2,200 research outputs found
Experimental Test of Tracking the King Problem
In quantum theory, the retrodiction problem is not as clear as its classical
counterpart because of the uncertainty principle of quantum mechanics. In
classical physics, the measurement outcomes of the present state can be used
directly for predicting the future events and inferring the past events which
is known as retrodiction. However, as a probabilistic theory,
quantum-mechanical retrodiction is a nontrivial problem that has been
investigated for a long time, of which the Mean King Problem is one of the most
extensively studied issues. Here, we present the first experimental test of a
variant of the Mean King Problem, which has a more stringent regulation and is
termed "Tracking the King". We demonstrate that Alice, by harnessing the shared
entanglement and controlled-not gate, can successfully retrodict the choice of
King's measurement without knowing any measurement outcome. Our results also
provide a counterintuitive quantum communication to deliver information hidden
in the choice of measurement.Comment: 16 pages, 5 figures, 2 table
A Primary Study of Heavy Baryons Lambda_Q, Xi_Q, Sigma_Q and Omega_Q
We perform a preliminary study of the 1/2+ and 3/2+ ground-state baryons
containing a heavy quark in the framework of the chiral SU(3) quark model. By
using the calculus of variations, masses of Lambda_Q, Sigma_Q, Xi_Q, Omega_Q,
Sigma_Q^*, Xi_Q^* and Omega_Q^*, where Q means c or b quark, are calculated.
With taking reasonable model parameters, the numerical results of established
heavy baryons are generally in agreement with the available experimental data,
except that those of Xi_Q are somewhat heavier. For Omega_b with undetermined
experimental mass and nobserved Xi_b^*, Omega_b^*, reasonable theoretical
predictions are obtained. Interactions inside baryons are also discussed.Comment: 5 page
Down-regulation of Toll-like receptor 4 gene expression by short interfering RNA attenuates bone cancer pain in a rat model
<p>Abstract</p> <p>Background</p> <p>This study demonstrates a critical role in CNS innate immunity of the microglial Toll-like receptor 4 (TLR4) in the induction and maintenance of behavioral hypersensitivity in a rat model of bone cancer pain with the technique of RNA interference (RNAi). We hypothesized that after intramedullary injection of Walker 256 cells (a breast cancer cell line) into the tibia, CNS neuroimmune activation and subsequent cytokine expression are triggered by the stimulation of microglial membrane-bound TLR4.</p> <p>Results</p> <p>We assessed tactile allodynia and spontaneous pain in female Sprague-Dawley (SD) rats after intramedullary injection of Walker 256 cells into the tibia. In a complementary study, TLR4 small interfering RNA(siRNA) was administered intrathecally to bone cancer pain rats to reduce the expression of spinal TLR4. The bone cancer pain rats treated with TLR4 siRNA displayed significantly attenuated behavioral hypersensitivity and decreased expression of spinal microglial markers and proinflammatory cytokines compared with controls. Only intrathecal injection of TRL4 siRNA at post-inoculation day 4 could prevent initial development of bone cancer pain; intrathecal injection of TRL4 siRNA at post-inoculation day 9 could attenuate, but not completely block, well-established bone cancer pain.</p> <p>Conclusions</p> <p>TLR4 might be the main mediator in the induction of bone cancer pain. Further study of this early, specific, and innate CNS/microglial response, and how it leads to sustained glial/neuronal hypersensitivity, might lead to new therapies for the prevention and treatment of bone cancer pain syndromes.</p
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