Alternating Current All-electrical Gun Control System in Tanks

The ac all-electrical gun control system is composed of permanent magnetic synchronous machine-drive control systems and the ball-screw by replacing the complicated electrohydraulic systems. At the same time, the variable-structure system with sliding modes makes the gun control systems to have higher performances using the only rate flexure gyroscope. Thereby, vehicle hull gyroscope and angular gyroscope are left out.The new ac all-electrical gun control systems developed are reduced by 40 per cent in weight, decreased by 30 per cent in volume, increased by 35 per cent in efficiency, and enhanced by three times in service life as compared to the current gun control systems

Response of Fertile Tiller Characters and Seed Yield of \u3cem\u3eElymus sibiricus\u3c/em\u3e L. to Row Space Alteration

Elymus sibiricus L. cv chuancao NO.2 is widely planted in the eastern Tibetan Plateau of China. At present, the study about E. sibiricus L. seed yield has focused on the influence of fertilizing and harvest time on seed yield and its components. The response of fertile tiller characters and seed yield of E. sibiricus L. to different row space still has not been reported. This experiment analyzed the response of fertile tiller characters and seed yield to different row spaces, and presents the optimal spacing to increase seed yield and quality in the Northwest Plateau of Sichuan. The objective was to provide a scientific basis for large-scale seed production

Modeling and simulation of extended ant colony labor division for benefit distribution of the all-for-one tourism supply chain with front and back decoupling

This paper takes the supply chain alliance under the decoupling of the front and back of the all-for-one tourism as the research object. Considering the three behavior stimuli of self-benefit, altruism, and invariance, this article resets the attributes such as environmental stimuli and response threshold of ants based on the characteristics of the all-for-one tourism supply chain with shared services as the core under the decoupling of the front and back. Moreover, it introduces dual intervention factors to coordinate the benefit distribution process of different member companies, takes fairness as the main goal of benefit distribution, introduces relative deprivation as the measure index of fairness, and establishes a dynamic all-for-one tourism supply chain alliance benefit distribution model. The experimental results show that the extended model has good flexibility of benefit distribution and realizes the fair distribution of supply chain benefits

Drivers of population divergence and genetic variation in Elymus breviaristatus (Keng) Keng f. (Poaceae: Triticeae), an endemic perennial herb of the Qinghai-Tibet plateau

Elymus breviaristatus, a rare grass species with excellent resistance and ecological importance, is narrowly distributed on the Qinghai-Tibet plateau. Populations of E. breviaristatus are declining due to habitat fragmentation, and thus far, characteristics of genetic differentiation and adaptive responses to climate change remain poorly understood in this species. Here, we explored the genetic structure of 18 natural populations (269 individuals) in the transition zone between Tibet and the Hengduan Mountains using 15 expressed sequence tag (EST)-SSR primer pairs and identified possible barriers to gene flow that might have caused genetic discontinuities. Additional analyses were performed to identify the environmental factors affecting genetic diversity and to test whether the patterns of genetic variation among populations were more consistent with the isolation by distance (IBD) or isolation by environment (IBE) model. Multiple measures of genetic diversity revealed that intra-population genetic variation was low, while inter-population genetic variation was high. Clustering, structure, and principal coordinate analyses identified three genetic groups: (a) Eastern Qamdo, (b) Nagqu and Western Qamdo, and (c) Lhasa and Nyingchi. A clear physical barrier to gene flow was formed by the Yarlung Zangbo Grand Canyon and the Tanggula Mountains. We found that both IBD and IBE contributed to the observed patterns of genetic variation, and the IBE model played a leading role. In addition, precipitation-related variables, soil phosphorus content and soil K:P ratio significantly affected population genetic variation. Overall, our results emphasized the genetic fragility of E. breviaristatus populations and showed that this species requires attention, as future climate changes and human activities may further threaten its survival. In addition, the genetic differences among E. breviaristatus populations should be considered when formulating conservation measures for E. breviaristatus populations in the study area

Identification of ferroptosis-related genes in the progress of NASH

BackgroundNon-alcoholic steatohepatitis (NASH) is becoming more widespread, and some similarities exist between its etiology and ferroptosis. However, there are limited investigations on which ferroptosis-related genes (FRGs) are regulated in NASH and how to regulate them. We screened and validated the pivotal genes linked to ferroptosis in NASH to comprehend the function of ferroptosis in the development of NASH.MethodsTwo mRNA expression data were obtained from the Gene Expression Omnibus (GEO) as the training set and validation set respectively. FRGs were downloaded from FerrDb. The candidate genes were obtained from the intersection between differentially expressed genes (DEGs) and FRGs, and further analyzed using the Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG). The hub genes were identified by the protein-protein interaction (PPI) network and Cytoscape. Then, FRGs closely related to the severity of NASH were identified and further confirmed using the validation set and mouse models. Ultimately, based on these genes, a diagnostic model was established to differentiate NASH from normal tissues using another data set from GEO.ResultsA total of 327 FRGs in NASH were acquired and subjected to GSEA. And 42 candidate genes were attained by overlapping the 585 FRGs with 2823 DEGs, and enrichment analysis revealed that these genes were primarily engaged in the fatty acid metabolic, inflammatory response, and oxidative stress. A total of 10 hub genes (PTGS2、IL1B、IL6、NQO1、ZFP36、SIRT1、ATF3、CDKN1A、EGR1、NOX4) were then screened by PPI network. The association between the expression of 10 hub genes and the progress of NASH was subsequently evaluated by a training set and verified by a validation set and mouse models. CDKN1A was up-regulated along with the development of NASH while SIRT1 was negatively correlated with the course of the disease. And the diagnostic model based on CDKN1A and SIRT1 successfully distinguished NASH from normal samples.ConclusionIn summary, our findings provide a new approach for the diagnosis, prognosis, and treatment of NASH based on FRGs, while advancing our understanding of ferroptosis in NASH

Inflammatory Links Between High Fat Diets and Diseases

In recent years, chronic overnutrition, such as consumption of a high-fat diet (HFD), has been increasingly viewed as a significant modifiable risk factor for diseases such as diabetes and certain types of cancer. However, the mechanisms by which HFDs exert adverse effects on human health remains poorly understood. Here, this paper will review the recent scientific literature about HFD-induced inflammation and subsequent development of diseases and cancer, with an emphasis on mechanisms involved. Given the expanding global epidemic of excessive HFD intake, understanding the impacts of a HFD on these medical conditions, gaining great insights into possible underlying mechanisms, and developing effective therapeutic strategies are of great importance