Disformal invariance of continuous media with linear equation of state

We show that the effective theory describing single component continuous media with a linear and constant equation of state of the form $p=w\rho$ is invariant under a 1-parameter family of continuous disformal transformations. In the special case of $w=1/3$ (ultrarelativistic gas), such a family reduces to conformal transformations. As examples, perfect fluids, homogeneous and isotropic solids are discussed.Comment: latex, 7 page

Living with ghosts in Horava-Lifshitz gravity

We consider the branch of the projectable Horava-Lifshitz model which exhibits ghost instabilities in the low energy limit. It turns out that, due to the Lorentz violating structure of the model and to the presence of a finite strong coupling scale, the vacuum decay rate into photons is tiny in a wide range of phenomenologically acceptable parameters. The strong coupling scale, understood as a cutoff on ghosts' spatial momenta, can be raised up to $\Lambda \sim 10$ TeV. At lower momenta, the projectable Horava-Lifshitz gravity is equivalent to General Relativity supplemented by a fluid with a small positive sound speed squared ($10^{-42}\lesssim$) $c^2_s \lesssim 10^{-20}$, that could be a promising candidate for the Dark Matter. Despite these advantages, the unavoidable presence of the strong coupling obscures the implementation of the original Horava's proposal on quantum gravity. Apart from the Horava-Lifshitz model, conclusions of the present work hold also for the mimetic matter scenario, where the analogue of the projectability condition is achieved by a non-invertible conformal transformation of the metric.Comment: 33 pages, 1 figure. The proof of an equivalence between the IR limit of the projectable Horava-Lifshitz gravity and the mimetic matter scenario is given in Appendix A. Version accepted for publication in JHE

Increased circulating ANG II and TNF-α represents important risk factors in obese Saudi adults with hypertension irrespective of diabetic status and BMI

Central adiposity is a significant determinant of obesity-related hypertension risk, which may arise due to the pathogenic inflammatory nature of the abdominal fat depot. However, the influence of pro-inflammatory adipokines on blood pressure in the obese hypertensive phenotype has not been well established in Saudi subjects. As such, our study investigated whether inflammatory factors may represent useful biomarkers to delineate hypertension risk in a Saudi cohort with and without hypertension and/or diabetes mellitus type 2 (DMT2). Subjects were subdivided into four groups: healthy lean controls (age: 47.9±5.1 yr; BMI: 22.9±2.1 Kg/m2), non-hypertensive obese (age: 46.1±5.0 yr; BMI: 33.7±4.2 Kg/m2), hypertensive obese (age: 48.6±6.1 yr; BMI: 36.5±7.7 Kg/m2) and hypertensive obese with DMT2 (age: 50.8±6.0 yr; BMI: 35.3±6.7 Kg/m2). Anthropometric data were collected from all subjects and fasting blood samples were utilized for biochemical analysis. Serum angiotensin II (ANG II) levels were elevated in hypertensive obese (p<0.05) and hypertensive obese with DMT2 (p<0.001) compared with normotensive controls. Systolic blood pressure was positively associated with BMI (p<0.001), glucose (p<0.001), insulin (p<0.05), HOMA-IR (p<0.001), leptin (p<0.01), TNF-α (p<0.001) and ANG II (p<0.05). Associations between ANG II and TNF-α with systolic blood pressure remained significant after controlling for BMI. Additionally CRP (p<0.05), leptin (p<0.001) and leptin/adiponectin ratio (p<0.001) were also significantly associated with the hypertension phenotype. In conclusion our data suggests that circulating pro-inflammatory adipokines, particularly ANG II and, TNF-α, represent important factors associated with a hypertension phenotype and may directly contribute to predicting and exacerbating hypertension risk

Effectiveness of acupuncture, special dressings and simple, low-adherence dressings for healing venous leg ulcers in primary healthcare: study protocol for a cluster-randomized open-labeled trial

<p>Abstract</p> <p>Background</p> <p>Venous leg ulcers constitute a chronic recurring complaint that affects 1.0–1.3% of the adult population at some time in life, and which corresponds to approximately 75% of all chronic ulcers of the leg. Multilayer compression bandaging is, at present, the only treatment that has been proved to be effective in treating this type of ulcer. There is no consensus, however, about the dressings that may be applied, beneath the compression, to promote the healing of this type of ulcer, as there does not seem to be any added benefit from using special dressings rather than simple, low-adherence ones. As well as analgesia, acupuncture provokes peripheral vasodilation, in skin and muscles – which has been demonstrated both experimentally and in clinical practice – probably due to the axon reflex, among other mechanisms. The aim of the present study is to measure the effectiveness and cost of compression treatment for venous leg ulcers combined with special dressings, in comparison with low-adherence ones and acupuncture.</p> <p>Methods/design</p> <p>Cluster-randomized open-labeled trial, at 15 primary healthcare clinics in the Sevilla-Sur Healthcare District, with a control group treated with compression bandaging and low-adherence dressings; the experiment will consist, on the one hand, of the compression treatment applied in combination with special dressings (Treatment 1), and on the other, the compression treatment applied in association with low-adherence dressings, together with acupuncture (Treatment 2).</p> <p>Discussion</p> <p>The results will be measured and recorded in terms of the median time elapsed until complete healing of the ulcer, and the rate of complete healing at 3 months after beginning the treatment. An economic analysis will also be made.</p> <p>This study, carried out in the context of real clinical practice, will provide information for decision-taking concerning the effectiveness of special dressings. Moreover, for the first time a high-quality study will evaluate the effectiveness of acupuncture in the process of healing venous leg ulcers.</p> <p>Trial registration</p> <p>Current Controlled Trials ISRCTN26438275.</p

NOTAS E RESENHAS

COBERTURA VEGETAL, POLUIÇÃO AÉREA E DESLIZAMENTOS NA SERRA DO MAR – Helmut TROPPMAIR e Maria Eugênia M. C. FERREIRA. A ECONOMIA POLÍTICA DO COMPLEXO AGROINDUSTRIAL BRASILEIRO (Notas Básicas para Elaboração de um Programa de Pesquisa) - Geraldo MULLER SISTEMAS DA SUPERFÍCIE TERRESTRE - Antonio CHRISTOFOLETTI GEOMORFOLOGIA DINÂMICA, AMBIENTAL E PALEOECOLOGIA - Antonio CHRISTOFOLETTI ANÁLISE, MONITORIAMENTO E PREVISÃO EM HIDROLOGIA - Antonio CHRISTOFOLETTI ENSINO DA GEOGRAFIA - Antonio CHRISTOFOLETTI ATLAS NACIONAL DO BRASIL - REGIÃO NORDESTE - Miguel Cezar SANCHEZ INTRODUÇÃO À BIODETERIORAZÃO - Myrian Cecilia ROLIM PROCHNOW REFLORESTAMENTO E IMPACTOS AMBIENTAIS - Maria Juraci ZANI DOS SANTOS FORMA URBANA E A NOVA TECNOLOGIA - Pompeu FIGUEIREDO DE CARVALHO O CAPITAL FINANCEIRO E O MERCADO IMOBILIÁRIO DE ESCRITÓRIOS - Pompeu FIGUEIREDO DE CARVALHO O PODER DA BUROCRACIA – R. BATLEY DIALÉTICA DO CONCRETO - Aldomar Arnaldo RUCHERT INTELIGÊNCIA ARTIFICIAL - João Francisco DE ABREU SISTEMAS DE INFORMAÇÃO PARA PLANEJAMENTO REGIONAL - João Francisco DE ABREU ANÁLISE DOS FLUXOS DE MIGRAÇÃO - João Francisco DE ABREU MODELOS PROJETIVOS DA POPULAÇÃO REGIONAL - João Francisco DE ABREU REPRESENTAÇÃO GRÀFICA DAS INFORMAÇÕES QUANTITATIVAS - João Francisco DE ABREU A CULTURA DO ARROZ - Ana Tereza CACERES CORTEZ MORAES O OCEANO MIOCÊNICO - Reinaldo José BERTINI PROGRESS IN PHYSICAL AND IN HUMAN GEOGRAPHY 1985-1986 - Antonio CHRISTOFOLETTI CONCEITOS E TÉCNICAS EM GEOGRAFIA - Antonio CHRISTOFOLETTI GEOGRAFIA ECONÔMICA DA HÚNGRIA - Antonio CHRISTOFOLETTI PRAGAS E VENENOS: AGROTÓXICOS NO BRASIL E NO TERCEIRO MUNDO - Lígia Celoria POLTRONIÉRI O ESCÂNDALO DAS SEMENTES: O DOMÍNIO NA PRODUÇÃO DE ALIMENTOS - Lígia Celoria POLTRONIÉR