52 research outputs found
The Vehicle, 1966, Vol. 8
Vol. 8
Table of Contents
CommentaryBill Moser & Avis Eaglestonpage 3
The Vengeance of the DeadStephen W. Gibbspage 5
Ode To A MeadowKathleen McCormackpage 12
Row OnDavid Helmpage 13
Sonnet 63R.L. Hudsonpage 14
UntitledKathleen McCormackpage 14
The Pure GoldDavid Helmpage 15
CommunionDavid Helmpage 15
PreludeMichael Baldwinpage 15
The AlbatrossKaren Cooleypage 16
The Albatross (photo)DeWittpage 17
Ruff and the VaseDavid Helmpage 18
LaBelleKathleen McCormackpage 19
Not Quite SoR.L. Hudsonpage 20
Feeling (no number)David Reifpage 21
Song at DuskDavid Helmpage 21
Arcadia RuminationsR.L. Hudsonpage 22
The BarWayne Johnsonpage 25
HelloWilliam Framepage 26
The ProcessJerry DeWittpage 27
The KillingAdrian Beardpage 30
The Amusement Park GameStephen W. Gibbspage 38
DamnMel Tylerpage 40
PainWilliam Framepage 40
UntitledSusan Champlinpage 41
Portrait of A Scholar As A Young ManStephen W. Gibbspage 42
The TimesW.D.Mpage 46
ParadoxW.D.M.page 46
MankindDavid Helmpage 47https://thekeep.eiu.edu/vehicle/1014/thumbnail.jp
The Vehicle, 1966, Vol. 8
Vol. 8
Table of Contents
CommentaryBill Moser & Avis Eaglestonpage 3
The Vengeance of the DeadStephen W. Gibbspage 5
Ode To A MeadowKathleen McCormackpage 12
Row OnDavid Helmpage 13
Sonnet 63R.L. Hudsonpage 14
UntitledKathleen McCormackpage 14
The Pure GoldDavid Helmpage 15
CommunionDavid Helmpage 15
PreludeMichael Baldwinpage 15
The AlbatrossKaren Cooleypage 16
The Albatross (photo)DeWittpage 17
Ruff and the VaseDavid Helmpage 18
LaBelleKathleen McCormackpage 19
Not Quite SoR.L. Hudsonpage 20
Feeling (no number)David Reifpage 21
Song at DuskDavid Helmpage 21
Arcadia RuminationsR.L. Hudsonpage 22
The BarWayne Johnsonpage 25
HelloWilliam Framepage 26
The ProcessJerry DeWittpage 27
The KillingAdrian Beardpage 30
The Amusement Park GameStephen W. Gibbspage 38
DamnMel Tylerpage 40
PainWilliam Framepage 40
UntitledSusan Champlinpage 41
Portrait of A Scholar As A Young ManStephen W. Gibbspage 42
The TimesW.D.Mpage 46
ParadoxW.D.M.page 46
MankindDavid Helmpage 47https://thekeep.eiu.edu/vehicle/1014/thumbnail.jp
ZAP-70 Status May Not Predict Outcome after Non-Myeloablative Allogeneic Transplantation (NMT) in Patients with Chronic Lymphocytic Leukemia(CLL) Who Failed Conventional Chemotherapy.
Clinical Outcomes and Prognostic Factors in Patients With Richter's Syndrome Treated With Chemotherapy or Chemoimmunotherapy With or Without Stem-Cell Transplantation
Long-term follow-up of recipients of CD8-depleted donor lymphocyte infusions for the treatment of chronic myelogenous leukemia relapsing after allogeneic progenitor cell transplantation
CD25 expression on donor CD4+ or CD8+ T cells is associated with an increased risk for graft-versus-host disease after HLA-identical stem cell transplantation in humans
AbstractGraft-versus-host disease (GVHD) occurs in an unpredictable fashion after 30% to 50% of matched-related transplantations. The presence of increased frequencies of CD4+CD25+ regulatory T cells in donor grafts has been shown to ameliorate GVHD after allogeneic transplantation in murine models. To determine whether a similar relationship exists in humans, we quantitated the coexpression of CD25 on CD4+ and CD8+ T cells within 60 donor grafts infused into matched siblings and examined GVHD incidence in the respective recipients. Recipients in whom GVHD developed received donor grafts containing significantly higher frequencies of CD4+ T cells coexpressing CD25 than those who did not (median, 9.26% vs 2.22%; P = .004). Frequencies of donor graft CD8+ T cells coexpressing CD25 were also higher (0.65% vs 0.14%; P = .002). Furthermore, transplant recipients who received grafts containing fewer CD4+CD25+ and CD8+CD25+ T cells were less likely to acquire acute GVHD, even though these donor-recipient pairs were similar to others with respect to relevant clinical variables. These data suggest that the coexpression of CD4 and CD25 may be insufficient to identify regulatory T cells in humans and that increased frequencies and numbers of CD25+ T cells in donor grafts is associated with GVHD in transplant recipients. (Blood. 2004;103:1140-1146
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