Immunopathology of Virus-Induced Anterior Uveitis

Herpes simplex virus, varicella zoster virus, human cytomegalovirus, and rubella virus are the most common causes of virus-induced anterior uveitis. They can present in a variety of entities not only with typical but also overlapping clinical ch

Structure determination of PF3 adsorption on Cu(100) using X-ray standing waves

The local structure of the Cu(100)c(4x2)-PF3 adsorption phase has been investigated through the use of normal-incidence X-ray standing waves (NIXSW), monitored by P 1s and F 1s photoemission, together with P K-edge near-edge X-ray absorption fine structure (NEXAFS). NEXAFS shows the molecule to be oriented with its C3v symmetry axis essentially perpendicular to the surface, while the P NIXSW data show the molecule to be adsorbed in atop sites 2.37±0.04 Å above the surface, this distance corresponding to the Cu-P nearest-neighbour distance in the absence of any surface relaxation. F NIXSW indicates a surprisingly small height difference of the P and F atoms above the surface 0.44±0.06 Å, compared with the value expected for an undistorted gas-phase geometry of 0.77 Å, implying significant increases in the F-P-F bond angles. In addition, however, the F NIXSW data indicate that the molecules have a well-defined azimuthal orientation with a molecular mirror plane aligned in a substrate mirror plane, and with a small (5-10°) tilt of the molecule in this plane such that the two symmetrically-equivalent F atoms in each molecule are tilted down towards the surface

Near-edge absorption fine structure and UV photoemission spectroscopy studies of aligned single-walled carbon nanotubes on Si(100) substrates

The self-assembled films of single-walled carbon nanotubes were studied. The study was carried out by using near-edge absorption fine structure (NEAFS) and UV photoemission spectroscopy (UPS). It was found that at lower angles of incidence, the intensity of π * core exciton at 284.4 eV, which attributed to the greater accessibility of the π * orbitals. The results from UPS spectra of the films showed little angular dependence and included features consistent with total density of states of graphite

Common variants in SOX-2 and congenital cataract genes contribute to age-related nuclear cataract

Nuclear cataract is the most common type of age-related cataract and a leading cause of blindness worldwide. Age-related nuclear cataract is heritable (h2 = 0.48), but little is known about specific genetic factors underlying this condition. Here we report findings from the largest to date multi-ethnic meta-analysis of genome-wide association studies (discovery cohort N = 14,151 and replication N = 5299) of the International Cataract Genetics Consortium. We confirmed the known genetic association of CRYAA (rs7278468, P = 2.8 × 10−16) with nuclear cataract and identified five new loci associated with this disease: SOX2-OT (rs9842371, P = 1.7 × 1

Effects of Exogenous Neuroglobin (Ngb) on retinal inflammatory chemokines and microglia in a rat model of transient hypoxia

10.1038/s41598-019-55315-3Scientific Reports911879

Biomechanical properties of bruch’s membrane-choroid complex and their influence on optic nerve head biomechanics

10.1167/iovs.17-22069Investigative Ophthalmology and Visual Science5972808-281

Transscleral cyclophotocoagulation and its histological effects on the conjunctiva

10.1038/s41598-019-55102-0Scientific Reports911870

Clinical features and survival outcomes of ocular melanoma in a multi-ethnic Asian cohort

10.1038/s41598-020-73534-xScientific Reports1011636