The Influence of Dormitory Architecture On Resident Behavior

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/66943/2/10.1177_001391657300500402.pd

Conceptual design of an angular multiplexed 50 kJ KrF amplifier for ICF

The results of a conceptual design for an angular multiplexed 50 kJ KrF amplifier for ICF are presented. Optical designs, amplifier scaling with a KrF kinetics code and limitations imposed by pulsed power technology are described

STATUS OF THE MSNW TAPERED-WIGGLER FEL EXPERIMENT

Cet article décrit une étude expérimentale des principales caractéristiques d'un laser à électrons libres utilisant un "tapered-wiggler". L'effet de l'interaction laser sur la distribution d'énergie des électrons a été mesurée d'après l'amplification sur un passage simple des électrons et des photons à travers le "tapered-wiggler". Un pic de perte d'énergie des électrons a été observé. La décélération correspondante est de 9 % et de 2,5 % pour l'ensemble des électrons.This paper describes an experimental investigation of basic aspects of the tapered-wiggler free-electron laser. The effect of the PEL interaction on the electron energy distribution has been measured in a simple single pass amplifier configuration, with electrons and photons making a single pass through the tapered wiggler. A peak electron energy loss of about 9 percent and a net loss of 2.5 percent have been observed

Drug interaction potential of high-dose rifampicin in patients with pulmonary tuberculosis

Accumulating evidence supports the use of higher doses of rifampicin for tuberculosis (TB) treatment. Rifampicin is a potent inducer of metabolic enzymes and drug transporters, resulting in clinically relevant drug interactions. To assess the drug interaction potential of higher doses of rifampicin, we compared the effect of high-dose rifampicin (40 mg/kg daily, RIF40) and standard dose rifampicin (10 mg/kg daily, RIF10) on the activities of major cytochrome P450 (CYP) enzymes and P-glycoprotein (P-gp). In this open label, single-arm, two-period, fixed-order phenotyping cocktail study, adult participants with pulmonary TB received RIF10 (days 1-15), followed by RIF40 (days 16-30). A single dose of selective substrates (probe drugs) was administered orally on days 15 and 30: caffeine (CYP1A2), tolbutamide (CYP2C9), omeprazole (CYP2C19), dextromethorphan (CYP2D6), midazolam (CYP3A) and digoxin (P-gp). Intensive pharmacokinetic blood sampling was performed over 24 hours after probe drug intake. Twenty-five participants completed the study. Geometric mean ratios (90% CI) of the total exposure (area under the concentration versus time curve, RIF40 versus RIF10) for each of the probe drugs were: caffeine, 105% (96-115%); tolbutamide, 80% (74-86%); omeprazole, 55% (47-65%); dextromethorphan, 77% (68-86%); midazolam, 62% (49-78%), and 117% (105-130%) for digoxin. In summary, high-dose rifampicin resulted in no additional effect on CYP1A2, mild additional induction of CYP2C9, CYP2C19, CYP2D6 and CYP3A, and marginal inhibition of P-gp. Existing recommendations on managing drug interactions with rifampicin can remain unchanged for the majority of co-administered drugs when using high-dose rifampicin

Short-Term Soil Responses to Late-Seeded Cover Crops in a Semi-Arid Environment

Cover crops can expand ecosystem services, though sound management recommendations for their use within semiarid cropping systems is currently constrained by a lack of information. Th is study was conducted to determine agroecosystem responses to late-summer seeded cover crops under no-till management, with particular emphasis on soil attributes. Short-term effects of late-summer seeded cover crops on soil water, available N, nearsurface soil quality, and residue cover were investigated during three consecutive years on the Area IV Soil Conservation Districts Research Farm near Mandan, ND. Mean aboveground cover crop biomass was highly variable across years (1430, 96, and 937 kg ha–1 in 2008, 2009, and 2010, respectively), and was strongly affected by precipitation received within 14 d following cover crop seeding. During years with appreciable biomass production (2008 and 2010), cover crops significantly reduced available N in the 0.9-m depth the following spring (P = 0.0291 and 0.0464, respectively). Cover crop effects on soil water were subtle, and no differences in soil water were found between cover crop treatments and a no cover crop control before seeding cash crops the following spring. Late-summer seeded cover crops did not affect near-surface soil properties or soil coverage by residue. Soil responses to late-summer seeded cover crops did not diff er between cover crop mixtures and monocultures. Late-summer seeded cover crops may enhance ecosystem services provided by semiarid cropping systems through biomass production and N conservation, though achieving these benefits in a consistent manner appears dependent on timely precipitation following cover crop seeding

International Workbook: Political Participation (Japan)

Exercise sub-dataset for the Workbook ´Political Participation´. Topics: self-assessment of class; degree of party identification; perceived opportunity to influence the government; political interest; interest in the election campaign; interest in the election result; political interest of father during one´s childhood; participation in election events; personal donations; election participation at the last election; regional origin; perceived differences between the parties; media usage for political opinion making; party preference of parents during one´s childhood; judgement on one´s own economic situation; perceived class conflicts; class mobility; self-assessment on a left-right continuum; most important political topics; political attitude. Demography: age; sex; marital status; religious denomination; school education; characteristics of head of household; union membership; local residency; employment; occupational position; occupation; growing up in the city or the country; degree of relationship with head of household; social origins.Übungsteildatensatz zum Workbook "Political Participation". Themen: Selbsteinschätzung der Klassenzugehörigkeit; Grad der Parteiidentifikation; perzipierte Einflussmöglichkeit auf die Regierung; politisches Interesse; Interesse am Wahlkampf; Interesse am Wahlausgang; politisches Interesse des Vaters während der eigenen Kindheit; Teilnahme an Wahlveranstaltungen; eigene Spenden; Wahlbeteiligung bei der letzten Wahl; regionale Herkunft; wahrgenommene Unterschiede zwischen den Parteien; Mediennutzung zur politischen Meinungsbildung; Parteipräferenz der Eltern während der eigenen Kindheit; Beurteilung der eigenen wirtschaftlichen Situation; perzipierte Klassenkonflikte; Klassenmobilität; Selbsteinschätzung auf einem Links-Rechts-Kontinuum; wichtigste politische Themen; politische Einstellung. Demographie: Alter; Geschlecht; Familienstand; Konfession; Schulbildung; Charakteristika des Haushaltsvorstands; Gewerkschaftsmitgliedschaft; Ortsansässigkeit; Berufstätigkeit; berufliche Position; Beruf; Aufwachsen in der Stadt oder auf dem Land; Verwandtschaftsverhältnis zum Haushaltsvorstand; soziale Herkunft