INTERPENETRATING POLYMER NETWORK IN DRUG DELIVERY FORMULATIONS: REVISITED

Interpenetrating polymer network has gained a lot of interest in drug delivery system due to its ease of modification during its synthesis and development state, which evolved novel physicochemical and mechanical properties within the formulation. In this work, a detailed revision was done which includes its methods of preparations, factors that influence their properties, basic characterization parameters, and use in drug delivery systems along with patented formulations

Reversible Mode Switching in Y coupled Terahertz Lasers

Electrically independent terahertz (THz) quantum cascade lasers (QCLs) are optically coupled in a Y configuration. Dual frequency, electronically switchable emission is achieved in one QCL using an aperiodic grating, designed using computer-generated hologram techniques, incorporated directly into the QCL waveguide by focussed ion beam milling. Multi-moded emission around 2.9 THz is inhibited, lasing instead occurring at switchable grating-selected frequencies of 2.88 and 2.92 THz. This photonic control and switching behaviour is selectively and reversibly transferred to the second, unmodified QCL via evanescent mode coupling, without the transfer of the inherent grating losses

Y coupled terahertz quantum cascade lasers

Here we demonstrate a Y coupled terahertz (THz) quantum cascade laser (QCL) system. The two THz QCLs working around 2.85 THz are driven by independent electrical pulsers. Total peak THz output power of the Y system, with both arms being driven synchronously, is found to be more than the linear sum of the peak powers from the individual arms; 10.4 mW compared with 9.6 mW (4.7 mW + 4.9 mW). Furthermore, we demonstrate that the emission spectra of this coupled system are significantly different to that of either arm alone, or to the linear combination of their individual spectra.Comment: 9 pages, 3 figure

Sugar amino acids and related molecules: some recent developments

To meet the growing demands for the development of new molecular entities for discovering new drugs and materials, organic chemists have started working on many new concepts that can help to assimilate knowledge-based structural diversities more efficiently than ever before. Emulating the basic principles followed by Nature to build its vast repertoire of biomolecules, organic chemists are developing many novel multifunctional building blocks and using them to create 'nature-like' and yet unnatural organic molecules. Sugar amino acids constitute an important class of such polyfunctional scaffolds where the carboxyl, amino and hydroxyl termini provide an excellent opportunity to organic chemists to create structural diversities akin to Nature's molecular arsenal. In recent years, sugar amino acids have been used extensively in the area of peptidomimetic studies. Advances made in the area of combinatorial chemistry can provide the necessary technological support for rapid compilations of sugar amino acidbased libraries exploiting the diversities of their carbohydrate frameworks and well-developed solid-phase peptide synthesis methods. This perspective article chronicles some of the recent applications of various sugar amino acids, furan amino acids, pyrrole amino acids etc. and many other related building blocks in wide-ranging peptidomimetic studies

Tunneling images of a 2D electron system in a quantizing magnetic field

We have applied a scanning probe method, Subsurface Charge Accumulation (SCA) imaging, to resolve the local structure of the interior of a semiconductor two-dimensional electron system (2DES) in a tunneling geometry. Near magnetic fields corresponding to integer Landau level filling, submicron scale spatial structure in the out-of-phase component of the tunneling signal becomes visible. In the images presented here, the structure repeats itself when the filling factor is changed from nu=6 to nu=7. Therefore, we believe the images reflect small modulations in the 2DES density caused by the disorder in the sample.Comment: 2 pages, 2 color figures, submitted to LT23 proceeding

Two-way Mechanism to Enhance Confidentiality and Accuracy of Shared Information

As such internet and information technology have influenced the human life significantly thus the current technology cannot solely assure the security of shared information. Hence, to fulfil such requirements mass amount of research have been undertaken by various researchers among which one of the mechanisms is the use of dynamic key rather than static one. In this regard, we have proposed a method of key generation to provide the dynamic keys. The scheme not only can change the key but also provide the error control mechanism. At the end of this paper, a comparison with the existing techniques has also been made to prove the efficiency of the proposed scheme