A Case Report on Hepatozoon canis Infection in a Dog

A thin peripheral blood smear collected from a four years of old dog (Labrador breed) was received from the Referral Veterinary Clinical Complex, Indian Veterinary Research Institute, Izatnagar to the Division of Parasitology, Indian Veterinary Research Institute, Izatnagar for the diagnosis of haemoprotozoan disease during the month of October, 2023. Blood smear was screened for the parasitological examination using Giemsa’s stain showed positive for Hepatozoon canis. The dog was treated with single dose of Imidocarb dipropionate @ 6.6 mg/kg subcutaneously and Doxycycline @ 5mg/kg orally for 28 days with supportive therapy. The dog was infected with Hepatozoon canis conventionally diagnosed as well as therapeutically managed. Incidence of H. canis was documented in a dog from Bareilly district of Uttar Paradesh

Evan’s Syndrome Hemolytic Anemia with Thrombocytopenia in a Labrador Dog: A Case Report

A seven-year-old Labrador retriever intact male dog was presented to the Referral Veterinary Polyclinic, Indian Veterinary Research Institute, Izatanagar with a history of inappetance, melena, and petechial hemorrhages on the ventral abdomen and treated by a local veterinarian for a prolonged period of time. Clinical examination showed pale mucous membranes, peripheral lymphadenopathy, and mild hepatomegaly. A Complete blood count revealed anemia, leukopenia, and thrombocytopenia and serum biochemistry showed hypoalbuminemia and hypoproteinemia. The dog was suspected of having a haemoprotozoan infection, and a thin peripheral blood smear was submitted to the Division of Parasitology, Indian Veterinary Research Institute, Izatanagar, Bareilly, for examination. A blood smear was screened for haemoprotozoan examination using Giemsa’s stain, which showed positivity for Babesia vogeli. An abdominal ultrasound confirmed hepatic enlargement. The blood clotting profile reveals an increase in activated partial thromboplastin time and prothrombin time. The dog's blood sample tested negative for Babesia vogeli, B. gibsoni, E. canis, and H. canis by multiplex PCR; this could be because of prior initiation of antibiotics. A periheral blood smear showed elevated spherocytes count and saline agglutination test was positive. Based on history, clinical examinations, laboratory findings and cytological examinations the case was tentatively diagnosed as chronic case of tick fever with concomitant Evans syndrome. A blood transfusion was performed and around 300 ml of whole blood was infused. Treatment was initiated with triple antibiotic therapy and an immunosuppressive dose of steroids, but after 4 weeks, the dog succumbed to the condition. Further research is required to optimize treatment regimens for dogs with Evan's syndrome, as the prognosis is uncertain

Ehrlichia canis Infection in a Labrador Retriever Dog: A Case Report

A six-year-old Labrador retriever dog with a history of fever, inappetence, and unilateral epistaxis was presented to the Referral Veterinary Clinical Complex, Indian Veterinary Research Institute, Izatnagar. Clinical examination revealed the dog had pyrexia, an enlarged peripheral lymph node, and the presence of ticks on the body. The dog was suspected of having a haemoprotozoan infection, and a thin peripheral blood smear was submitted to the Division of Parasitology, Indian Veterinary Research Institute, Izatanagar, Bareilly, for examination. A blood smear was screened for haemoprotozoan examination using Giemsa’s stain, which showed positivity for Ehrlichia canis. Treatment was initiated with Doxycycline at 10 mg/kg B.wt. orally once for 28 days, along with supportive therapy, which resulted in a significant improvement in the dog's condition. An incidence of E. canis was reported from the Bareilly district of Uttar Pradesh