Time series study on the effect of low air pollution level NO2 On the death of residents from cardiovascular and cerebrovascular diseases

Objective: To explore the impact of low-level atmospheric nitrogen dioxide (NO2) on the death risk of cardiovascular and cerebrovascular diseases in Enshi City, so as to provide scientific basis for locating sensitive populations and formulating population health policiesmethods the monitoring of air pollutants, meteorological factors and death data of residents from cardiovascular and cerebrovascular diseases in Enshi City from 2015 to 2018 were collected. The generalized additive model based on Poisson distribution was used to analyze the impact of low air pollution level NO2 on the death risk of cardiovascular and cerebrovascular diseases in Enshi City, and subgroup analysis was carried out on age, gender and seasonresults the average concentrations of major gaseous pollutants in Enshi from 2015 to 2018 were NO2 (21.40 μg/m3), sulfur dioxide (so, 9.68 μg/m3). Carbon oxide (CO, 0.88 mg/m3) and ozone (O, 61.21 μg/m3). The results of single pollutant model analysis show that every increase of NO2 concentration in the total population μg/m, the risk of death from cardiovascular and cerebrovascular diseases on the same day (lag0) will increase by 0.33% (-0.06%~0.72%) (P>0.05); In the female population, every 1% increase in NO2 concentration μg/m, the death risk of cardiovascular and cerebrovascular diseases with cumulative lag of 1 day (lag01) will increase by 0.92% (0.26%~1.56%) (P < 0.05); In the cold season, every increase of NO2 concentration μg/m, the death risk of cardiovascular and cerebrovascular diseases in the whole population on the same day (lag0) will increase by 0.62% (0.12%~1.12%) (P < 0.05). The results of the two pollutant model show that after controlling other gaseous pollutants (SO2, Co or O3), the impact of NO2 on the death risk of cardiovascular and cerebrovascular diseases in women and the whole population in cold season still exists. Conclusion: Low pollution level of NO2 in Enshi City will increase the death risk of cardiovascular and cerebrovascular diseases among women and the whole population in cold season. Attention should be paid to the health protection of special populations in low pollution areas and in special seasons