8,200 research outputs found

    A new skew-elliptical distribution and its properties

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    This article generalizes a multivariate skew-elliptical distribution and describes its many interesting properties. The univariate version of the new distribution is compared with two other currently used distributions. The use of the new distribution is illustrated with a real data example suitable for regression modelling. The new model provides a better model fit than its two rivals as evaluated by some suitable Bayesian model selection criteria

    An optical study of interdiffusion in ZnSe/ZnCdSe

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    Copyright 1996 American Institute of Physics. This article may be downloaded for personal use only. Any other use requires prior permission of the author and the American Institute of Physics. This article appeared in Applied Physics Letters 69, 1579 (1996) and may be found at

    The activation energy for GaAs/AlGaAs interdiffusion

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    Copyright 1997 American Institute of Physics. This article may be downloaded for personal use only. Any other use requires prior permission of the author and the American Institute of Physics. This article appeared in Journal of Applied Physics 82, 4842 (1997) and may be found at

    Inferring gene regulatory networks from gene expression data by a dynamic Bayesian network-based model

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    Enabled by recent advances in bioinformatics, the inference of gene regulatory networks (GRNs) from gene expression data has garnered much interest from researchers. This is due to the need of researchers to understand the dynamic behavior and uncover the vast information lay hidden within the networks. In this regard, dynamic Bayesian network (DBN) is extensively used to infer GRNs due to its ability to handle time-series microarray data and modeling feedback loops. However, the efficiency of DBN in inferring GRNs is often hampered by missing values in expression data, and excessive computation time due to the large search space whereby DBN treats all genes as potential regulators for a target gene. In this paper, we proposed a DBN-based model with missing values imputation to improve inference efficiency, and potential regulators detection which aims to lessen computation time by limiting potential regulators based on expression changes. The performance of the proposed model is assessed by using time-series expression data of yeast cell cycle. The experimental results showed reduced computation time and improved efficiency in detecting gene-gene relationships

    Inferring gene regulatory networks from gene expression data by a dynamic Bayesian network-based model

    Get PDF
    Enabled by recent advances in bioinformatics, the inference of gene regulatory networks (GRNs) from gene expression data has garnered much interest from researchers. This is due to the need of researchers to understand the dynamic behavior and uncover the vast information lay hidden within the networks. In this regard, dynamic Bayesian network (DBN) is extensively used to infer GRNs due to its ability to handle time-series microarray data and modeling feedback loops. However, the efficiency of DBN in inferring GRNs is often hampered by missing values in expression data, and excessive computation time due to the large search space whereby DBN treats all genes as potential regulators for a target gene. In this paper, we proposed a DBN-based model with missing values imputation to improve inference efficiency, and potential regulators detection which aims to lessen computation time by limiting potential regulators based on expression changes. The performance of the proposed model is assessed by using time-series expression data of yeast cell cycle. The experimental results showed reduced computation time and improved efficiency in detecting gene-gene relationships

    Stability of a class of multi-agent tracking systems with unstable subsystems

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    In this work, we pre-deploy a large number of smart agents to monitor an area of interest. This area could be divided into many Voronoi cells by using the knowledge of Voronoi diagram and every Voronoi site agent is responsible for monitoring and tracking the target in its cell. Then, a cooperative relay tracking strategy is proposed such that during the tracking process, when a target enters a new Voronoi cell, this event triggers the switching of both tracking agents and communication topology. This is significantly different from the traditional switching topologies. In addition, during the tracking process, the topology and tracking agents switch, which may lead the tracking system to be stable or unstable. The system switches either among consecutive stable subsystems and consecutive unstable subsystems or between stable and unstable subsystems. The objective of this paper is to design a tracking strategy guaranteeing overall successful tracking despite the existence of unstable subsystems. We also address extended discussions on the case where the dynamics of agents are subject to disturbances and the disturbance attenuation level is achieved. Finally, the proposed tracking strategy is verified by a set of simulations

    Evaluation of stem rot in 339 Bornean tree species: implications of size, taxonomy, and soil-related variation for aboveground biomass estimates

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    Fungal decay of heart wood creates hollows and areas of reduced wood density within the stems of living trees known as stem rot. Although stem rot is acknowledged as a source of error in forest aboveground biomass (AGB) estimates, there are few data sets available to evaluate the controls over stem rot infection and severity in tropical forests. Using legacy and recent data from 3180 drilled, felled, and cored stems in mixed dipterocarp forests in Sarawak, Malaysian Borneo, we quantified the frequency and severity of stem rot in a total of 339 tree species, and related variation in stem rot with tree size, wood density, taxonomy, and species’ soil association, as well as edaphic conditions. Predicted stem rot frequency for a 50 cm tree was 53% of felled, 39% of drilled, and 28% of cored stems, demonstrating differences among methods in rot detection ability. The percent stem volume infected by rot, or stem rot severity, ranged widely among trees with stem rot infection (0.1–82.8 %) and averaged 9% across all trees felled. Tree taxonomy explained the greatest proportion of variance in both stem rot frequency and severity among the predictors evaluated in our models. Stem rot frequency, but not severity, increased sharply with tree diameter, ranging from 13% in trees 10–30 cm DBH to 54%in stems ≥ 50 cm DBH across all data sets. The frequency of stem rot increased significantly in soils with low pH and cation concentrations in topsoil, and stem rot was more common in tree species associated with dystrophic sandy soils than with nutrient-rich clays. When scaled to forest stands, the maximum percent of stem biomass lost to stem rot varied significantly with soil properties, and we estimate that stem rot reduces total forest AGB estimates by up to 7% relative to what would be predicted assuming all stems are composed strictly of intact wood. This study demonstrates not only that stem rot is likely to be a significant source of error in forest AGB estimation, but also that it strongly covaries with tree size, taxonomy, habitat association, and soil resources, underscoring the need to account for tree community composition and edaphic variation in estimating carbon storage in tropical forests
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