5 research outputs found

    Suppression of SOX7 by DNA methylation and its tumor suppressor function in acute myeloid leukemia

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    Key PointsSOX7 expression is silenced in common myeloid malignancies. SOX7 interacts directly with β-catenin and regulates the Wnt pathway in acute myeloid leukemia.</jats:p

    Homoharringtonine (omacetaxine mepesuccinate) as an adjunct for FLT3-ITD acute myeloid leukemia

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    An in vitro drug screening using primary AML samples identified homoharringtonine (omacetaxine mepesuccinate) as an effective adjunct for treatment of FLT3-ITD AML.</jats:p
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