. were found only in the organically managed crop. S. gregaria was found only in the conventional crop. Organically managed vineyards increased mycorrhization and general soil microbial activity
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