(E)-1-(4-Methyl­phen­yl)-3-[(1-phenyl­ethyl­idene)amino]­thio­urea

In the title compound, C16H17N3S, the amino­thio­urea unit is nearly planar (r.m.s. deviation = 0.0425 Å), and is twisted with respect to the tolyl and phenyl rings by 57.84 (7) and 15.88 (14)°, respectively; the tolyl and phenyl rings are twisted by 65.64 (11)° to each other. Inter­molecular N—H⋯S and weak C—H⋯S hydrogen bonds are present in the crystal structure

Ethyl 6-(4-fluoro­phen­yl)-4-hy­droxy-2-oxo-4-trifluoro­meth­yl-1,3-diazinane-5-carboxyl­ate monohydrate

The asymmetric unit of the title compound, C14H14F4N2O4·H2O, contains two crystallographically independent organic mol­ecules and two water mol­ecules. The two 1,3-diazinane rings adopt a half-chair conformation and the dihedral angles between their mean planes and those of the benzene rings are 75.65 (4)° and 49.41 (3)° in the two mol­ecules. The crystal structure is stabilized by inter­molecular O—H⋯O and N—H⋯O hydrogen bonds

Reanalysis of the Gross-Llewellyn Smith sum rule up to O(αs4){\cal O}(\alpha_s^4)-order QCD corrections

In the paper, we reanalyze the properties of Gross-Llewellyn Smith (GLS) sum rule by using the $\mathcal{O}(\alpha_s^4)$-order QCD corrections with the help of principle of maximum conformality (PMC). By using the PMC single-scale approach, we obtain an accurate renormalization scale-and-scheme independent pQCD contribution for GLS sum rule, e.g. $S^{\rm GLS}(Q_0^2=3{\rm GeV}^2)|_{\rm PMC}=2.559^{+0.023}_{-0.024}$, where the error is squared average of those from $\Delta\alpha_s(M_Z)$, the predicted $\mathcal{O}(\alpha_s^5)$-order terms predicted by using the Pad\'{e} approximation approach. After applying the PMC, a more convergent pQCD series has been obtained, and the contributions from the unknown higher-order terms are highly suppressed. In combination with the nonperturbative high-twist contribution, our final prediction of GLS sum rule agrees well with the experimental data given by the CCFR collaboration.Comment: 6 pages, 5 figure

The Prevalence of and Factors Associated With Anxiety and Depression Among Working-Age Adults in Mainland China at the Early Remission Stage of the Coronavirus 2019 Pandemic

Background: The Coronavirus 2019 (COVID-19) outbreak has led to a considerable proportion of adverse psychological symptoms in different subpopulations. This study aimed to investigate the status of anxiety and depression and their associated factors in the adult, working-age population in Mainland China at the early remission stage of the COVID-19 pandemic. Methods: An online study was conducted among 1,863 participants in 29 provinces in Mainland China from March 23 to 31, 2020. Their mental health was evaluated by the generalized anxiety disorder scale (GAD-7) and the patient health questionnaire (PHQ-9). Descriptive analysis, Chi-square, and multiple logistic regressions were applied. Results: About 44.5% of the participants had anxiety, 49.2% had depression, and 37.9% showed a combination of depression and anxiety. Around 83.7% of the participants claimed that the pandemic had a negative impact on their medical needs, which was the primary predictor of mental health, the degree of impact being positively related to the prevalence of anxiety and depression. More chronic diseases, moderate to bad self-rated health, severe perceived infection risk, and younger age group were the common risk factors for anxiety and depression. Having no children, unemployment, and a college-level educational background were associated with higher anxiety prevalence, whereas unmarried participants were correlated with higher depression prevalence. Conclusion: The working-age population showed a relatively high risk of anxiety and depression in Mainland China at the early remission stage of the pandemic. To improve medical services capacity for routine and delayed medical service needs should be a part of policy-makers\u27 priority agenda during this period of crisis

Totally thoracoscopic closure of ventricular septal defect without a robotically assisted surgical system: A summary of 119 cases

ObjectivesTo summarize the clinical outcomes of totally thoracoscopic closure of a ventricular septal defect (VSD).MethodsTotally thoracoscopic VSD closure was performed in 119 patients (66 boys; mean age, 7.1 ± 3.6 years). An additional 35 patients undergoing open-chest VSD closure were selected as a control group. Using 3 port incisions in the right chest, pericardiotomy, bicaval occlusion, atriotomy, and VSD closure were performed by thoracoscopy without the aid of a robotically assisted surgical system.ResultsCardiopulmonary bypass and aortic crossclamp times were 42.2 ± 9.8 and 32.5 ± 7.3 minutes, respectively. There were no deaths but 1 patient required insertion of a permanent pacemaker as a result of postoperative atrioventricular conduction block. The length of stay in the intensive care unit (11.0 ± 2.6 vs 22.9 ± 4.9 hours, P < .01) or postoperative hospital stay (4.2 ± 1.1 vs 6.6 ± 2.1 days, P < .03) in the thoracoscopic group were shorter than in the control group. The percentage of patients who required postoperative opioid analgesics in the thoracoscopic group was lower than in the control group (31.9% vs 74.2%, P < .001). Rate of blood transfusion during the operation (17.6% vs 65.7%, P = .001) and the postoperative use of opioid analgesics (31.9% vs 74.3%, P = .003) in the thoracoscopic group was lower than in the control group. Transesophageal echocardiographic analysis 4.6 ± 2.3 months after the operation showed complete closure of the defect.ConclusionsTotally thoracoscopic closure of VSD through a 3-port entry was safe and effective

Properties of the dense cores and filamentary structures in the Vela C molecular cloud

The initial and boundary conditions of the Galactic star formation in molecular clouds are not well understood. In an effort to shed new light on this long-standing problem, we measured properties of dense cores and filamentary structures in the Vela C molecular cloud, observed with Herschel. We applied the getsf extraction method to separate the components of sources and filaments from each other and their backgrounds, before detecting, measuring, and cataloging the structures. The cores and filamentary structures constitute 40% of the total mass of Vela C, most of the material is in the low-density molecular background cloud. We selected 570 reliable cores, of which 149 are the protostellar cores and 421 are the starless cores. Almost 78% of the starless cores were identified with the gravitationally bound prestellar cores. The exponent of the CMF (alpha = 1.35) is identical to that of the Salpeter IMF. We selected 68 filaments with at least one side that appeared not blended with adjacent structures. The filament widths are in the range of 0.15 pc to 0.63 pc, and have a median value of W = 0.3(0.11) pc. The surface densities of filaments are well correlated with their contrasts and linear densities. Within uncertainties of the filament instability criterion, many filaments may well be both supercritical and subcritical. A large fraction of filaments may definitely be considered supercritical, in which are found 94 prestellar cores, 83 protostellar cores, and only 1 unbound starless core. Taking into account the uncertainties, the supercritical filaments contain only prestellar and protostellar cores. Our findings support the idea that there exists a direct relationship between the CMF and IMF and that filaments play a key role in the formation of prestellar cores, which is consistent with the previous Herschel results.Comment: 15 pages, 12 figures, 3 tables, accepted for publication in A&