Bioactive Content of Sea Buckthorn (Hippophae rhamnoides L.) Berries from Turkey

In Northeast part in Turkey, wild grown fruits are abundant and they are widely collected and consumed by rural peoples. In this study, the fruits of seven sea buckthorn genotypes from Northeast in Turkey were sampled and analyzed for their total phenolic content, vitamin C, total anthocyanins and antioxidant capacity. Total phenolic, vitamin C and total anthocyanin content varied from 213 to 262 mg GAE/100g FW; 28-85 mg/100 g and 3-21 mg/L among genotypes. Antioxidant capacity analyses (in DPPH and β-carotene method) showed that all samples had a high antioxidant (average 94.23% in β-Carotene and 31.23% in DPPH) capacity

Dieulafoy lesions: One patient, two different localizations

Dieulafoy lesions (DLs) are dilated submucosal arterial structures visualized on endoscopy as bleeding foci on the superficial mucosa without erosion or ulceration. DLs account for 1-5.8% of acute non-variceal upper gastrointestinal bleeding cases. A 72-year-old male patient with known Alzheimer's disease and coronary artery disease, being followed up at a nursing home, presented to our emergency department with foul-smelling, loose, and tarry stool. Esophagogastroduodenoscopy revealed a 3 mm DL immediately adjacent to the Z line in the distal esophagus, demonstrating a fresh blood clot without the appearance of a surrounding ulcer. Two endoscopic hemo-clips were applied to this lesion. The patient was monitored at the intensive care unit for the following 2 days and later transferred to internal medicine inpatient unit. He developed hematochezia on the 8th day of hospitalization. Emergent rectosigmoidoscopy was per-formed showing two separate 3 and 4 mm sized DLs, located immediately proximal to the dentate line. These lesions were successfully treated using two endoscopic band ligations. DLs can occur synchronously, albeit very rarely, and a careful search for multiple lesions is necessary to avoid further bleeding

The Effect of Herbicides on Russian Wheat Aphid, Diuraphis noxia (Kurdjumov) (Hemiptera: Aphididae)

WOS: 000376051000005Russian wheat aphids (Diuraphis noxia) are one of the most important pests on wheat in the world. This study was conducted to determine the effect of selected herbicides on the Russian wheat aphids. D. noxia were reared on wheat and all herbicide experiments conducted under controlled laboratory conditions. Assessments were made before the application of herbicides, and at 3, 7, 14 and 21 days after application (DAA). The lowest densities of D. noxia were seen on 2,4-D ester-treated plants. The smallest leaf chlorosis caused by D. noxia was found on tribenuron-methyl-treated plants at 3 DAA, and tribenuron-methyl-treated plants had the lowest leafrolling damage caused by D. noxia. Although all untreated plants were easily broken at the soil surface at 21 DAA, it was observed that all herbicide-treated plants were bent downward slightly but not broken. The active ingredients of fenoxaprop-p-ethyl+fenohlorazole-ethyl, tribenuron-methyl and 2,4-D ester had a negative impact on D. noxia, and suppressed aphid populations from 3 DAA. Statistical analyses showed that effects of all herbicides used in the experiment were significant.TUBITAK (The Scientific and Technological Research Council of Turkey)Turkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [110 O 636]We would like to thank TUBITAK (The Scientific and Technological Research Council of Turkey) (Project Number: 110 O 636) for financial support and Agrobest Group Firm for providing herbicides

The first report of oxcarbazepine-induced vanishing bile duct syndrome

WOS: 000337333300020PubMed ID: 2494961

Fluoride release from esthetic restorative materials with and without adhesive

WOS: 000238086300010PubMed ID: 16475377Objective: The purpose of this in vitro study was to compare the effect of surface coating containing fluoride on patterns and amounts of fluoride release from 5 esthetic restorative materials. Method and materials: Twelve cylinders of each material were prepared in a plexiglass mold. The experimental groups (n = 6) were coated with 1 layer of fluoridated adhesive resin, Prompt L-Pop, while the control groups (n = 6) remained uncoated. Fluoride release into deionized water was measured on days 1, 2, 3, 7, 14, 21, and 28 using an ion analyzer. Results were evaluated statistically using repeated measure analysis of variance and Duncan test. Results: In the uncoated materials, the highest fluoride-releasing material was a resin composite Ariston pHc (140.468 +/- 9.80) followed by Photac-fil (101.200 +/- 5.56), Ketac-fil (91.098 +/- 4.69), Hytac Aplitip (5.122 +/- 1.00), and Ecusit (0.310 +/- 0.18). Material-coating interaction was found to be significant, but the effect of surface coating was different for each material. Among the coated materials, conventional glass-ionomer cement Ketac-fil released the highest amount of fluoride (93.326 +/- 10.86), followed by Photac-fil (83.666 +/- 4.72), Ariston pHc (53.862 +/- 7.90), Hytac Aplitip (14.634 +/- 2.35), and Ecusit (1.355 +/- 0.29). Conclusion: Application of fluoridated adhesive affected fluoride release from each material in varying magnitudes

Bioactive Content of Sea Buckthorn (Hippophae rhamnoides L.) Berries from Turkey

In Northeast part in Turkey, wild grown fruits are abundant and they are widely collected and consumed by rural peoples. In this study, the fruits of seven sea buckthorn genotypes from Northeast in Turkey were sampled and analyzed for their total phenolic content, vitamin C, total anthocyanins and antioxidant capacity. Total phenolic, vitamin C and total anthocyanin content varied from 213 to 262 mg GAE/100g FW; 28-85 mg/100 g and 3-21 mg/L among genotypes. Antioxidant capacity analyses (in DPPH and β-carotene method) showed that all samples had a high antioxidant (average 94.23% in β-Carotene and 31.23% in DPPH) capacity

Role of Allogeneic Stem Cell Transplant in the Treatment of Primary Myelofibrosis

###EgeUn###Objectives: The only known curative therapy for primary myelofibrosis is allogeneic hematopoietic stem cell transplant. Materials and Methods: We retrospectively evaluated 11 transplant procedures involving 10 patients (5 men and 5 women) diagnosed with primary myelofibrosis between 2005 and 2014. Results: The median age at the time of transplant was 60.5 years (range, 22-62 years). Stem cell sources were unrelated (n = 1) and related (n = 11) peripheral blood stem cells. Conditioning regimen was myeloablative for 8 and reduced intensity for 3 transplants. The median number of infused CD34+ cells was 6.8 x 10(6) cells/kg (range, 3.2-10.4 x 10(6) cells/kg). Neutrophil and platelet engraftment occurred at median of 22 days (range, 12-31 days) and 19.5 days (range, 13-56 days). Acute and chronic graft-versus-host disease was seen in 4 of 11 allografts. Relapse and nonrelapse mortality rates were 20%. Six patients (60%) were still alive without disease after median follow-up of 68.5 months (range, 17-120 months). Median progression-free survival and overall survival were 61 months (range, 2-120 months) and 65 months (range, 2-120 months). Conclusions: Our results suggest that allogeneic hematopoietic stem cell transplant may provide a curative treatment for primary myelofibrosis patients. A myeloablative regimen seems to be effective and safe, especially for younger primary myelofibrosis patients

Determination of Phenolic Compounds, Antioxidant Capacity and Organic Acids Contents of Prunus domestica L., Prunus cerasifera Ehrh. and Prunus spinosa L. Fruits by HPLC

WOS: 000416256600013The important role of fruits in human health and nutrition has been better understood with the recent studies on biochemical contents of fruits having antioxidant properties. Being one of the similar studies, in this study, total antioxidant capacity (TAC), phenolic compound, organic acid, and vitamin C contents of three plum species (Prunus domestica L., Prunus cerasifera Ehrh., and Prunus spinosa L.) grown in Van locality (Turkey) were identified, and the correlation between the measured values was investigated. Phenolic compound, organic acid, and vitamin C contents were determined by high-performance liquid chromatography (HPLC) method. Analysis of phenolic compound indicated that chlorogenic acid was the predominant phenolic compound, and the highest value was measured in P. spinosa L. as 12.985 mg kg(-1). Malic acid was the predominant organic acids and the highest value was measured in P. spinosa L. as 1.245 g 100 g(-1). The highest TAC and vitamin C contents were also measured in P. spinosa L. as 1.021 mmol TE kg(-1) and 25.492 mg 100 g(-1), respectively. P. spinosa L. was found to be superior to the other two species with respect to antioxidant capacity and other biochemical contents. A significant (P <= 0.01) and positive correlation was reported between antioxidant capacity and vitamin C content