Strategies for High-Throughput, Templated Zeolite Synthesis

How best to design and redesign high-throughput experiments for zeolite synthesis is addressed. A model that relates materials function to chemical composition of the zeolite and the structure directing agent is introduced. Using this model, several Monte Carlo-like design protocols are evaluated. Multi-round protocols are found to be effective, and strategies that use a priori information about the structure-directing libraries are found to be the best.Comment: 21 pages. 3 figure

BAG : Managing GPU as buffer cache in operating systems

This paper presents the design, implementation and evaluation of BAG, a system that manages GPU as the buffer cache in operating systems. Unlike previous uses of GPUs, which have focused on the computational capabilities of GPUs, BAG is designed to explore a new dimension in managing GPUs in heterogeneous systems where the GPU memory is an exploitable but always ignored resource. With the carefully designed data structures and algorithms, such as concurrent hashtable, log-structured data store for the management of GPU memory, and highly-parallel GPU kernels for garbage collection, BAG achieves good performance under various workloads. In addition, leveraging the existing abstraction of the operating system not only makes the implementation of BAG non-intrusive, but also facilitates the system deployment

Equation-free Dynamic Renormalization of a KPZ-type Equation

In the context of equation-free computation, we devise and implement a procedure for using short-time direct simulations of a KPZ type equation to calculate the self-similar solution for its ensemble averaged correlation function. The method involves "lifting" from candidate pair-correlation functions to consistent realization ensembles, short bursts of KPZ-type evolution, and appropriate rescaling of the resulting averaged pair correlation functions. Both the self-similar shapes and their similarity exponents are obtained at a computational cost significantly reduced to that required to reach saturation in such systems

BAG: Managing GPU as Buffer Cache in Operating Systems

This paper presents the design, implementation and evaluation of BAG, a system that manages GPU as the buffer cache in operating systems. Unlike previous uses of GPUs, which have focused on the computational capabilities of GPUs, BAG is designed to explore a new dimension in managing GPUs in heterogeneous systems where the GPU memory is an exploitable but always ignored resource. With the carefully designed data structures and algorithms, such as concurrent hashtable, log-structured data store for the management of GPU memory, and highly-parallel GPU kernels for garbage collection, BAG achieves good performance under various workloads. In addition, leveraging the existing abstraction of the operating system not only makes the implementation of BAG non-intrusive, but also facilitates the system deployment

Plasma NT pro-BNP, hs-CRP and big-ET levels at admission as prognostic markers of survival in hospitalized patients with dilated cardiomyopathy: a single-center cohort study

BACKGROUND: Circulating N-terminal pro-B-type natriuretic peptide (NT pro-BNP), high- sensitivity C-reactive protein (hs-CRP) and big endothelin (big-ET) have been shown to be increased in heart failure and to contribute to both hemodynamic deterioration and cardiovascular remodeling. Here, we examined the prognostic value of the three neurohormones at admission in a population of hospitalized patients with dilated cardiomyopathy (DCM). METHODS AND RESULTS: This cohort study was undertaken in 622 hospitalized patients with DCM in Fuwai Hospital from January 2005 to September 2011 (female 26.5%, 51.4 ± 14.6 years old). Standard demographics, echocardiography and routine blood samples were obtained shortly after admission. NT pro-BNP, hs-CRP and big-ET were measured, and their concentrations in relation to all-cause mortality were assessed through a mean follow-up of 2.6 ± 1.6 years. Kaplan-Meier curves showed that the all-cause mortality rates were higher in patients with NT pro-BNP > 2247 pmol/L compared to patients with NT pro-BNP < 2247 pmol/L (11.9% vs 34.8%, log-rank χ(2) = 35.588, P < 0.001), in patients with hs-CRP > 3.90 mg/L compared to patients with hs-CRP < 3.90 mg/L (12.8% vs 33.6%, log-rank χ(2) = 39.662, P < 0.001) and in patients with big-ET > 0.95 pmol/L compared to patients with big-ET <0.95 pmol/L (12.5% vs 31.0%, log-rank χ(2) = 17.890, P < 0.001). High circulating concentrations of NT pro-BNP (HR 2.217, 95% CI 1.015-4.846, P = 0.046) and hs-CRP (HR 1.922, 95% CI 1.236-2.988, P = 0.004), but not big-ET, in addition to left atrial diameter and fasting blood glucose, were independent predictors of the outcome defined as all-cause mortality. CONCLUSIONS: In a large population of patients with DCM, the circulating concentrations of NT pro-BNP and hs-CRP, but not big-ET, were independent markers of all-cause mortality