Study of the frequency of female genital tract infection using cartridge based nucleic acid amplification test

Background: The aim of the study was to study the frequency of female genital tract infection using cartridge based nucleic acid amplification test (CBNAAT), to study the sensitivity, specificity, positive predictive value, negative predictive value and diagnostic accuracy of CBNAAT.Methods: This prospective observational study was conducted among 100 patients as per inclusion criteria with genital tract infection in Swami Vivekanand Subharti University, Meerut over a period of two years. Investigations including ZN staining for acid fast bacillus (AFB), endometrial sampling for histopathology, CBNAAT and BACTEC culture were sent.Results: In a study of 100 patients’ histopathological examination detected tuberculosis in 2% patients while CBNAAT detected tuberculosis in 5% patients. Tubercle bacilli was found in 3% women on AFB stain while in only 1%-woman genital tuberculosis was diagnosed by BACTEC culture.Conclusions: Female genital tuberculosis is detected most frequently when a woman presents with unexplained infertility. Newer technologies allow genital tuberculosis to be identified at an earlier stage and enable us to provide treatment. CBNAAT being a sensitive test picked up more cases than histopathology, culture, AFB stain. Hence CBNAAT should be widely used for early detection of female genital tuberculosis

A case report on serous cyst fibroadenoma of ovary

A 16-year-old unmarried female patient presented to the Subharti hospital with a lump in her abdomen that had been there for one year. For the previous two months, there had been abdominal pain. Constipation, intermittent fever, and vomiting were all present. A mass of around 25×25 cm (approximately) was found on per-abdominal examination, which was firm in consistency, non-tender, afebrile to touch with smooth borders, and restricted mobility. On the basis of the above mentioned examination and investigation, a diagnosis of ovarian cyst with typhoid immunoglobulin G (IgG) and immunoglobulin M (IgM) positive, dengue IgG with hepatitis B surface antigen (HbsAg) positive was made