The boundary of holistic processing in the appraisal of facial attractiveness

© 2018 The Authors. Facial attractiveness is often studied on the basis of the internal facial features alone. This study investigated how this exclusion of the external features affects the perception of attractiveness. We studied the effects of two most commonly used methods of exclusion, where the shape of an occluding mask was defined by either the facial outline or an oval. Participants rated attractiveness of the same faces under these conditions. Results showed that faces were consistently rated more attractive when they were masked by an oval shape rather than by their outline (Experiment 1). Attractive faces were more strongly affected by this effect than were less attractive faces when participants were able to control the viewing time. However, unattractive faces benefited more from this effect when the same face stimuli were presented briefly for only 20 ms (Experiment 2). Further manipulation confirmed that the effect was mainly due to the occlusion of a larger area of the external features rather than the regular and symmetrical features of the oval shape (Experiment 3) or lacks contextual cues about the face boundary (Experiment 4). The effect was only relative to masked faces, with no advantage over unmasked faces (Experiment 5), and is likely a result of the interaction between the shape of a mask and the internal features of the face. This holistic effect in the appraisal of facial attractiveness is striking, because the oval shape of the mask is not a part of the face but is the edge of an occluding object

A Direct Approach to Simultaneous Tests of Superiority and Noninferiority with Multiple Endpoints

Simultaneous tests of superiority and non-inferiority hypotheses on multiple endpoints are often performed in clinical trials to demonstrate that a new treatment is superior over a control on at least one endpoint and non-inferior on the remaining endpoints. Existing methods tackle this problem by testing the superiority and non-inferiority hypotheses separately and control the Type I error rate each at $\alpha$ level. In this paper we propose a unified approach to testing the superiority and non-inferiority hypotheses simultaneously. The proposed approach is based on the UI-IU test and the least favorable configurations of the combined superiority and non-inferiority hypotheses, which leads to the solution of an adjusted significance level $\alpha'$ for marginal tests that controls the overall Type I error rate at pre-defined $\alpha$. Simulations show that the proposed approach maintains a higher power than existing methods in the settings under investigation. Since the adjusted significance level $\alpha'$ is obtained by controlling the Type I error rate at $\alpha$, one can easily construct the exact $(1 - \alpha)\%$ simultaneous confidence intervals for treatment effects on all endpoints. The proposed approach is illustrated with two real examples

Revealing spatio-spectral electroencephalographic dynamics of musical mode and tempo perception by independent component analysis.

BackgroundMusic conveys emotion by manipulating musical structures, particularly musical mode- and tempo-impact. The neural correlates of musical mode and tempo perception revealed by electroencephalography (EEG) have not been adequately addressed in the literature.MethodThis study used independent component analysis (ICA) to systematically assess spatio-spectral EEG dynamics associated with the changes of musical mode and tempo.ResultsEmpirical results showed that music with major mode augmented delta-band activity over the right sensorimotor cortex, suppressed theta activity over the superior parietal cortex, and moderately suppressed beta activity over the medial frontal cortex, compared to minor-mode music, whereas fast-tempo music engaged significant alpha suppression over the right sensorimotor cortex.ConclusionThe resultant EEG brain sources were comparable with previous studies obtained by other neuroimaging modalities, such as functional magnetic resonance imaging (fMRI) and positron emission tomography (PET). In conjunction with advanced dry and mobile EEG technology, the EEG results might facilitate the translation from laboratory-oriented research to real-life applications for music therapy, training and entertainment in naturalistic environments

Asymmetry of Left Versus Right Lateral Face in Face Recognition

Prior research has found that the left side of the face is emotionally more expressive than the right side [1]. This was demonstrated in a study where the right and the left halves of a face image were combined with their mirror-reversed duplicates to make composite images. When observers were asked which composite face appeared more emotional, they selected the left-left over the right-right composite more often

Exosomes From miRNA-126-Modified Endothelial Progenitor Cells Alleviate Brain Injury and Promote Functional Recovery After Stroke

Aims: We previously showed that the protective effects of endothelial progenitor cells (EPCs)-released exosomes (EPC-EXs) on endothelium in diabetes. However, whether EPC-EXs are protective in diabetic ischemic stroke is unknown. Here, we investigated the effects of EPC-EXs on diabetic stroke mice and tested whether miR-126 enriched EPC-EXs (EPC-EXs miR126 ) have enhanced efficacy. Methods: The db/db mice subjected to ischemic stroke were intravenously administrated with EPC-EXs 2 hours after ischemic stroke. The infarct volume, cerebral microvascular density (MVD), cerebral blood flow (CBF), neurological function, angiogenesis and neurogenesis, and levels of cleaved caspase-3, miR-126, and VEGFR2 were measured on day 2 and 14. Results: We found that (a) injected EPC-EXs merged with brain endothelial cells, neurons, astrocytes, and microglia in the peri-infarct area; (b) EPC-EXs miR126 were more effective than EPC-EXs in decreasing infarct size and increasing CBF and MVD, and in promoting angiogenesis and neurogenesis as well as neurological functional recovery; (c) These effects were accompanied with downregulated cleaved caspase-3 on day 2 and vascular endothelial growth factor receptor 2 (VEGFR2) upregulation till day 14. Conclusion: Our results indicate that enrichment of miR126 enhanced the therapeutic efficacy of EPC-EXs on diabetic ischemic stroke by attenuating acute injury and promoting neurological function recovery

Prompting Large Language Models to Reformulate Queries for Moment Localization

The task of moment localization is to localize a temporal moment in an untrimmed video for a given natural language query. Since untrimmed video contains highly redundant contents, the quality of the query is crucial for accurately localizing moments, i.e., the query should provide precise information about the target moment so that the localization model can understand what to look for in the videos. However, the natural language queries in current datasets may not be easy to understand for existing models. For example, the Ego4D dataset uses question sentences as the query to describe relatively complex moments. While being natural and straightforward for humans, understanding such question sentences are challenging for mainstream moment localization models like 2D-TAN. Inspired by the recent success of large language models, especially their ability of understanding and generating complex natural language contents, in this extended abstract, we make early attempts at reformulating the moment queries into a set of instructions using large language models and making them more friendly to the localization models.Comment: 4 pages, 2 figure

Comprehensive estimation of lake volume changes on the Tibetan Plateau during 1976–2019 and basin-wide glacier contribution

This study was supported by grants from the Natural Science Foundation of China (41831177 , 41871056), the European Space Agency within the Dragon 4 program ( 4000121469/17/I-NB), the Swiss National Science Foundation (No. 200021E_177652/1) within the framework of the DFG Research Unit GlobalCDA (FOR2630), and the French Space Agency (CNES ). G. Zhang wants to thank the China Scholarship Council for supporting his visit to University of Zurich (the former affiliation of T. Bolch) from December 2017 to December 2018.Volume changes and water balances of the lakes on the Tibetan Plateau (TP) are spatially heterogeneous and the lake-basin scale drivers remain unclear. In this study, we comprehensively estimated water volume changes for 1132 lakes larger than 1 km2 and determined the glacier contribution to lake volume change at basin-wide scale using satellite stereo and multispectral images. Overall, the water mass stored in the lakes increased by 169.7 ± 15.1 Gt (3.9 ± 0.4 Gt yr−1) between 1976 and 2019, mainly in the Inner-TP (157.6 ± 11.6 or 3.7 ± 0.3 Gt yr−1). A substantial increase in mass occurred between 1995 and 2019 (214.9 ± 12.7 Gt or 9.0 ± 0.5 Gt yr−1), following a period of decrease (−45.2 ± 8.2 Gt or −2.4 ± 0.4 Gt yr−1) prior to 1995. A slowdown in the rate of water mass increase occurred between 2010 and 2015 (23.1 ± 6.5 Gt or 4.6 ± 1.3 Gt yr−1), followed again by a high value between 2015 and 2019 (65.7 ± 6.7 Gt or 16.4 ± 1.7 Gt yr−1). The increased lake-water mass occurred predominately in glacier-fed lakes (127.1 ± 14.3 Gt) in contrast to non-glacier-fed lakes (42.6 ± 4.9 Gt), and in endorheic lakes (161.9 ± 14.0 Gt) against exorheic lakes (7.8 ± 5.8 Gt) over 1976–2019. Endorheic and glacier-fed lakes showed strongly contrasting patterns with a remarkable storage increase in the northern TP and slight decrease in the southern TP. The ratio of excess glacier meltwater runoff to lake volume increase between 2000 and ~2019 was less than 30% for the entire Inner-TP based on several independent data sets. Among individual lake-basins, 14 showed a glacier contribution to lake volume increase of 0.3% to 29.1%. The other eight basins exhibited a greater glacier contribution of 116% to 436%, which could be explained by decreased net precipitation. The lake volume change and basin scale glacier contribution reveal that the enhanced precipitation predominantly drives lake volume increase but it is spatially heterogeneous.PostprintPeer reviewe