2,872 research outputs found

    Giant Magnons and Spiky Strings on S^3 with B-field

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    We study solutions for a rotating string on S^3 with a background NS-NS B-field and show the existence of spiky string and giant magnon as two limiting solutions. We make a connection to the sine-Gordon model via the Polyakov worldsheet action and study the effect of B-field. In particular, we find the magnon solution can be mapped to the excitation of a fractional spin chain. We conjecture a B-deformed SYM to be the gauge theory dual to this background.Comment: 22 pages, 3 figures, more references adde

    Centella asiatica extract protects against amyloid β1–40-induced neurotoxicity in neuronal cells by activating the antioxidative defence system

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    AbstractCentella asiatica (雷公根 léi gōng gēn) is a traditional medicinal herb with high antioxidant activity, which decreases amyloid-β (Aβ) deposition in the brain. At the same time, aggregated Aβ-induced oxidative stress is the trigger in the pathogenesis of Alzheimer's disease (AD). Here, we investigated the ability of C. asiatica ethanol extract (CAE) to protect PC12 and IMR32 cells from Aβ1–40-induced production of reactive oxygen species (ROS) and concomitant neurotoxicity. Aggregated Aβ1–40 treatment resulted in reduced cell viability, which can be reversed by cotreatment with 25, 50, and 100 μg/mL CAE. Moreover, CAE eliminated the Aβ1–40-mediated increase in ROS production. Thus, CAE-mediated protection against aggregated Aβ1–40-induced neurotoxicity is attributable to modulation of the antioxidative defense system in cells, including the activities of superoxide dismutase, catalase, glutathione peroxidase, glutathione reductase, and levels of glutathione and glutathione disulfide by CAE. This emphasizes the potential therapeutic and preventive value of CAE in the treatment of AD

    CALIBRATION OF PRESSURE SENSORS FOR HAND GRIP MEASUREMENT

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    The purpose of this study was to assess the accuracy of grip force sensors. Methods: Several standard weights were used to calibrate the grip sensor in the static condition, The descriptive statistics and linear regression were used to present the accuracy and errors. Results: Results of this study showed a high level of sensing areas linear relationship under static loading. Conclusion: Data from this study showed high accuracy of the pressure sensor. The pressure sensor could te used for hand grip measurement
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