18F-fluoro-2-deoxy-D-glucose positron emission tomographic imaging: recent developments in head and neck cancer.

Positron emission tomography using 18F-fluoro-2-deoxy-D-glucose (18FDG-PET) is well established in clinical routine as a metabolism-based whole-body imaging tool for cancer diagnosis and follow-up. Several reports have appeared indicating the potential and limitations of this technique in head and neck cancer (HNC). This review limits its scope to the recent advances using 18FDG-PET in the clinical management of HNC.Journal ArticleReviewSCOPUS: re.jinfo:eu-repo/semantics/publishe

Lung, Gastric, and Soft Tissue Uptake of Tc-99m MDP and Ga-67 Citrate Associated with Hypercalcemia

Metastatic calcifications are associated with chronic renal failure, hyperparathyroidism, metastatic neoplasms, hypervitaminosis D, and hypercalcemia of other origins. Bone scanning agents accumulate within these extraskeletal metastatic calcifications. The authors describe two patients with hypercalcemia associated with Tc-99m MDP uptake in the lungs, stomach, and soft tissues. Ga-67 scintigraphy was also performed and showed increased uptake in the same locations as those of Tc-99m MDP, suggesting the existence of an inflammatory process. Despite adequate treatment, only partial resolution of extraskeletal uptake was observed.SCOPUS: ar.jSCOPUS: ar.jinfo:eu-repo/semantics/publishe

Whole-body 18F-fluorodeoxyglucose positron emission tomography/computed tomography (FGD PET/CT) and extrapulmonary tuberculosis in HIV patients

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Use of FDG-PET/CT imaging in the diagnosis of low-grade HIV associated Lymphoproliferative disorders

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Rôle de la TEP FDG chez le patient VIH+ souffrant de fièvre d’origine indeterminée: Comparaison avec des patients virémiques asymptomatique

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Role and interpretation of FDG-PET/CT in HIV patients with fever of unknown origin: a prospective study

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Role and interpretation of FDG-PET/CT in HIV patients with fever of unknown origin: a prospective study

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FDG-PET/CT: a non-invasive tool in diagnosis and monitoring of therapeutic response in HIV patients with extra-pulmonary tuberculosis

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Clinical value of FDG-PET/CT for the diagnosis of human immunodeficiency virus-associated fever of unknown origin: A retrospective study

Aim: The aim of this study was to evaluate retrospectively the usefulness of [18F]fluorodeoxyglucose (FDG)-PET/computed tomography (CT) in patients affected by human immunodeficiency virus and suffering from fever of unknown origin (HIV-associated FUO). Material and methods: Ten patients (six males, four females, age 24-48 years) suffering from HIV-associated FUO were studied by FDG-PET/CT. Final diagnosis was established either by microbiological or histopathological analysis or by a more than 6-month follow-up. FDG-PET/CT was regarded as 'helpful for diagnosis' when the abnormal uptake pointed to the organ or location where the cause of fever was thereafter identified. Results: Nine out of 10 FDG-PET/CT were abnormal and the cause of fever was further demonstrated by other diagnostic procedures. An infectious process (tuberculosis) was diagnosed in six patients and a neoplasm in three (two lymphomas, one Kaposi's sarcoma). FDG-PET/CT directly suggested sites for biopsy in six patients (tuberculous lymphadenitis and neoplasm). The only patient with normal FDG-PET/CT suffered from drug-induced fever. Conclusion: FDG-PET/CT is a valuable tool in patients with HIV-associated FUO. FDG-PET/CT was categorized as 'helpful for diagnosis' in nine out of the 10 patients we studied. Adding the CT anatomical landmarks to the PET findings allowed an accurate and easy localization of the sites to be punctured in the six patients in whom histopathological diagnosis was needed. © 2009 Wolters Kluwer HealthSCOPUS: ar.jinfo:eu-repo/semantics/publishe

Prospective serial FDG PET/CT during treatment of extrapulmonary tuberculosis in HIV-infected patients: An exploratory study

Purpose The aim of this study was to prospectively describe evolution of 18F-FDG uptake of extrapulmonary tuberculosis (TB) throughout the course of TB treatment in HIV patients to evaluate 18F-FDG PET/CT as a monitoring tool of treatment response. Methods We performed baseline FDG PET/CT, PET-2 after 2 months, and PET-3 at the end of TB treatment in 18 HIV/TB patients. We correlated evolution of FDG uptake with clinical outcome of patients. Results After 2 months of treatment, 78% of the patients had a significant metabolic response. Lymph node (LN) metabolic response was heterogeneous, with 57% of LN sites showing decreased SUVmax and 41% showing unchanged FDG uptake. Organs other than LNs showed more homogeneous response. The FDG PET/CT performed at the end of TB treatment showed a complete response of all infected organs and a drastic response in terms of active LNs in 95% of the patients (SUVmax mean decrease = 85%, median = 100%). A complete metabolic response after TB treatment was seen in only 47% of patients. Conclusions In difficult-to-treat entities such as extrapulmonary TB in HIV patients, FDG PET/CT is a potential tool in monitoring TB treatment response and should be explored in larger studies.SCOPUS: ar.jinfo:eu-repo/semantics/publishe